The Relationship Between Serum Lipids and Coronary Artery Disease in Patients Aged 85 and Over

Ali Osman Avcı

Makale detayları

The Relationship Between Serum Lipids and Coronary Artery Disease in Patients Aged 85 and Over

Yazarlar:

Ali Osman Avcı

Yayıncı:

Akdeniz University

Ana Başlıklar:

İç Hastalıkları

Dergi:

Akdeniz Tıp Dergisi Vol.10 Issue 3, pp.550-557

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001326475

pISSN:

2687-2781

Anahtar kelimeler:

Özet:

 Objective: The aim of this study is to investigate the relationship between serum low-density lipoprotein cholesterol LDL-C level and coronary artery disease CAD in patients aged 85 and over in our country. Material and Methods: This study was conducted retrospectively by scanning the patient files of those aged 85 and over who were admitted to the hospital between January 2020 and July 2023. Serum lipid profiles of patients diagnosed with CAD and patients without CAD were examined. Serum lipid concentrations of the patients were measured with Cobas 501. Statistical analysis was done with SPSS. Variables were tested for normal distribution with the Kolmogorov Smirnov test. Mann-Whitney U test was used for comparisons. A value of p0.05 was considered statistically significant. Results: A total of 726 patients were included in the study, 433 of whom were female 59.6 and 293 were male 40.4. Patients were divided into three groups according to LDL-C level. CAD was detected in 277 of 726 patients 38.2. Of those with CAD, 142 are female 51.3 and 135 are male 48.7. Conclusion: CAD increases with age, independent of serum lipid levels. In terms of CAD frequency, the ratio between men and women becomes approximately equal in older ages. It was observed that there was no statistically significant relationship between serum lipid levels, especially LDL-C, and CAD disease.

 Objective: The aim of this study is to investigate the relationship between serum low-density lipoprotein cholesterol LDL-C level and coronary artery disease CAD in patients aged 85 and over in our country. Material and Methods: This study was conducted retrospectively by scanning the patient files of those aged 85 and over who were admitted to the hospital between January 2020 and July 2023. Serum lipid profiles of patients diagnosed with CAD and patients without CAD were examined. Serum lipid concentrations of the patients were measured with Cobas 501. Statistical analysis was done with SPSS. Variables were tested for normal distribution with the Kolmogorov Smirnov test. Mann-Whitney U test was used for comparisons. A value of p0.05 was considered statistically significant. Results: A total of 726 patients were included in the study, 433 of whom were female 59.6 and 293 were male 40.4. Patients were divided into three groups according to LDL-C level. CAD was detected in 277 of 726 patients 38.2. Of those with CAD, 142 are female 51.3 and 135 are male 48.7. Conclusion: CAD increases with age, independent of serum lipid levels. In terms of CAD frequency, the ratio between men and women becomes approximately equal in older ages. It was observed that there was no statistically significant relationship between serum lipid levels, especially LDL-C, and CAD disease.

 Objective: The aim of this study is to investigate the relationship between serum low-density lipoprotein cholesterol LDL-C level and coronary artery disease CAD in patients aged 85 and over in our country. Material and Methods: This study was conducted retrospectively by scanning the patient files of those aged 85 and over who were admitted to the hospital between January 2020 and July 2023. Serum lipid profiles of patients diagnosed with CAD and patients without CAD were examined. Serum lipid concentrations of the patients were measured with Cobas 501. Statistical analysis was done with SPSS. Variables were tested for normal distribution with the Kolmogorov Smirnov test. Mann-Whitney U test was used for comparisons. A value of p0.05 was considered statistically significant. Results: A total of 726 patients were included in the study, 433 of whom were female 59.6 and 293 were male 40.4. Patients were divided into three groups according to LDL-C level. CAD was detected in 277 of 726 patients 38.2. Of those with CAD, 142 are female 51.3 and 135 are male 48.7. Conclusion: CAD increases with age, independent of serum lipid levels. In terms of CAD frequency, the ratio between men and women becomes approximately equal in older ages. It was observed that there was no statistically significant relationship between serum lipid levels, especially LDL-C, and CAD disease.

 Amaç: Bu çalışmanın amacı ülkemizdeki 85 yaş ve üstü hastalarda serum düşük dansiteli lipoprotein kolesterol LDL-K seviyesi ile koroner arter hastalığı KAH arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntem: Bu çalışma retrospektif olarak Ocak 2020-Temmuz 2023 tarihleri arasında hastaneye kabul edilen 85 yaş ve üzerinde olanların hasta dosyaları taranarak yapılmıştır. KAH tanısı konulan hastalar ile KAH tanısı olmayan hastaların serum lipid profilleri incelenmiştir. Hastaların serum lipid konsantrasyonları Cobas 501 ile ölçüldü. İstatiksel analiz SPSS ile yapıldı. Normal dağılım için değişkenler Kolmogorov Smirnov testi ile test edildi. Karşılaştırmalar için Mann-Whitney U testi kullanıldı. p0.05 değeri istatistiksel olarak anlamlı kabul edildi. Bulgular: Çalışmaya toplam 726 hasta alınmış olup bunların 433ü kadın  59,6 293ü erkek  40,4 hastalardan oluşmaktadır. Hastalar LDL-K seviyesine göre üç gruba ayrıldı. Toplam 726 hastanın 277sinde  38,2 KAH saptanmıştır. KAH olanların 142si kadın  51,3, 135i erkek  48,7 hastadır. Sonuç: KAH, serum lipid düzeylerinden bağımsız olarak yaşla birlikte artmaktadır. İleri yaşta KAH sıklığı açısından kadın-erkek oranı yaklaşık olarak eşit hale gelmektedir. Serum lipid seviyeleri ve özellikle LDL-K ile KAH hastalığı arasında istatistiksel olarak anlamlı bir ilişki olmadığı görülmüştür.

Makale detayları

The Relationship Between Serum Lipids and Coronary Artery Disease in Patients Aged 85 and Over

Yazarlar:

Ali Osman Avcı

Yayıncı:

Akdeniz University

Ana Başlıklar:

İç Hastalıkları

Dergi:

Akdeniz Tıp Dergisi Vol.10 Issue 3, pp.550-557

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001326475

pISSN:

2687-2781

85 years and above

coronary artery disease

LDL

HDL

TC

TG85 yaş ve üzeri

koronrer arter hastalığı

LDL

HDL

TK

TG

Sayı

Makale detayları

Yazarlar: Ali Osman Avcı

Yayıncı: Akdeniz University

Ana Başlıklar: İç Hastalıkları

Dergi: Akdeniz Tıp Dergisi Vol.10 Issue 3, pp.550-557

Belge Tipi: Makale

Yayın Tarihi: 9/2024

Belge Dili: Türkçe

Document ID (Org No.): 2001326475

pISSN: 2687-2781

Sayı

Yazarlar:

Ali Osman Avcı

Yayıncı:

Akdeniz University

Ana Başlıklar:

İç Hastalıkları

Dergi:

Akdeniz Tıp Dergisi Vol.10 Issue 3, pp.550-557

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001326475

pISSN:

2687-2781