Azadirachta indica leaf extract: Phytochemical composition and antioxidant, antibacterial, and antifungal activities

Wassima Lakhdari; Salah Neghmouche Nacer; Moussaoui Younes

Makale detayları

Azadirachta indica leaf extract: Phytochemical composition and antioxidant, antibacterial, and antifungal activities

Yazarlar:

Wassima Lakhdari | Salah Neghmouche Nacer | Moussaoui Younes

Yayıncı:

İzzet KARA

Ana Başlıklar:

Natural Products and Bioactive Compounds

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.615-629

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350178

pISSN:

2148-6905

Anahtar kelimeler:

Özet:

 The chemical components and natural traits of Azadirachta indica A. Juss. leaf extract from arid environments has been studied. LC-MS analysis identified quercetin, oleanolic acid, salicin, and catechin among the many bioactive compounds in the sample. It was observed that at a concentration of 25.01  0.71 µgmL, DPPH exhibited antioxidant activity with an IC50 value that is higher than that of β-carotene bleaching 22.29  0.66 µgmL, ABTS assay 45.09  1.23 µgmL, respectively. Bacillussubtilis, Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa showed susceptibility to the extract, with MICs ranging from VHC to 30 mgmL while Alternaria sp., Fusarium solani, and Thielaviopsis paradox represent the fungal strains tested for their sensitivity to this extract. Therefore, Azadirachta indica leaf extract from dry regions exhibits significant effects, potentially explaining its traditional use in medicine and agriculture.

 The chemical components and natural traits of Azadirachta indica A. Juss. leaf extract from arid environments has been studied. LC-MS analysis identified quercetin, oleanolic acid, salicin, and catechin among the many bioactive compounds in the sample. It was observed that at a concentration of 25.01  0.71 µgmL, DPPH exhibited antioxidant activity with an IC50 value that is higher than that of β-carotene bleaching 22.29  0.66 µgmL, ABTS assay 45.09  1.23 µgmL, respectively. Bacillussubtilis, Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa showed susceptibility to the extract, with MICs ranging from VHC to 30 mgmL while Alternaria sp., Fusarium solani, and Thielaviopsis paradox represent the fungal strains tested for their sensitivity to this extract. Therefore, Azadirachta indica leaf extract from dry regions exhibits significant effects, potentially explaining its traditional use in medicine and agriculture.

 The chemical components and natural traits of Azadirachta indica A. Juss. leaf extract from arid environments has been studied. LC-MS analysis identified quercetin, oleanolic acid, salicin, and catechin among the many bioactive compounds in the sample. It was observed that at a concentration of 25.01  0.71 µgmL, DPPH exhibited antioxidant activity with an IC50 value that is higher than that of β-carotene bleaching 22.29  0.66 µgmL, ABTS assay 45.09  1.23 µgmL, respectively. Bacillussubtilis, Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa showed susceptibility to the extract, with MICs ranging from VHC to 30 mgmL while Alternaria sp., Fusarium solani, and Thielaviopsis paradox represent the fungal strains tested for their sensitivity to this extract. Therefore, Azadirachta indica leaf extract from dry regions exhibits significant effects, potentially explaining its traditional use in medicine and agriculture.

 The chemical components and natural traits of Azadirachta indica A. Juss. leaf extract from arid environments has been studied. LC-MS analysis identified quercetin, oleanolic acid, salicin, and catechin among the many bioactive compounds in the sample. It was observed that at a concentration of 25.01  0.71 µgmL, DPPH exhibited antioxidant activity with an IC50 value that is higher than that of β-carotene bleaching 22.29  0.66 µgmL, ABTS assay 45.09  1.23 µgmL, respectively. Bacillussubtilis, Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa showed susceptibility to the extract, with MICs ranging from VHC to 30 mgmL while Alternaria sp., Fusarium solani, and Thielaviopsis paradox represent the fungal strains tested for their sensitivity to this extract. Therefore, Azadirachta indica leaf extract from dry regions exhibits significant effects, potentially explaining its traditional use in medicine and agriculture.

Makale detayları

Azadirachta indica leaf extract: Phytochemical composition and antioxidant, antibacterial, and antifungal activities

Yazarlar:

Wassima Lakhdari | Salah Neghmouche Nacer | Moussaoui Younes

Yayıncı:

İzzet KARA

Ana Başlıklar:

Natural Products and Bioactive Compounds

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.615-629

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350178

pISSN:

2148-6905

Azadirachtaindica

Phytochemical composition

Antioxidant

Antibacterial

AntifungalAzadirachtaindica

Phytochemical composition

Antioxidant

Antibacterial

Antifungal

Sayı

Makale detayları

Yazarlar: Wassima Lakhdari | Salah Neghmouche Nacer | Moussaoui Younes

Yayıncı: İzzet KARA

Ana Başlıklar: Natural Products and Bioactive Compounds

Dergi: International Journal of Secondary Metabolite Vol.12 Issue 3, pp.615-629

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001350178

pISSN: 2148-6905

Sayı

Yazarlar:

Wassima Lakhdari | Salah Neghmouche Nacer | Moussaoui Younes

Yayıncı:

İzzet KARA

Ana Başlıklar:

Natural Products and Bioactive Compounds

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.615-629

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350178

pISSN:

2148-6905