The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis

Mehmet Karagülle; Fatma Zeynep Arslan; Mehmet Semih Çakır; Abdullah Soydan Mahmutoğlu; Ayşe İnci

Makale detayları

The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis

Yazarlar:

Mehmet Karagülle | Fatma Zeynep Arslan | Mehmet Semih Çakır | Abdullah Soydan Mahmutoğlu | Ayşe İnci

Yayıncı:

Selcuk University

Ana Başlıklar:

Radyoloji ve Organ Görüntüleme

Dergi:

Genel Tıp Dergisi Vol.34 Issue 1, pp.65-70

Belge Tipi:

Makale

Yayın Tarihi:

2/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001312228

pISSN:

2602-3741

Anahtar kelimeler:

Özet:

 Aim: We examined the relationship between shear wave elastography SWE values and histopathological results in our study. Thus, we found the sensitivity of SWE in demonstrating early fibrosis. Materials and Methods: A total of consecutive 70 patients with chronic hepatitis B were prospectively evaluated. The patients included in fibrosis stages F 0, 1, 2, 3 and 4 according to Ishak scoring were examined with SWE. SWE measurements of F2, F3 and F4 patients who were found to have early stage fibrosis were compared with those of F0 and F1 patients. Results: The velocitySD, and kPaSD values in the group requiring treatment F2, F3 and F4 were significantly higher than the group not requiring treatment F0 and F1 p  0.05. The sensitivity rate of the 1.85 cut-off value for velocitySD was 53.8, the positive prediction rate was 80.8, the specificity rate was 83.3, and the negative prediction rate was 58.1. For kPaSD, the cut-off value of 10.8 had a sensitivity rate of 51.3, a positive prediction rate of 95.2, a specificity of 96.7, and a negative predictive rate of 60.4. A significant correlation was observed between the fibrosis score and the kPaSD distribution. Conclusion: SWE can differentiate the patients requiring treatment F2, F3 and F4 from the patients not requiring treatment.

 Aim: We examined the relationship between shear wave elastography SWE values and histopathological results in our study. Thus, we found the sensitivity of SWE in demonstrating early fibrosis. Materials and Methods: A total of consecutive 70 patients with chronic hepatitis B were prospectively evaluated. The patients included in fibrosis stages F 0, 1, 2, 3 and 4 according to Ishak scoring were examined with SWE. SWE measurements of F2, F3 and F4 patients who were found to have early stage fibrosis were compared with those of F0 and F1 patients. Results: The velocitySD, and kPaSD values in the group requiring treatment F2, F3 and F4 were significantly higher than the group not requiring treatment F0 and F1 p  0.05. The sensitivity rate of the 1.85 cut-off value for velocitySD was 53.8, the positive prediction rate was 80.8, the specificity rate was 83.3, and the negative prediction rate was 58.1. For kPaSD, the cut-off value of 10.8 had a sensitivity rate of 51.3, a positive prediction rate of 95.2, a specificity of 96.7, and a negative predictive rate of 60.4. A significant correlation was observed between the fibrosis score and the kPaSD distribution. Conclusion: SWE can differentiate the patients requiring treatment F2, F3 and F4 from the patients not requiring treatment.

 Aim: We examined the relationship between shear wave elastography SWE values and histopathological results in our study. Thus, we found the sensitivity of SWE in demonstrating early fibrosis. Materials and Methods: A total of consecutive 70 patients with chronic hepatitis B were prospectively evaluated. The patients included in fibrosis stages F 0, 1, 2, 3 and 4 according to Ishak scoring were examined with SWE. SWE measurements of F2, F3 and F4 patients who were found to have early stage fibrosis were compared with those of F0 and F1 patients. Results: The velocitySD, and kPaSD values in the group requiring treatment F2, F3 and F4 were significantly higher than the group not requiring treatment F0 and F1 p  0.05. The sensitivity rate of the 1.85 cut-off value for velocitySD was 53.8, the positive prediction rate was 80.8, the specificity rate was 83.3, and the negative prediction rate was 58.1. For kPaSD, the cut-off value of 10.8 had a sensitivity rate of 51.3, a positive prediction rate of 95.2, a specificity of 96.7, and a negative predictive rate of 60.4. A significant correlation was observed between the fibrosis score and the kPaSD distribution. Conclusion: SWE can differentiate the patients requiring treatment F2, F3 and F4 from the patients not requiring treatment.

