Assessing the relationship between liver and spleen volumes in patients with liver cirrhosis using the Cavalieri principle on cross-sectional images

Merve Nur Özgen; Abdurrahman Şahin; Ruken Yuksekkaya; Bünyamin Şahin

Makale detayları

Assessing the relationship between liver and spleen volumes in patients with liver cirrhosis using the Cavalieri principle on cross-sectional images

Yazarlar:

Merve Nur Özgen | Abdurrahman Şahin | Ruken Yuksekkaya | Bünyamin Şahin

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Gastroenterology and Hepatology | Radiology and Organ Imaging

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 4, pp.738-745

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001338252

pISSN:

1309-4483

Anahtar kelimeler:

Özet:

 In the early stages of liver cirrhosis, hepatomegaly is observed, while in the later stages, enlargement of the spleen is observed due to shrinkage of the liver and increased pressure in the portal circulation. This study examined liver and spleen volumes and their proportional relationship to each other in healthy controls HC and patients with liver cirrhosis LC using computed tomography CT images. CT images of 52 LC 26 females, 26 males and 52 HC 26 females, 26 males aged 18 to 85 years were used. Liver and spleen volumes and spleenliverspleen volume ratio were calculated using the Cavalieri principle. Volume and ratio data were compared between HC and LC. In addition, volumes and ratios were evaluated according to the disease classes in patients. Liver volume was larger in LC 1488.9502.3 cm3 than in HC 1321.8277.1 cm3 p0.038. Spleen volume was also larger in LC 676.8347.02 cm3 than in HC 249.37101.16 cm3 p0.001. The spleenliverspleen volume ratio was higher in LC 30.7512.22 than in HC 15.685.09 p0.001. There was no difference in volume ratios between LC and HC according to sex p0.05. Liver volumes were 1670.7 cm3, 1357.4 cm3, and 1087.3 cm3, and the spleenliverspleen volume ratio were 26.71, 33.49, and 40.26 in classes A, B, and C of LC, respectively. As the cirrhosis class progressed, liver volume decreased p0.010, and the spleenliverspleen volume ratio increased p0.020. Liver and spleen sizes and the spleenliverspleen volume ratio did not change depending on sex. These values can be used as normal value parameters independent of sex. Liver and spleen volumes and ratios were larger in LC than in HC. As the class of cirrhosis progressed, liver volume decreased, and the ratio increased. Our findings suggest that the spleenliverspleen volume ratio can be used to evaluate the classes of liver cirrhosis.

 In the early stages of liver cirrhosis, hepatomegaly is observed, while in the later stages, enlargement of the spleen is observed due to shrinkage of the liver and increased pressure in the portal circulation. This study examined liver and spleen volumes and their proportional relationship to each other in healthy controls HC and patients with liver cirrhosis LC using computed tomography CT images. CT images of 52 LC 26 females, 26 males and 52 HC 26 females, 26 males aged 18 to 85 years were used. Liver and spleen volumes and spleenliverspleen volume ratio were calculated using the Cavalieri principle. Volume and ratio data were compared between HC and LC. In addition, volumes and ratios were evaluated according to the disease classes in patients. Liver volume was larger in LC 1488.9502.3 cm3 than in HC 1321.8277.1 cm3 p0.038. Spleen volume was also larger in LC 676.8347.02 cm3 than in HC 249.37101.16 cm3 p0.001. The spleenliverspleen volume ratio was higher in LC 30.7512.22 than in HC 15.685.09 p0.001. There was no difference in volume ratios between LC and HC according to sex p0.05. Liver volumes were 1670.7 cm3, 1357.4 cm3, and 1087.3 cm3, and the spleenliverspleen volume ratio were 26.71, 33.49, and 40.26 in classes A, B, and C of LC, respectively. As the cirrhosis class progressed, liver volume decreased p0.010, and the spleenliverspleen volume ratio increased p0.020. Liver and spleen sizes and the spleenliverspleen volume ratio did not change depending on sex. These values can be used as normal value parameters independent of sex. Liver and spleen volumes and ratios were larger in LC than in HC. As the class of cirrhosis progressed, liver volume decreased, and the ratio increased. Our findings suggest that the spleenliverspleen volume ratio can be used to evaluate the classes of liver cirrhosis.

