The frequency and associated factors of erosive osteoarthritis in patients with rheumatoid arthritis

Mete Pekdiker; İnan Korkmaz; Sertaç Ketenci

Makale detayları

The frequency and associated factors of erosive osteoarthritis in patients with rheumatoid arthritis

Yazarlar:

Mete Pekdiker | İnan Korkmaz | Sertaç Ketenci

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Rheumatology and Arthritis

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 4, pp.733-737

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001338251

pISSN:

1309-4483

Anahtar kelimeler:

Özet:

 Erosive osteoarthritis EOA is a deformative joint disease affecting small joints of hands that causes pain and disability, as does rheumatoid arthritis RA. So, EOA may interfere with the assessment of RA disease activity. In this study, we aimed to determine the frequency and associated factors of EOA in patients with RA and pay attention to the overlap syndrome between RA and EOA. The electronic medical files of adult RA patients were reviewed retrospectively. Patients with another rheumatic diseases were excluded. Hand X-rays were read by two rheumatologists and one radiologist. Patients with RA were divided into two groups according to the presence of EOA. We totally analyzed 619 patients with a mean age of 54.2 years, and 82.8 of them were female. The 95.4 of patients had RA-type erosive changes according to the Modified Sharp Score. We found the frequency of EOA to be 6.3 in patients with RA. Erosive osteoarthritis was significantly higher in patients who had 50 years of age p 0.006, disease duration 10 years p 0.003, and anti-CCP negativity p 0.02 than in those without. In multivariable regression analysis, only age was the independent predictive factor for EOA p0.001 in RA patients. We published the frequency and associated risk factors of EOA in RA for the first time in literature. Rheumatologists should take EOA into account when making treatment decisions in middle agedelderly RA population. Further prospective studies are needed to explain the linkage between RA and EOA.

 Erosive osteoarthritis EOA is a deformative joint disease affecting small joints of hands that causes pain and disability, as does rheumatoid arthritis RA. So, EOA may interfere with the assessment of RA disease activity. In this study, we aimed to determine the frequency and associated factors of EOA in patients with RA and pay attention to the overlap syndrome between RA and EOA. The electronic medical files of adult RA patients were reviewed retrospectively. Patients with another rheumatic diseases were excluded. Hand X-rays were read by two rheumatologists and one radiologist. Patients with RA were divided into two groups according to the presence of EOA. We totally analyzed 619 patients with a mean age of 54.2 years, and 82.8 of them were female. The 95.4 of patients had RA-type erosive changes according to the Modified Sharp Score. We found the frequency of EOA to be 6.3 in patients with RA. Erosive osteoarthritis was significantly higher in patients who had 50 years of age p 0.006, disease duration 10 years p 0.003, and anti-CCP negativity p 0.02 than in those without. In multivariable regression analysis, only age was the independent predictive factor for EOA p0.001 in RA patients. We published the frequency and associated risk factors of EOA in RA for the first time in literature. Rheumatologists should take EOA into account when making treatment decisions in middle agedelderly RA population. Further prospective studies are needed to explain the linkage between RA and EOA.

 Erosive osteoarthritis EOA is a deformative joint disease affecting small joints of hands that causes pain and disability, as does rheumatoid arthritis RA. So, EOA may interfere with the assessment of RA disease activity. In this study, we aimed to determine the frequency and associated factors of EOA in patients with RA and pay attention to the overlap syndrome between RA and EOA. The electronic medical files of adult RA patients were reviewed retrospectively. Patients with another rheumatic diseases were excluded. Hand X-rays were read by two rheumatologists and one radiologist. Patients with RA were divided into two groups according to the presence of EOA. We totally analyzed 619 patients with a mean age of 54.2 years, and 82.8 of them were female. The 95.4 of patients had RA-type erosive changes according to the Modified Sharp Score. We found the frequency of EOA to be 6.3 in patients with RA. Erosive osteoarthritis was significantly higher in patients who had 50 years of age p 0.006, disease duration 10 years p 0.003, and anti-CCP negativity p 0.02 than in those without. In multivariable regression analysis, only age was the independent predictive factor for EOA p0.001 in RA patients. We published the frequency and associated risk factors of EOA in RA for the first time in literature. Rheumatologists should take EOA into account when making treatment decisions in middle agedelderly RA population. Further prospective studies are needed to explain the linkage between RA and EOA.

 Erosive osteoarthritis EOA is a deformative joint disease affecting small joints of hands that causes pain and disability, as does rheumatoid arthritis RA. So, EOA may interfere with the assessment of RA disease activity. In this study, we aimed to determine the frequency and associated factors of EOA in patients with RA and pay attention to the overlap syndrome between RA and EOA. The electronic medical files of adult RA patients were reviewed retrospectively. Patients with another rheumatic diseases were excluded. Hand X-rays were read by two rheumatologists and one radiologist. Patients with RA were divided into two groups according to the presence of EOA. We totally analyzed 619 patients with a mean age of 54.2 years, and 82.8 of them were female. The 95.4 of patients had RA-type erosive changes according to the Modified Sharp Score. We found the frequency of EOA to be 6.3 in patients with RA. Erosive osteoarthritis was significantly higher in patients who had 50 years of age p 0.006, disease duration 10 years p 0.003, and anti-CCP negativity p 0.02 than in those without. In multivariable regression analysis, only age was the independent predictive factor for EOA p0.001 in RA patients. We published the frequency and associated risk factors of EOA in RA for the first time in literature. Rheumatologists should take EOA into account when making treatment decisions in middle agedelderly RA population. Further prospective studies are needed to explain the linkage between RA and EOA.

Makale detayları

The frequency and associated factors of erosive osteoarthritis in patients with rheumatoid arthritis

Yazarlar: Mete Pekdiker | İnan Korkmaz | Sertaç Ketenci

Yayıncı: Ondokuz Mayıs University

Ana Başlıklar: Rheumatology and Arthritis

Dergi: Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 4, pp.733-737

Belge Tipi: Makale

Yayın Tarihi: 12/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001338251

pISSN: 1309-4483

erosive osteoarthritis

rheumatoid arthritis

risk factor

overlap syndrome

Sayı

Yazarlar:

Mete Pekdiker | İnan Korkmaz | Sertaç Ketenci

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Rheumatology and Arthritis

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 4, pp.733-737

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001338251

pISSN:

1309-4483