 Amaç: Çalışmamızda ultrason shear wave elastografi SWE değerleri ile histopatolojik sonuçlar arasındaki ilişkiyi inceledik. Böylece, SWEnin erken fibrozu göstermedeki duyarlılığını değerlendirdik. Materyal ve Metod: Kronik hepatit B hastalığına sahip ardışık 70 hasta prospektif olarak değerlendirildi. Ishak skorlamasına göre fibroz evreleri F 0, 1, 2, 3 ve 4e dahil edilen hastalar SWE ile incelendi. Erken evre fibroz tespit edilen F2, F3 ve F4 hastalarının SWE ölçümleri, tedavi gerektirmeyen F0 ve F1 hastalarının ölçümleri ile karşılaştırıldı. Bulgular: Tedavi gerektiren grup F2, F3 ve F4 içindeki hızSD ve kPaSD değerleri, tedavi gerektirmeyen grup F0 ve F1 içindeki değerlere göre anlamlı şekilde yüksekti p  0.05. HızSD için 1.85 kesme değerinin duyarlılık oranı 53.8, pozitif tahmin oranı 80.8, özgüllük oranı 83.3 ve negatif tahmin oranı 58.1 olarak bulundu. kPaSD için, 10.8 kesme değeri duyarlılık oranı 51.3, pozitif tahmin oranı 95.2, özgüllük oranı 96.7 ve negatif tahmin oranı 60.4 olarak saptandı. Fibroz skoru ile kPaSD dağılımı arasında anlamlı bir korelasyon gözlendi. Sonuç: KDE, tedavi gerektiren hastaları F2, F3 ve F4 tedavi gerektirmeyen hastalardan ayırt edebilir.

Makale detayları

The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis

Yazarlar:

Mehmet Karagülle | Fatma Zeynep Arslan | Mehmet Semih Çakır | Abdullah Soydan Mahmutoğlu | Ayşe İnci

Yayıncı:

Selcuk University

Ana Başlıklar:

Radyoloji ve Organ Görüntüleme

Dergi:

Genel Tıp Dergisi Vol.34 Issue 1, pp.65-70

Belge Tipi:

Makale

Yayın Tarihi:

2/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001312228

pISSN:

2602-3741

Sher Wave Elastgraphy

Liver

FibrosisShear Wave Elastografi

karaciğer

fibrozis

Sayı

Makale detayları

The Role of Shear Wave Elastography in Predicting Early Stage Liver Fibrosis

Yazarlar: Mehmet Karagülle | Fatma Zeynep Arslan | Mehmet Semih Çakır | Abdullah Soydan Mahmutoğlu | Ayşe İnci

Yayıncı: Selcuk University

Ana Başlıklar: Radyoloji ve Organ Görüntüleme

Dergi: Genel Tıp Dergisi Vol.34 Issue 1, pp.65-70

Belge Tipi: Makale

Yayın Tarihi: 2/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001312228

pISSN: 2602-3741

Sher Wave Elastgraphy

Liver

FibrosisShear Wave Elastografi

karaciğer

fibrozis

Sayı

Yazarlar:

Mehmet Karagülle | Fatma Zeynep Arslan | Mehmet Semih Çakır | Abdullah Soydan Mahmutoğlu | Ayşe İnci

Yayıncı:

Selcuk University

Ana Başlıklar:

Radyoloji ve Organ Görüntüleme

Dergi:

Genel Tıp Dergisi Vol.34 Issue 1, pp.65-70

Belge Tipi:

Makale

Yayın Tarihi:

2/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001312228

pISSN:

2602-3741