Osteopenia in Newborns with Spinal Canal Defects

Sevdet Balık; Nilufer Okur; Leyla Şero; Duygu Tunçel; Muhammet Asena

Makale detayları

Osteopenia in Newborns with Spinal Canal Defects

Yazarlar:

Sevdet Balık | Nilufer Okur | Leyla Şero | Duygu Tunçel | Muhammet Asena

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Yoğun Bakım

Dergi:

Ahi Evran Tıp Dergisi Vol.8 Issue 3, pp.371-375

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001330302

pISSN:

2619-9203

Anahtar kelimeler:

Özet:

 Purpose: Fracture development is one of the complications in patients with spina bifida, with an incidence ranging from 11 to 30. This study aimed to investigate the frequency of fractures, osteopenia, and the factors associated with these conditions in neonates with spina bifida followed at our hospital. Materials and Methods: Cases who were hospitalized and operated on in our neonatal intensive care unit with the diagnosis of meningomyelocele MMS between 01 December 2020 and 31 January 2023 constituted the study group and were evaluated retrospectively. Perinatal findings gender, mode of delivery, gestational week, birth weight, operation time, postoperative sepsis, additional accompanying anomalies, length of stay, serum free thyroxine fT4 and thyroid stimulating hormone TSH levels were examined and recorded from the patient files. Results: A total of 89 neonates with MMS and encephalocele were evaluated. The median birth weight was 3000 g range: 1800-4300 g, and the median gestational age was 38 weeks range: 32-40 weeks. Hypocalcemia was present in 14 15.7 patients. One patient had a phosphorus level below 4 mgdl. All infants had normal alkaline phosphatase levels. Fractures were observed in 5 5.6 patients, all of whom had paralysis in the lower extremities. Conclusion: There are many risk factors for fracture development in children with spina bifida, and fractures can often be overlooked due to low ambulation capacity and sensory deficits. Close monitoring of bone quality and fracture development in these infants, along with medical treatment support when necessary, is recommended.

 Purpose: Fracture development is one of the complications in patients with spina bifida, with an incidence ranging from 11 to 30. This study aimed to investigate the frequency of fractures, osteopenia, and the factors associated with these conditions in neonates with spina bifida followed at our hospital. Materials and Methods: Cases who were hospitalized and operated on in our neonatal intensive care unit with the diagnosis of meningomyelocele MMS between 01 December 2020 and 31 January 2023 constituted the study group and were evaluated retrospectively. Perinatal findings gender, mode of delivery, gestational week, birth weight, operation time, postoperative sepsis, additional accompanying anomalies, length of stay, serum free thyroxine fT4 and thyroid stimulating hormone TSH levels were examined and recorded from the patient files. Results: A total of 89 neonates with MMS and encephalocele were evaluated. The median birth weight was 3000 g range: 1800-4300 g, and the median gestational age was 38 weeks range: 32-40 weeks. Hypocalcemia was present in 14 15.7 patients. One patient had a phosphorus level below 4 mgdl. All infants had normal alkaline phosphatase levels. Fractures were observed in 5 5.6 patients, all of whom had paralysis in the lower extremities. Conclusion: There are many risk factors for fracture development in children with spina bifida, and fractures can often be overlooked due to low ambulation capacity and sensory deficits. Close monitoring of bone quality and fracture development in these infants, along with medical treatment support when necessary, is recommended.

 Purpose: Fracture development is one of the complications in patients with spina bifida, with an incidence ranging from 11 to 30. This study aimed to investigate the frequency of fractures, osteopenia, and the factors associated with these conditions in neonates with spina bifida followed at our hospital. Materials and Methods: Cases who were hospitalized and operated on in our neonatal intensive care unit with the diagnosis of meningomyelocele MMS between 01 December 2020 and 31 January 2023 constituted the study group and were evaluated retrospectively. Perinatal findings gender, mode of delivery, gestational week, birth weight, operation time, postoperative sepsis, additional accompanying anomalies, length of stay, serum free thyroxine fT4 and thyroid stimulating hormone TSH levels were examined and recorded from the patient files. Results: A total of 89 neonates with MMS and encephalocele were evaluated. The median birth weight was 3000 g range: 1800-4300 g, and the median gestational age was 38 weeks range: 32-40 weeks. Hypocalcemia was present in 14 15.7 patients. One patient had a phosphorus level below 4 mgdl. All infants had normal alkaline phosphatase levels. Fractures were observed in 5 5.6 patients, all of whom had paralysis in the lower extremities. Conclusion: There are many risk factors for fracture development in children with spina bifida, and fractures can often be overlooked due to low ambulation capacity and sensory deficits. Close monitoring of bone quality and fracture development in these infants, along with medical treatment support when necessary, is recommended.

