Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey

Hüseyin Servi; Ali Şen; Esra Yıldırım Servi; Ahmet Doğan

Makale detayları

Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey

Yazarlar:

Hüseyin Servi | Ali Şen | Esra Yıldırım Servi | Ahmet Doğan

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.25 Issue 2, pp.142-152

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347807

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 The chemical composition of essential oils of aerial parts of Daucus carota DEO and Foeniculum vulgare FEO was specified by GCMS. Antidiabetic, anti-inflammatory, antioxidant, and antibacterial activities of oils were tested by -glucosidase inhibitory, 5-lipoxygenase inhibitory, DPPHABTS radical scavenging, and broth microdilution methods, respectively. Thirty components were identified in DEO 87.7. Carotol 27.7, elemicin 18.1, and limonene 16.0 were determined as the main compounds in DEO. Seventeen constituents were identified in FEO 100.0. Estragole 34.0, limonene 27.1, and -pinene 19.5 were found as major components in FEO. Both oils displayed weak antibacterial activity against Gram-negative bacteria. However, the oils were not effective on Gram- positive bacteria. DEO with IC50 values of 1359 and 1579 μgmL and FEO with IC50 values of 3106 and 1654 μgmL showed weak antioxidant activities against DPPH and ABTS radicals, respectively. DEO and FEO exhibited good anti- lipoxygenase activities with IC50 values of 87.24 and 58.35 μgmL, respectively. DEO presented significantly - glucosidase inhibitory activity with an IC50 value of 44.78 µgmL while FEO displayed poor activity with an IC50 value of 1967 µgmL. This study is the first report on the 5-lipoxygenase and -glucosidase inhibitory activities of aerial parts of DEO as well as on the -glucosidase inhibitory activity of aerial parts of FEO. These results indicated that DEO, which has a good antidiabetic and anti-inflammatory activity, is rich in oxygenated sesquiterpene and monoterpene. Also, it showed that FEO, which has a significant anti-inflammatory activity, is rich in monoterpene and phenylpropanoid.

 The chemical composition of essential oils of aerial parts of Daucus carota DEO and Foeniculum vulgare FEO was specified by GCMS. Antidiabetic, anti-inflammatory, antioxidant, and antibacterial activities of oils were tested by -glucosidase inhibitory, 5-lipoxygenase inhibitory, DPPHABTS radical scavenging, and broth microdilution methods, respectively. Thirty components were identified in DEO 87.7. Carotol 27.7, elemicin 18.1, and limonene 16.0 were determined as the main compounds in DEO. Seventeen constituents were identified in FEO 100.0. Estragole 34.0, limonene 27.1, and -pinene 19.5 were found as major components in FEO. Both oils displayed weak antibacterial activity against Gram-negative bacteria. However, the oils were not effective on Gram- positive bacteria. DEO with IC50 values of 1359 and 1579 μgmL and FEO with IC50 values of 3106 and 1654 μgmL showed weak antioxidant activities against DPPH and ABTS radicals, respectively. DEO and FEO exhibited good anti- lipoxygenase activities with IC50 values of 87.24 and 58.35 μgmL, respectively. DEO presented significantly - glucosidase inhibitory activity with an IC50 value of 44.78 µgmL while FEO displayed poor activity with an IC50 value of 1967 µgmL. This study is the first report on the 5-lipoxygenase and -glucosidase inhibitory activities of aerial parts of DEO as well as on the -glucosidase inhibitory activity of aerial parts of FEO. These results indicated that DEO, which has a good antidiabetic and anti-inflammatory activity, is rich in oxygenated sesquiterpene and monoterpene. Also, it showed that FEO, which has a significant anti-inflammatory activity, is rich in monoterpene and phenylpropanoid.

