Comparative retrospective analysis of patients with idiopathic normal pressure hydrocephalus and aqueductal web-related aqueductal stenosis.

Alper Türkkan; Pınar Eser Ocak; Oğuz Altunyuva; Buket Sönmez; Rifat Özpar; Ahmet Bekar

Makale detayları

Comparative retrospective analysis of patients with idiopathic normal pressure hydrocephalus and aqueductal web-related aqueductal stenosis.

Yazarlar:

Alper Türkkan | Pınar Eser Ocak | Oğuz Altunyuva | Buket Sönmez | Rifat Özpar | Ahmet Bekar

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Brain and Nerve Surgery (Neurosurgery)

Dergi:

The European Research Journal Vol.9 Issue 6, pp.1464-1473

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001294107

pISSN:

2149-3189

Anahtar kelimeler:

Özet:

 Objectives: Aquaductal web AW is a special form of aqueductal stenosis with similar clinical presentation with idiopathic normal pressure hydrocephalus iNPH. iNPH is indeed a communicating hydrocephalus syndrome whereas AW is a noncommunicating subtype. Here, we aimed to investigate the similarities and differences between these two different chronic hydrocephalus syndromes in terms of clinical signs and symptoms, response to shunt treatment and postoperative complications. Methods: Forty-one patients who underwent shunt operation with the diagnosis of iNPH or AW at our clinic between January 2010-May 2019 were retrospectively analyzed. Patients were evaluated by age, gender, clinical sign and symptoms, comorbidities, intraoperative and postoperative complications, and early and late postoperative outpatient follow-up findings. Results: Twenty-six patients were classified as iNPH group and 15 patients as AW group. Patients in the AW group were significantly younger 45.5  15.6 years vs. 60.3  15.4 years than the iNPH group  p  0.006. There was no statistical difference between the groups in terms of subdural effusion formation, need for shunt revision  p  1.000. Chronic hydrocephalus symptoms regressed in 23 88.5 patients in the NPH group, and at least one of them improved. symptoms. This rate was 66.7 n  10 in the AW group. Both groups showed similar clinical improvement with VPS  p  0.1169. Conclusions: The placement of ventriculoperitoenal shunt is widely used in the treatment of iNPH. As iNPH and AW has clinical similarities despite the discrepancies between underlying pathophysiological mechanisms and both clinical entities respond similarly to shunt treatment we advocate VPS surgery in the management of AW as well.

 Objectives: Aquaductal web AW is a special form of aqueductal stenosis with similar clinical presentation with idiopathic normal pressure hydrocephalus iNPH. iNPH is indeed a communicating hydrocephalus syndrome whereas AW is a noncommunicating subtype. Here, we aimed to investigate the similarities and differences between these two different chronic hydrocephalus syndromes in terms of clinical signs and symptoms, response to shunt treatment and postoperative complications. Methods: Forty-one patients who underwent shunt operation with the diagnosis of iNPH or AW at our clinic between January 2010-May 2019 were retrospectively analyzed. Patients were evaluated by age, gender, clinical sign and symptoms, comorbidities, intraoperative and postoperative complications, and early and late postoperative outpatient follow-up findings. Results: Twenty-six patients were classified as iNPH group and 15 patients as AW group. Patients in the AW group were significantly younger 45.5  15.6 years vs. 60.3  15.4 years than the iNPH group  p  0.006. There was no statistical difference between the groups in terms of subdural effusion formation, need for shunt revision  p  1.000. Chronic hydrocephalus symptoms regressed in 23 88.5 patients in the NPH group, and at least one of them improved. symptoms. This rate was 66.7 n  10 in the AW group. Both groups showed similar clinical improvement with VPS  p  0.1169. Conclusions: The placement of ventriculoperitoenal shunt is widely used in the treatment of iNPH. As iNPH and AW has clinical similarities despite the discrepancies between underlying pathophysiological mechanisms and both clinical entities respond similarly to shunt treatment we advocate VPS surgery in the management of AW as well.

