Evaluation of the biocompatibility of various self-adhesive resin cements on subcutaneous connective tissue: An in vivo study

Anıl Gerçek; Bilge Turhan Bal; Emre Barış

Makale detayları

Evaluation of the biocompatibility of various self-adhesive resin cements on subcutaneous connective tissue: An in vivo study

Yazarlar:

Anıl Gerçek | Bilge Turhan Bal | Emre Barış

Yayıncı:

Selcuk University

Ana Başlıklar:

Dentistry

Dergi:

Selcuk Dental Journal Vol.10 Issue 2, pp.429-433

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001294042

pISSN:

2148-7529

Anahtar kelimeler:

Özet:

 Background: The purpose of the study was to examine the subcutaneous connective tissue reaction to three self-adhesive resin cements. Methods: Sixty-three polyethylene tubes were filled with three different self-adhesive resin cements Group Z Zirconite, Group P Panavia SA, and Group H High Q Bond. Twenty-one polyethylene tubes remained empty and were used as controls Group C. All tubes were implanted into the subcutaneous tissue of the 21 rats. Specimens from each cement type were obtained at 7, 30, and 90 days. Quantitative assessments of inflammatory cells were performed in 5 different areas of each specimen. Results: All animals survive during the follow-up periods except two rats. The mean values of inflammatory cells at 90 days were 14 1.8, 15.1 3.5, 96 12.1, 16 2.1 in Groups C, H, P, and Z, respectively. The thicknesses of the fibrous capsule decreased significantly with time in all groups except Group P. Conclusion: Biocompatibility of self-adhesive resin cements was material-dependent. High Q Bond and Zirconite exhibited satisfactory biocompatibility; however, Panavia demonstrated a moderate inflammatory response at 90 days.

 Background: The purpose of the study was to examine the subcutaneous connective tissue reaction to three self-adhesive resin cements. Methods: Sixty-three polyethylene tubes were filled with three different self-adhesive resin cements Group Z Zirconite, Group P Panavia SA, and Group H High Q Bond. Twenty-one polyethylene tubes remained empty and were used as controls Group C. All tubes were implanted into the subcutaneous tissue of the 21 rats. Specimens from each cement type were obtained at 7, 30, and 90 days. Quantitative assessments of inflammatory cells were performed in 5 different areas of each specimen. Results: All animals survive during the follow-up periods except two rats. The mean values of inflammatory cells at 90 days were 14 1.8, 15.1 3.5, 96 12.1, 16 2.1 in Groups C, H, P, and Z, respectively. The thicknesses of the fibrous capsule decreased significantly with time in all groups except Group P. Conclusion: Biocompatibility of self-adhesive resin cements was material-dependent. High Q Bond and Zirconite exhibited satisfactory biocompatibility; however, Panavia demonstrated a moderate inflammatory response at 90 days.

 Background: The purpose of the study was to examine the subcutaneous connective tissue reaction to three self-adhesive resin cements. Methods: Sixty-three polyethylene tubes were filled with three different self-adhesive resin cements Group Z Zirconite, Group P Panavia SA, and Group H High Q Bond. Twenty-one polyethylene tubes remained empty and were used as controls Group C. All tubes were implanted into the subcutaneous tissue of the 21 rats. Specimens from each cement type were obtained at 7, 30, and 90 days. Quantitative assessments of inflammatory cells were performed in 5 different areas of each specimen. Results: All animals survive during the follow-up periods except two rats. The mean values of inflammatory cells at 90 days were 14 1.8, 15.1 3.5, 96 12.1, 16 2.1 in Groups C, H, P, and Z, respectively. The thicknesses of the fibrous capsule decreased significantly with time in all groups except Group P. Conclusion: Biocompatibility of self-adhesive resin cements was material-dependent. High Q Bond and Zirconite exhibited satisfactory biocompatibility; however, Panavia demonstrated a moderate inflammatory response at 90 days.

 Amaç: Bu calışmanın amacı üç farklı self adeziv rezin simana karşı gelişen subkutanöz doku reaksiyonunu incelemektir. Gereç ve Yöntemler: 63 adet polietilen tüp içine üç farklı self adeziv rezin siman yerleştirildi. Grup Z Zirconite, Grup P Panavia SA, and Grup H High Q Bond. 21 polietilen tüp boş bırakıldı ve kontrol grubu olarak kullanıldı Grup C. Bütün tüpler 21 adet farenin subkutanöz dokusuna yerleştirildi. Her siman tipinden subkutan olarak yerleştirilmiş siman örnekleri, 7, 30, 90. günlerde çıkartıldı. İnflamatuar hücrelerinin sayısal değerlendirmesi her örneğin 5 farklı alanından yapıldı. Bulgular: 2 fare dışında tüm hayvanlar takip periyodları boyunca canlı kaldı. 90. günde Grup C, H, P ve Z de enflamatuar hücrelerin ortalama değerleri sırasıyla 14 1.8, 15.1 3.5, 96 12.1, 16 2.1 şeklindedir. Panavya dışında tüm gruplarda fibröz kapsül kalınlığı zaman içinde anlamlı derecede azalmıştır. Sonuç: Self adesiv rezin simanların biyouyumluluğu materyale bağlı olarak farklılık göstermektedir. 90. Günde High Q Bond ve Zirconite yeterli biyouyumluluk değeri gösterirken Panavya siman da orta derecede inflamatuar cevap gözlemlenmiştir.

Makale detayları

Evaluation of the biocompatibility of various self-adhesive resin cements on subcutaneous connective tissue: An in vivo study

Yazarlar:

Anıl Gerçek | Bilge Turhan Bal | Emre Barış

Yayıncı:

Selcuk University

Ana Başlıklar:

Dentistry

Dergi:

Selcuk Dental Journal Vol.10 Issue 2, pp.429-433

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001294042

pISSN:

2148-7529

biocompatible materials

inflammation

resin cementsBiyouyumlu materyaller

enflamasyon

rezin simanlar

Sayı

Makale detayları

Evaluation of the biocompatibility of various self-adhesive resin cements on subcutaneous connective tissue: An in vivo study

Yazarlar: Anıl Gerçek | Bilge Turhan Bal | Emre Barış

Yayıncı: Selcuk University

Ana Başlıklar: Dentistry

Dergi: Selcuk Dental Journal Vol.10 Issue 2, pp.429-433

Belge Tipi: Makale

Yayın Tarihi: 8/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001294042

pISSN: 2148-7529

biocompatible materials

inflammation

resin cementsBiyouyumlu materyaller

enflamasyon

rezin simanlar

Sayı

Yazarlar:

Anıl Gerçek | Bilge Turhan Bal | Emre Barış

Yayıncı:

Selcuk University

Ana Başlıklar:

Dentistry

Dergi:

Selcuk Dental Journal Vol.10 Issue 2, pp.429-433

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001294042

pISSN:

2148-7529