Increased nitrite levels in exhaled breath condensate in asthma-like syndrome induced by occupational sulfur dioxide exposure*

Zeki YILDIRIM; Sadık SÖĞÜT; Nurhan KÖKSAL; Talat KILIÇ

Makale detayları

Increased nitrite levels in exhaled breath condensate in asthma-like syndrome induced by occupational sulfur dioxide exposure*

Yazarlar:

Zeki YILDIRIM | Sadık SÖĞÜT | Nurhan KÖKSAL | Talat KILIÇ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2012 Vol.42 Issue 3, pp.425-431

Belge Tipi:

Makale

Yayın Tarihi:

2/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000754157

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

To investigate whether nitrite levels were abnormally high in expired breath condensate (EBC) from workers with asthma-like syndrome.   Materials and methods: We measured the nitrite levels in EBC from 48 volunteer workers, including 25 smokers, with asthma-like syndrome before and after SO2 exposure and compared these levels with those from 44 nonexposed control subjects, including 23 smokers.   Results: Baseline concentrations of nitrite in the workers before SO2 exposure were higher (19.31 ± 1.06 nmol/mL) than in the controls (13.08 ± 1.36 nmol/mL; P  0.05).   Conclusion: We concluded that nitrite levels in EBC are increased in the asthma-like syndrome induced by occupational SO2 exposure in an agricultural environment, suggesting the role of inflammation in the syndrome; this first application of the EBC method may be suitable in other field studies in occupational medicine.

 

To investigate whether nitrite levels were abnormally high in expired breath condensate (EBC) from workers with asthma-like syndrome.   Materials and methods: We measured the nitrite levels in EBC from 48 volunteer workers, including 25 smokers, with asthma-like syndrome before and after SO2 exposure and compared these levels with those from 44 nonexposed control subjects, including 23 smokers.   Results: Baseline concentrations of nitrite in the workers before SO2 exposure were higher (19.31 ± 1.06 nmol/mL) than in the controls (13.08 ± 1.36 nmol/mL; P  0.05).   Conclusion: We concluded that nitrite levels in EBC are increased in the asthma-like syndrome induced by occupational SO2 exposure in an agricultural environment, suggesting the role of inflammation in the syndrome; this first application of the EBC method may be suitable in other field studies in occupational medicine.

Makale detayları

Increased nitrite levels in exhaled breath condensate in asthma-like syndrome induced by occupational sulfur dioxide exposure*

Yazarlar:

Zeki YILDIRIM | Sadık SÖĞÜT | Nurhan KÖKSAL | Talat KILIÇ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2012 Vol.42 Issue 3, pp.425-431

Belge Tipi:

Makale

Yayın Tarihi:

2/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000754157

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Key words: Nitrite

asthma-like syndrome

sulfur dioxide

agriculture

apricot sulfurization

Sayı

Makale detayları

Increased nitrite levels in exhaled breath condensate in asthma-like syndrome induced by occupational sulfur dioxide exposure*

Yazarlar: Zeki YILDIRIM | Sadık SÖĞÜT | Nurhan KÖKSAL | Talat KILIÇ

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2012 Vol.42 Issue 3, pp.425-431

Belge Tipi: Makale

Yayın Tarihi: 2/2012

Belge Dili: Türkçe

Document ID (Org No.): 2000754157

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Key words: Nitrite

asthma-like syndrome

sulfur dioxide

agriculture

apricot sulfurization

Sayı

Yazarlar:

Zeki YILDIRIM | Sadık SÖĞÜT | Nurhan KÖKSAL | Talat KILIÇ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2012 Vol.42 Issue 3, pp.425-431

Belge Tipi:

Makale

Yayın Tarihi:

2/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000754157

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144