 The chemical composition of essential oils of aerial parts of Daucus carota DEO and Foeniculum vulgare FEO was specified by GCMS. Antidiabetic, anti-inflammatory, antioxidant, and antibacterial activities of oils were tested by -glucosidase inhibitory, 5-lipoxygenase inhibitory, DPPHABTS radical scavenging, and broth microdilution methods, respectively. Thirty components were identified in DEO 87.7. Carotol 27.7, elemicin 18.1, and limonene 16.0 were determined as the main compounds in DEO. Seventeen constituents were identified in FEO 100.0. Estragole 34.0, limonene 27.1, and -pinene 19.5 were found as major components in FEO. Both oils displayed weak antibacterial activity against Gram-negative bacteria. However, the oils were not effective on Gram- positive bacteria. DEO with IC50 values of 1359 and 1579 μgmL and FEO with IC50 values of 3106 and 1654 μgmL showed weak antioxidant activities against DPPH and ABTS radicals, respectively. DEO and FEO exhibited good anti- lipoxygenase activities with IC50 values of 87.24 and 58.35 μgmL, respectively. DEO presented significantly - glucosidase inhibitory activity with an IC50 value of 44.78 µgmL while FEO displayed poor activity with an IC50 value of 1967 µgmL. This study is the first report on the 5-lipoxygenase and -glucosidase inhibitory activities of aerial parts of DEO as well as on the -glucosidase inhibitory activity of aerial parts of FEO. These results indicated that DEO, which has a good antidiabetic and anti-inflammatory activity, is rich in oxygenated sesquiterpene and monoterpene. Also, it showed that FEO, which has a significant anti-inflammatory activity, is rich in monoterpene and phenylpropanoid.

 The chemical composition of essential oils of aerial parts of Daucus carota DEO and Foeniculum vulgare FEO was specified by GCMS. Antidiabetic, anti-inflammatory, antioxidant, and antibacterial activities of oils were tested by -glucosidase inhibitory, 5-lipoxygenase inhibitory, DPPHABTS radical scavenging, and broth microdilution methods, respectively. Thirty components were identified in DEO 87.7. Carotol 27.7, elemicin 18.1, and limonene 16.0 were determined as the main compounds in DEO. Seventeen constituents were identified in FEO 100.0. Estragole 34.0, limonene 27.1, and -pinene 19.5 were found as major components in FEO. Both oils displayed weak antibacterial activity against Gram-negative bacteria. However, the oils were not effective on Gram- positive bacteria. DEO with IC50 values of 1359 and 1579 μgmL and FEO with IC50 values of 3106 and 1654 μgmL showed weak antioxidant activities against DPPH and ABTS radicals, respectively. DEO and FEO exhibited good anti- lipoxygenase activities with IC50 values of 87.24 and 58.35 μgmL, respectively. DEO presented significantly - glucosidase inhibitory activity with an IC50 value of 44.78 µgmL while FEO displayed poor activity with an IC50 value of 1967 µgmL. This study is the first report on the 5-lipoxygenase and -glucosidase inhibitory activities of aerial parts of DEO as well as on the -glucosidase inhibitory activity of aerial parts of FEO. These results indicated that DEO, which has a good antidiabetic and anti-inflammatory activity, is rich in oxygenated sesquiterpene and monoterpene. Also, it showed that FEO, which has a significant anti-inflammatory activity, is rich in monoterpene and phenylpropanoid.

Makale detayları

Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey

Yazarlar:

Hüseyin Servi | Ali Şen | Esra Yıldırım Servi | Ahmet Doğan

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.25 Issue 2, pp.142-152

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347807

pISSN:

2630-6344

Daucus carota

Foeniculum vulgare

essential oils

biological activity

Sayı

Makale detayları

Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey

Yazarlar: Hüseyin Servi | Ali Şen | Esra Yıldırım Servi | Ahmet Doğan

Yayıncı: Marmara University

Ana Başlıklar: Pharmacognosy

Dergi: Journal of Research in Pharmacy Vol.25 Issue 2, pp.142-152

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001347807

pISSN: 2630-6344

Daucus carota

Foeniculum vulgare

essential oils

biological activity

Sayı

Yazarlar:

Hüseyin Servi | Ali Şen | Esra Yıldırım Servi | Ahmet Doğan

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.25 Issue 2, pp.142-152

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347807

pISSN:

2630-6344