 Objectives: Aquaductal web AW is a special form of aqueductal stenosis with similar clinical presentation with idiopathic normal pressure hydrocephalus iNPH. iNPH is indeed a communicating hydrocephalus syndrome whereas AW is a noncommunicating subtype. Here, we aimed to investigate the similarities and differences between these two different chronic hydrocephalus syndromes in terms of clinical signs and symptoms, response to shunt treatment and postoperative complications. Methods: Forty-one patients who underwent shunt operation with the diagnosis of iNPH or AW at our clinic between January 2010-May 2019 were retrospectively analyzed. Patients were evaluated by age, gender, clinical sign and symptoms, comorbidities, intraoperative and postoperative complications, and early and late postoperative outpatient follow-up findings. Results: Twenty-six patients were classified as iNPH group and 15 patients as AW group. Patients in the AW group were significantly younger 45.5  15.6 years vs. 60.3  15.4 years than the iNPH group  p  0.006. There was no statistical difference between the groups in terms of subdural effusion formation, need for shunt revision  p  1.000. Chronic hydrocephalus symptoms regressed in 23 88.5 patients in the NPH group, and at least one of them improved. symptoms. This rate was 66.7 n  10 in the AW group. Both groups showed similar clinical improvement with VPS  p  0.1169. Conclusions: The placement of ventriculoperitoenal shunt is widely used in the treatment of iNPH. As iNPH and AW has clinical similarities despite the discrepancies between underlying pathophysiological mechanisms and both clinical entities respond similarly to shunt treatment we advocate VPS surgery in the management of AW as well.

 Objectives: Aquaductal web AW is a special form of aqueductal stenosis with similar clinical presentation with idiopathic normal pressure hydrocephalus iNPH. iNPH is indeed a communicating hydrocephalus syndrome whereas AW is a noncommunicating subtype. Here, we aimed to investigate the similarities and differences between these two different chronic hydrocephalus syndromes in terms of clinical signs and symptoms, response to shunt treatment and postoperative complications. Methods: Forty-one patients who underwent shunt operation with the diagnosis of iNPH or AW at our clinic between January 2010-May 2019 were retrospectively analyzed. Patients were evaluated by age, gender, clinical sign and symptoms, comorbidities, intraoperative and postoperative complications, and early and late postoperative outpatient follow-up findings. Results: Twenty-six patients were classified as iNPH group and 15 patients as AW group. Patients in the AW group were significantly younger 45.5  15.6 years vs. 60.3  15.4 years than the iNPH group  p  0.006. There was no statistical difference between the groups in terms of subdural effusion formation, need for shunt revision  p  1.000. Chronic hydrocephalus symptoms regressed in 23 88.5 patients in the NPH group, and at least one of them improved. symptoms. This rate was 66.7 n  10 in the AW group. Both groups showed similar clinical improvement with VPS  p  0.1169. Conclusions: The placement of ventriculoperitoenal shunt is widely used in the treatment of iNPH. As iNPH and AW has clinical similarities despite the discrepancies between underlying pathophysiological mechanisms and both clinical entities respond similarly to shunt treatment we advocate VPS surgery in the management of AW as well.

Makale detayları

Comparative retrospective analysis of patients with idiopathic normal pressure hydrocephalus and aqueductal web-related aqueductal stenosis.

Yazarlar:

Alper Türkkan | Pınar Eser Ocak | Oğuz Altunyuva | Buket Sönmez | Rifat Özpar | Ahmet Bekar

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Brain and Nerve Surgery (Neurosurgery)

Dergi:

The European Research Journal Vol.9 Issue 6, pp.1464-1473

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001294107

pISSN:

2149-3189

Normal pressure hydrocephalus

aqueductal stenosis

ventriculoperitoneal (VP) shunt.

Sayı

Makale detayları

Comparative retrospective analysis of patients with idiopathic normal pressure hydrocephalus and aqueductal web-related aqueductal stenosis.

Yazarlar: Alper Türkkan | Pınar Eser Ocak | Oğuz Altunyuva | Buket Sönmez | Rifat Özpar | Ahmet Bekar

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Brain and Nerve Surgery (Neurosurgery)

Dergi: The European Research Journal Vol.9 Issue 6, pp.1464-1473

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001294107

pISSN: 2149-3189

Normal pressure hydrocephalus

aqueductal stenosis

ventriculoperitoneal (VP) shunt.

Sayı

Yazarlar:

Alper Türkkan | Pınar Eser Ocak | Oğuz Altunyuva | Buket Sönmez | Rifat Özpar | Ahmet Bekar

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Brain and Nerve Surgery (Neurosurgery)

Dergi:

The European Research Journal Vol.9 Issue 6, pp.1464-1473

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001294107

pISSN:

2149-3189