Evaluation of pancreas elastography in pediatric patients diagnosed with Celiac disease

Didem Gülcü Taşkın; Okan Dılek

Makale detayları

Evaluation of pancreas elastography in pediatric patients diagnosed with Celiac disease

Yazarlar:

Didem Gülcü Taşkın | Okan Dılek

Yayıncı:

Cukurova University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Cukurova Medical Journal Vol.48 Issue 1, pp.227-233

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282234

pISSN:

2602-3032

Anahtar kelimeler:

Özet:

 Purpose: The goal of this study was to evaluate the pancreatic parenchyma in celiac patients with transabdominal ultrasonography US and ultrasound elastography UE. The aim of this study is to identify the difference of pancreatic elastography values and pancreatic dimension between the different four pediatric coeliac patient groups with respect to their development curve standart deviation SD scores. Materials and Methods: This study is single-center, prospective study. We included 518 years old patients diagnosed with Celiac Disease CD. Pancreatic dimension and parenchymal elastography measurements of 106 patients eligible for the study were performed by a single radiologist. Height, weight, body mass index BMI, fecal elastase values, age at diagnosis, duration of illness and medical history of the patients were evaluated. The patients were divided into four groups with respect to their development curve SD scores. Results: Our study group included 106 CD patients, 72 female and 34 male children were included in our study. The age at diagnosis of the patients was 100.497.5 months, and the disease duration was 4.12.5 years. The patients were examined in 4 groups. There was no difference in pancreatic elastography values between four groups. There was no difference in the dimensions of the pancreatic head between these groups. It was observed that the anteroposterior diameters of the body and tail increased as SD values increased. There was no difference between fecal elastase values. Conclusion: Pancreas dimensions were higher in celiac patients with a higher kilogram SD score. However, no significant difference in pancreatic elastography values was observed when the kilogram SD score was used.

 Purpose: The goal of this study was to evaluate the pancreatic parenchyma in celiac patients with transabdominal ultrasonography US and ultrasound elastography UE. The aim of this study is to identify the difference of pancreatic elastography values and pancreatic dimension between the different four pediatric coeliac patient groups with respect to their development curve standart deviation SD scores. Materials and Methods: This study is single-center, prospective study. We included 518 years old patients diagnosed with Celiac Disease CD. Pancreatic dimension and parenchymal elastography measurements of 106 patients eligible for the study were performed by a single radiologist. Height, weight, body mass index BMI, fecal elastase values, age at diagnosis, duration of illness and medical history of the patients were evaluated. The patients were divided into four groups with respect to their development curve SD scores. Results: Our study group included 106 CD patients, 72 female and 34 male children were included in our study. The age at diagnosis of the patients was 100.497.5 months, and the disease duration was 4.12.5 years. The patients were examined in 4 groups. There was no difference in pancreatic elastography values between four groups. There was no difference in the dimensions of the pancreatic head between these groups. It was observed that the anteroposterior diameters of the body and tail increased as SD values increased. There was no difference between fecal elastase values. Conclusion: Pancreas dimensions were higher in celiac patients with a higher kilogram SD score. However, no significant difference in pancreatic elastography values was observed when the kilogram SD score was used.

 Purpose: The goal of this study was to evaluate the pancreatic parenchyma in celiac patients with transabdominal ultrasonography US and ultrasound elastography UE. The aim of this study is to identify the difference of pancreatic elastography values and pancreatic dimension between the different four pediatric coeliac patient groups with respect to their development curve standart deviation SD scores. Materials and Methods: This study is single-center, prospective study. We included 518 years old patients diagnosed with Celiac Disease CD. Pancreatic dimension and parenchymal elastography measurements of 106 patients eligible for the study were performed by a single radiologist. Height, weight, body mass index BMI, fecal elastase values, age at diagnosis, duration of illness and medical history of the patients were evaluated. The patients were divided into four groups with respect to their development curve SD scores. Results: Our study group included 106 CD patients, 72 female and 34 male children were included in our study. The age at diagnosis of the patients was 100.497.5 months, and the disease duration was 4.12.5 years. The patients were examined in 4 groups. There was no difference in pancreatic elastography values between four groups. There was no difference in the dimensions of the pancreatic head between these groups. It was observed that the anteroposterior diameters of the body and tail increased as SD values increased. There was no difference between fecal elastase values. Conclusion: Pancreas dimensions were higher in celiac patients with a higher kilogram SD score. However, no significant difference in pancreatic elastography values was observed when the kilogram SD score was used.