 Amaç: Kırık gelişimi; spina bifidalı hastalarda komplikasyonlardan biri olup, görülme oranı  11-30 arasında değişmektedir. Bu çalışmada hastanemizde takipli spina bifidalı yenidoğanlarda; kırık sıklığı, osteopeni ve bu durumla ilişkili faktörlerin araştırılması amaçlandı. Araçlar ve Yöntem: Bu çalışmada 01 Aralık 2020 ile 31 Ocak 2023 tarihleri arasında yenidoğan yoğun bakım ünitemize meningomyelosel MMS tanısıyla yatırılarak opere edilen olgular çalışma grubunu oluşturmuş ve retrospektif olarak değerlendirilmiştir. Perinatal bulgular cinsiyet, doğum şekli, gestasyonel hafta, doğum ağırlığı, operasyon zamanı, operasyon sonrası sepsis, eşlik eden ek anomaliler, yatış süresi, serum serbest tiroksin fT4 ve tiroid stimüle edici hormon TSH düzeyleri hasta dosyalarından incelendi ve kaydedildi. Bulgular: Toplam 89 MMS ve ensefaloselli yenidoğan bebeğin verileri değerlendirildi. Doğum ağırlıkları median 3000 gr min 1800-max 4300 gr ve gestasyon haftası 38 min 32- max 40tı. 14 15.7 hastada hipokalsemi vardı. Bir hastada fosfor düzeyi 4 mgdlün altındaydı. Tüm bebeklerin alkalen fosfataz düzeyleri normaldi. 5 5.6 hastada ekstremitelerde kırık vardı. Kırık saptanan bebeklerin tamamında alt ekstremitede paralizi mevcuttu. Sonuç: Spina bifidalı çocuklarda kırık gelişimi için pek çok risk faktörü bulunmakta olup düşük ambulasyon kapasitesi ve duyu defisiti nedeniyle kırıklar kolaylıkla gözden kaçabilmektedir. Bu bebeklerin kemik kalitesi ve kırık gelişimi açısından yakın takibi ve gerektiğinde medikal tedavi desteği önerilmektedir.

Makale detayları

Osteopenia in Newborns with Spinal Canal Defects

Yazarlar:

Sevdet Balık | Nilufer Okur | Leyla Şero | Duygu Tunçel | Muhammet Asena

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Yoğun Bakım

Dergi:

Ahi Evran Tıp Dergisi Vol.8 Issue 3, pp.371-375

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001330302

pISSN:

2619-9203

fracture

meningomyelocele

newbornkırık

meningomiyelosel

yenidoğan

Sayı

Makale detayları

Osteopenia in Newborns with Spinal Canal Defects

Yazarlar: Sevdet Balık | Nilufer Okur | Leyla Şero | Duygu Tunçel | Muhammet Asena

Yayıncı: Kirsehir Ahi Evran University

Ana Başlıklar: Yoğun Bakım

Dergi: Ahi Evran Tıp Dergisi Vol.8 Issue 3, pp.371-375

Belge Tipi: Makale

Yayın Tarihi: 12/2024

Belge Dili: Türkçe

Document ID (Org No.): 2001330302

pISSN: 2619-9203

fracture

meningomyelocele

newbornkırık

meningomiyelosel

yenidoğan

Sayı

Yazarlar:

Sevdet Balık | Nilufer Okur | Leyla Şero | Duygu Tunçel | Muhammet Asena

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Yoğun Bakım

Dergi:

Ahi Evran Tıp Dergisi Vol.8 Issue 3, pp.371-375

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001330302

pISSN:

2619-9203