Investigation of Some Pesticides’ Effects on Activities of Glutathione Reductase and Glutathione S-Transferase Purified from Turkey Liver under in Vitro Conditions

Pınar GÜLLER; Ebru AKKEMİK; Sevil KÖR; Mehmet ÇİFTÇİ

doi:https://doi.org/10.21597/jist.458632

Makale detayları

Investigation of Some Pesticides’ Effects on Activities of Glutathione Reductase and Glutathione S-Transferase Purified from Turkey Liver under in Vitro Conditions

Yazarlar:

Pınar GÜLLER | Ebru AKKEMİK | Sevil KÖR | Mehmet ÇİFTÇİ

Yayıncı:

Igdir University

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Journal of the Institute of Science and Technology 2018 Vol.8 Issue 3, pp.211-217

Belge Tipi:

Makale

Yayın Tarihi:

9/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000465785

Sıklık:

Üç Aylık

eISSN:

2536-4618

DOI:

https://doi.org/10.21597/jist.458632

Özet:

 


Whereas a very small amount of pesticides which are used for elimination of undesirable species

and for a more fertile agriculture reach the target organism, majority of pesticides reach to nontarget organisms. It is

foreseen by our team that the pesticides used for various purposes may negatively affect the glutathione mechanism

of the organisms. However, determination of effective dosage range is the objective of our study subjects. For this

reason, the in vitro effects of widely used pesticides (lambda-cyhalothrin, cypermethrin, chlorpyrifos, dichlorvos,

glyphosate isopropylamine) on the activities of glutathione reductase (GR) and glutathione S-transferase

(GST) which are two important enzymes of the glutathione system have been investigated in this study. It has

been determined that when lambda-cyhalothrin does not affect the GR enzyme purified from the turkey liver,

chlorpyrifos, glyphosate isopropylamine, dichlorvos and cypermethrin cause inhibition. When the effects of

pesticides on GST enzyme purified from turkey liver were investigated in in vitro conditions, it was determined

that all examined pesticides had inhibitory effects. In this context, the potential doses which can create a risk for

live life, of pesticides that are commonly used, have been identified.

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Makale detayları

Investigation of Some Pesticides’ Effects on Activities of Glutathione Reductase and Glutathione S-Transferase Purified from Turkey Liver under in Vitro Conditions

Yazarlar: Pınar GÜLLER | Ebru AKKEMİK | Sevil KÖR | Mehmet ÇİFTÇİ

Yayıncı: Igdir University

Ana Başlıklar: Kimya mühendisliği

Dergi: Journal of the Institute of Science and Technology 2018 Vol.8 Issue 3, pp.211-217

Belge Tipi: Makale

Yayın Tarihi: 9/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000465785

Sıklık: Üç Aylık

eISSN: 2536-4618

DOI: https://doi.org/10.21597/jist.458632

Sayı

Yazarlar:

Pınar GÜLLER | Ebru AKKEMİK | Sevil KÖR | Mehmet ÇİFTÇİ

Yayıncı:

Igdir University

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Journal of the Institute of Science and Technology 2018 Vol.8 Issue 3, pp.211-217

Belge Tipi:

Makale

Yayın Tarihi:

9/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000465785

Sıklık:

Üç Aylık

eISSN:

2536-4618

DOI:

https://doi.org/10.21597/jist.458632