 Amaç: Çalışmamızda Çölyak Hastalarında ÇH pankreas parankimi transabdominal ultrasonografi USG ve elastografi ile değerlendirildi. Çalışmada ÇHlerde pankreas elastografi ve pankreas boyutunun ölçümü ile hastaların gelişim eğrilerinin karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: Çalışmamız tek merkezli, prospektif tasarlanmış olup Çölyak Hastalığı tanılı, 5-18 yaş arası hastalar dahil edilmiştir. Çalışmaya uygun olan 106 hastanın pankreas boyutları ve parankim elastografi ölçümleri tek radyolog tarafından yapıldı. Hastaların boy, kilo, vücut kitle indeksi VKİ, fekal elastaz değerleri, tanı yaşları, hastalık süreleri ve özgeçmişleri değerlendirildi. Hastalar gelişim eğrileri standart deviasyon SD skoruna göre dört gruba ayrıldı. Bulgular: Çalışmamıza 106 ÇH dahil edilmiş olup bunların 72si kız, 34ü erkek idi. Hastaların tanı yaşları ortalama 100,497,5 ay, tanı süreleri ise 4,12,5 yıl olarak hesaplandı. Hastalar gelişim eğrilerinin SD skorlarına göre -2SD, -1, -2SD, -1,0SD, 0 SD grupları 4 grupta incelendi. Gruplar arasında pankreas elastografi değerleri arasında anlamlı farklılık saptanmadı. Yine bu gruplar arasında pankreas baş kısmı boyutlarında farklılık saptanmadı. Gözlemlendiği kadarıyla gövde ve kuyruk kısmı ön-arka çapları ile SD skoru arttıkça pozitif korelasyon izlendi sırası ile pankreas gövde; 9,751,4, 8,91,5, 10,21,8, 10,71,9 mm, pankreas kuyruk; 7,750,9, 7,21,4, 8,141,4, 8,41,4 mm. Fekal elastaz değerleri arasında da bir fark saptanmadı. Sonuç: Çölyak hastalarında kilogram SD skoruna göre yapılan değerlendirmede SD skoru yüksek olan hastaların pankreas boyutlarının daha büyük olduğu saptandı. Ancak kilogram SD skoruna göre pankreas elastografi değerleri arasında anlamlı bir faklılık saptanmadı.

Makale detayları

Evaluation of pancreas elastography in pediatric patients diagnosed with Celiac disease

Yazarlar:

Didem Gülcü Taşkın | Okan Dılek

Yayıncı:

Cukurova University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Cukurova Medical Journal Vol.48 Issue 1, pp.227-233

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282234

pISSN:

2602-3032

celiac disease

child

pancreas

elastography

fecal elastases

çocuk

pankreas

elastografi

fekal elastaz

Çölyak hastalığı

Sayı

Makale detayları

Yazarlar: Didem Gülcü Taşkın | Okan Dılek

Yayıncı: Cukurova University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Cukurova Medical Journal Vol.48 Issue 1, pp.227-233

Belge Tipi: Makale

Yayın Tarihi: 3/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001282234

pISSN: 2602-3032

Sayı

Yazarlar:

Didem Gülcü Taşkın | Okan Dılek

Yayıncı:

Cukurova University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Cukurova Medical Journal Vol.48 Issue 1, pp.227-233

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282234

pISSN:

2602-3032