The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin

Hayati Demiraslan; Zeynep Ture; Aysegul Ulu Kılıc

doi:https://doi.org/10.5799/ahinjs.02.2012.03.0056

Makale detayları

The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin

Yazarlar:

Hayati Demiraslan | Zeynep Ture | Aysegul Ulu Kılıc

Yayıncı:

Sağlık Araştırmaları Derneği

Dergi:

Journal of Microbiology and Infectious Diseases 2012 Vol.2 Issue 03, pp.121-123

Belge Tipi:

Makale

Yayın Tarihi:

8/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000488018

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/ahinjs.02.2012.03.0056

Özet:

 

Hayati Demiraslan, Zeynep Ture, Aysegul Ulu Kılıc 			  	     	The pegylated interferon alpha and ribavirin treatment is well established therapy for hepatitis C virus (HCV) infection.     	During the treatment alanine aminotransferase (ALT) lare may be observed rarely.    	A 51-year-old female receiving pegylated interferon and ribavirin therapy for HCV infection, complained nausea, vomit-    	ing in seventh week of the therapy, and her ALT level was detected over 20 times above the normal level. Hepatitis B sur-    	face antigen, anti-nuclear antibody, anti-mitochondrial antibody, anti-double stranded DNA antibody and anti-hepatitis     	A virus IgM antibody were negative, and thyroid stimulating hormone was normal. HCV RNA level was 424 IU/ml. PEG     	IFN and ribavirin therapy was interrupted for three weeks, after liver enzyme level was detected less than 100U/L, the     	treatment was resumed. The patient was followed up for 2 months, ALT lare was not observed.    	In  conclusion, we present  a  rare  case with ALT  lare, while  receiving pegylated  interferon  and  ribavirin  therapy  for     	chronic HCV infection.

Makale detayları

The acute hepatic flare in a patient with chronic hepatitis C infection receiving pegylated interferon alpha 2b and ribavirin

Yazarlar: Hayati Demiraslan | Zeynep Ture | Aysegul Ulu Kılıc

Yayıncı: Sağlık Araştırmaları Derneği

Dergi: Journal of Microbiology and Infectious Diseases 2012 Vol.2 Issue 03, pp.121-123

Belge Tipi: Makale

Yayın Tarihi: 8/2012

Belge Dili: İngilizce

Document ID (Org No.): 2000488018

Sıklık: Üç Aylık

eISSN: 2146-9369

pISSN: 2146-3158

DOI: https://doi.org/10.5799/ahinjs.02.2012.03.0056

Sayı

Yazarlar:

Hayati Demiraslan | Zeynep Ture | Aysegul Ulu Kılıc

Yayıncı:

Sağlık Araştırmaları Derneği

Dergi:

Journal of Microbiology and Infectious Diseases 2012 Vol.2 Issue 03, pp.121-123

Belge Tipi:

Makale

Yayın Tarihi:

8/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000488018

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/ahinjs.02.2012.03.0056