 In the early stages of liver cirrhosis, hepatomegaly is observed, while in the later stages, enlargement of the spleen is observed due to shrinkage of the liver and increased pressure in the portal circulation. This study examined liver and spleen volumes and their proportional relationship to each other in healthy controls HC and patients with liver cirrhosis LC using computed tomography CT images. CT images of 52 LC 26 females, 26 males and 52 HC 26 females, 26 males aged 18 to 85 years were used. Liver and spleen volumes and spleenliverspleen volume ratio were calculated using the Cavalieri principle. Volume and ratio data were compared between HC and LC. In addition, volumes and ratios were evaluated according to the disease classes in patients. Liver volume was larger in LC 1488.9502.3 cm3 than in HC 1321.8277.1 cm3 p0.038. Spleen volume was also larger in LC 676.8347.02 cm3 than in HC 249.37101.16 cm3 p0.001. The spleenliverspleen volume ratio was higher in LC 30.7512.22 than in HC 15.685.09 p0.001. There was no difference in volume ratios between LC and HC according to sex p0.05. Liver volumes were 1670.7 cm3, 1357.4 cm3, and 1087.3 cm3, and the spleenliverspleen volume ratio were 26.71, 33.49, and 40.26 in classes A, B, and C of LC, respectively. As the cirrhosis class progressed, liver volume decreased p0.010, and the spleenliverspleen volume ratio increased p0.020. Liver and spleen sizes and the spleenliverspleen volume ratio did not change depending on sex. These values can be used as normal value parameters independent of sex. Liver and spleen volumes and ratios were larger in LC than in HC. As the class of cirrhosis progressed, liver volume decreased, and the ratio increased. Our findings suggest that the spleenliverspleen volume ratio can be used to evaluate the classes of liver cirrhosis.

 In the early stages of liver cirrhosis, hepatomegaly is observed, while in the later stages, enlargement of the spleen is observed due to shrinkage of the liver and increased pressure in the portal circulation. This study examined liver and spleen volumes and their proportional relationship to each other in healthy controls HC and patients with liver cirrhosis LC using computed tomography CT images. CT images of 52 LC 26 females, 26 males and 52 HC 26 females, 26 males aged 18 to 85 years were used. Liver and spleen volumes and spleenliverspleen volume ratio were calculated using the Cavalieri principle. Volume and ratio data were compared between HC and LC. In addition, volumes and ratios were evaluated according to the disease classes in patients. Liver volume was larger in LC 1488.9502.3 cm3 than in HC 1321.8277.1 cm3 p0.038. Spleen volume was also larger in LC 676.8347.02 cm3 than in HC 249.37101.16 cm3 p0.001. The spleenliverspleen volume ratio was higher in LC 30.7512.22 than in HC 15.685.09 p0.001. There was no difference in volume ratios between LC and HC according to sex p0.05. Liver volumes were 1670.7 cm3, 1357.4 cm3, and 1087.3 cm3, and the spleenliverspleen volume ratio were 26.71, 33.49, and 40.26 in classes A, B, and C of LC, respectively. As the cirrhosis class progressed, liver volume decreased p0.010, and the spleenliverspleen volume ratio increased p0.020. Liver and spleen sizes and the spleenliverspleen volume ratio did not change depending on sex. These values can be used as normal value parameters independent of sex. Liver and spleen volumes and ratios were larger in LC than in HC. As the class of cirrhosis progressed, liver volume decreased, and the ratio increased. Our findings suggest that the spleenliverspleen volume ratio can be used to evaluate the classes of liver cirrhosis.

Makale detayları

Assessing the relationship between liver and spleen volumes in patients with liver cirrhosis using the Cavalieri principle on cross-sectional images

Yazarlar:

Merve Nur Özgen | Abdurrahman Şahin | Ruken Yuksekkaya | Bünyamin Şahin

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Gastroenterology and Hepatology | Radiology and Organ Imaging

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 4, pp.738-745

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001338252

pISSN:

1309-4483

Liver

Spleen

Volume

Cirrhosis

Cavalieri principle

Computed tomography

Sayı

Makale detayları

Assessing the relationship between liver and spleen volumes in patients with liver cirrhosis using the Cavalieri principle on cross-sectional images

Yazarlar: Merve Nur Özgen | Abdurrahman Şahin | Ruken Yuksekkaya | Bünyamin Şahin

Yayıncı: Ondokuz Mayıs University

Ana Başlıklar: Gastroenterology and Hepatology | Radiology and Organ Imaging

Dergi: Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 4, pp.738-745

Belge Tipi: Makale

Yayın Tarihi: 12/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001338252

pISSN: 1309-4483

Liver

Spleen

Volume

Cirrhosis

Cavalieri principle

Computed tomography

Sayı

Yazarlar:

Merve Nur Özgen | Abdurrahman Şahin | Ruken Yuksekkaya | Bünyamin Şahin

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Gastroenterology and Hepatology | Radiology and Organ Imaging

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 4, pp.738-745

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001338252

pISSN:

1309-4483