In Vitro Antibacterial Studies of Ciprofloxacin-imines and Their Complexes with Cu(II),Ni(II),Co(II), and Zn(II)

Muhammad IMRAN; Javed IQBAL; Shahid IQBAL; Nazia IJAZ

Makale detayları

In Vitro Antibacterial Studies of Ciprofloxacin-imines and Their Complexes with Cu(II),Ni(II),Co(II), and Zn(II)

Yazarlar:

Muhammad IMRAN | Javed IQBAL | Shahid IQBAL | Nazia IJAZ

Yayıncı:

TUBITAK

Ana Başlıklar:

Yaşam bilimleri

Dergi:

Turkish Journal of Biology 2007 Vol.31 Issue 2, pp.67-72

Belge Tipi:

Makale

Yayın Tarihi:

1/2007

Belge Dili:

İngilizce

Document ID (Org No.):

2000813279

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Anahtar kelimeler:

Özet:

 

Some new transition metal complexes of ciprofloxacin-imines derived from ciprofloxacin and p-substituted anilines were synthesized and characterized on the basis of physical properties, conductance measurements, elemental analysis, UV/Vis., infrared and nuclear magnetic resonance spectroscopy. These ligands as well as their metal complexes were also evaluated for their antibacterial activity against several bacterial strains, such as Staphylococcus aureus, Bacillus subtilus, Salmonella typhae, and E. coli. It was found that metal complexes are more antibacterial as compared to uncomplexed ligands. The present study was carried out in search of a target antibiotic instead of a broad spectrum one.

 

Some new transition metal complexes of ciprofloxacin-imines derived from ciprofloxacin and p-substituted anilines were synthesized and characterized on the basis of physical properties, conductance measurements, elemental analysis, UV/Vis., infrared and nuclear magnetic resonance spectroscopy. These ligands as well as their metal complexes were also evaluated for their antibacterial activity against several bacterial strains, such as Staphylococcus aureus, Bacillus subtilus, Salmonella typhae, and E. coli. It was found that metal complexes are more antibacterial as compared to uncomplexed ligands. The present study was carried out in search of a target antibiotic instead of a broad spectrum one.

Makale detayları

In Vitro Antibacterial Studies of Ciprofloxacin-imines and Their Complexes with Cu(II),Ni(II),Co(II), and Zn(II)

Yazarlar:

Muhammad IMRAN | Javed IQBAL | Shahid IQBAL | Nazia IJAZ

Yayıncı:

TUBITAK

Ana Başlıklar:

Yaşam bilimleri

Dergi:

Turkish Journal of Biology 2007 Vol.31 Issue 2, pp.67-72

Belge Tipi:

Makale

Yayın Tarihi:

1/2007

Belge Dili:

İngilizce

Document ID (Org No.):

2000813279

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Ciprofloxacin imines

coordination compounds

antibacterial activity

Sayı

Makale detayları

In Vitro Antibacterial Studies of Ciprofloxacin-imines and Their Complexes with Cu(II),Ni(II),Co(II), and Zn(II)

Yazarlar: Muhammad IMRAN | Javed IQBAL | Shahid IQBAL | Nazia IJAZ

Yayıncı: TUBITAK

Ana Başlıklar: Yaşam bilimleri

Dergi: Turkish Journal of Biology 2007 Vol.31 Issue 2, pp.67-72

Belge Tipi: Makale

Yayın Tarihi: 1/2007

Belge Dili: İngilizce

Document ID (Org No.): 2000813279

Sıklık: İki Aylık

eISSN: 1303-6092

pISSN: 1300-0152

Ciprofloxacin imines

coordination compounds

antibacterial activity

Sayı

Yazarlar:

Muhammad IMRAN | Javed IQBAL | Shahid IQBAL | Nazia IJAZ

Yayıncı:

TUBITAK

Ana Başlıklar:

Yaşam bilimleri

Dergi:

Turkish Journal of Biology 2007 Vol.31 Issue 2, pp.67-72

Belge Tipi:

Makale

Yayın Tarihi:

1/2007

Belge Dili:

İngilizce

Document ID (Org No.):

2000813279

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152