The comparison between propofol and dexmedetomidine infusion on perioperative  anxiety during regional anesthesia

Yong Peng LIM; Nurlia YAHYA; Azarinah IZAHAM; Esa KAMARUZAMAN; Muhammad Zurrusydi ZAINUDDIN; Wan Rahiza WAN MAT; Shereen Suet Ping TANG; Jaafar Md ZAIN; Siti Nidzwani MOHAMAD MAHDI

Makale detayları

The comparison between propofol and dexmedetomidine infusion on perioperative anxiety during regional anesthesia

Yazarlar:

Yong Peng LIM | Nurlia YAHYA | Azarinah IZAHAM | Esa KAMARUZAMAN | Muhammad Zurrusydi ZAINUDDIN | Wan Rahiza WAN MAT | Shereen Suet Ping TANG | Jaafar Md ZAIN | Siti Nidzwani MOHAMAD MAHDI

Yayıncı:

TUBITAK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Medical Sciences 2018 Vol.48 Issue 6, pp.1219-1227

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000750474

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 


 
                         Background/aim:
 Regional anesthesia for surgery is associated with increased anxiety for patients. This study aimed to compare the 
effect of propofol and dexmedetomidine infusion on perioperative anxiety during regional anesthesia.
Materials  and  methods:
  Eighty-four  patients  were  randomly  divided  into  two  groups  receiving  either  study  drug  infusion.  Anxiety  
score, level of sedation using the Bispectral Index and Observer's Assessment of Alertness and Sedation, hemodynamic stability, and 
overall patient's feedback on anxiolysis were assessed.
Results:
  Both  groups  showed  a  significant  drop  in  mean  anxiety  score  at  10  and  30  min  after  starting  surgery.  Difference  in  median  
anxiety scores showed a significant reduction in anxiety score at the end of the surgery in the dexmedetomidine group compared to the 
propofol group. Dexmedetomidine and propofol showed a significant drop in mean arterial pressure in the first 30 min and first 10 min 
respectively. Both drugs demonstrated a significant drop in heart rate in the first 20 min from baseline after starting the drug infusion. 
Patients in the dexmedetomidine group (76.20%) expressed statistically excellent feedback on anxiolysis compared to patients in the 
propofol group (45.20%). 
Conclusion:
 Dexmedetomidine infusion was found to significantly reduce anxiety levels at the end of surgery compared to propofol 
during regional anesthesia.
                    

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Makale detayları

The comparison between propofol and dexmedetomidine infusion on perioperative anxiety during regional anesthesia

Yazarlar: Yong Peng LIM | Nurlia YAHYA | Azarinah IZAHAM | Esa KAMARUZAMAN | Muhammad Zurrusydi ZAINUDDIN | Wan Rahiza WAN MAT | Shereen Suet Ping TANG | Jaafar Md ZAIN | Siti Nidzwani MOHAMAD MAHDI

Yayıncı: TUBITAK

Ana Başlıklar: Sağlık teşvikleri

Dergi: Turkish Journal of Medical Sciences 2018 Vol.48 Issue 6, pp.1219-1227

Belge Tipi: Makale

Yayın Tarihi: 12/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000750474

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Yong Peng LIM | Nurlia YAHYA | Azarinah IZAHAM | Esa KAMARUZAMAN | Muhammad Zurrusydi ZAINUDDIN | Wan Rahiza WAN MAT | Shereen Suet Ping TANG | Jaafar Md ZAIN | Siti Nidzwani MOHAMAD MAHDI

Yayıncı:

TUBITAK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Medical Sciences 2018 Vol.48 Issue 6, pp.1219-1227

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000750474

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144