COMPARISON OF THE EFFICACY AND SAFETY OF ISEPAMICIN AND AMIKACIN IN THE TREATMENT OF URINARY TRACT INFECTION IN CHILDREN

Arif BAHAR; Ferhan KARADEMİR; Tolga UNSUR; Mustafa ÖZYURT; İsmail GÖÇMEN

Makale detayları

COMPARISON OF THE EFFICACY AND SAFETY OF ISEPAMICIN AND AMIKACIN IN THE TREATMENT OF URINARY TRACT INFECTION IN CHILDREN

Yazarlar:

Arif BAHAR | Ferhan KARADEMİR | Tolga UNSUR | Mustafa ÖZYURT | İsmail GÖÇMEN

Yayıncı:

Marmara University

Ana Başlıklar:

Hastalıklar

Dergi:

Marmara Medical Journal 2003 Vol.16 Issue 2, pp.107-112

Belge Tipi:

Makale

Yayın Tarihi:

12/2016

Belge Dili:

İngilizce

Document ID (Org No.):

2000546228

Sıklık:

Aylık

eISSN:

1309-9469

pISSN:

1019-1941

Özet:

 


Objective: In this study we aimed to compare the efficacy and safety of isepamicin versus amikacin at a dose of 7.5 mg/kg of body weight twice daily for 10-14 days in children with urinary tract infections (UTI).Methods: One hundred and seventeen patients with urinary tract infection were enrolled in this study. Patients were randomized to treatment with isepamicin or amikacin in a 1:2 ratio. Urinary tract infections were treated with isepamicin (n=42), or amikacin (n=75).Results: The most commonly isolatedpathogens were Escherichia coli, Staphylococcus spp., Klebsiella pneumonia, Proteus mirabilis and Enterobacter spp. The overall clinical response rate at the end of treatment was excellent in all treatment groups (93.0/93.4% cured) with no significant differences between isepamicin and amikacin in patients with infections. None of the patients had a life-threatening or severe adverse event that required discontinuation of the drug.Conclusion: Isepamicin was shown to be as effective and as well tolerated as amikacin in the treatment of urinary tract infections in pediatric patients.

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Makale detayları

COMPARISON OF THE EFFICACY AND SAFETY OF ISEPAMICIN AND AMIKACIN IN THE TREATMENT OF URINARY TRACT INFECTION IN CHILDREN

Yazarlar: Arif BAHAR | Ferhan KARADEMİR | Tolga UNSUR | Mustafa ÖZYURT | İsmail GÖÇMEN

Yayıncı: Marmara University

Ana Başlıklar: Hastalıklar

Dergi: Marmara Medical Journal 2003 Vol.16 Issue 2, pp.107-112

Belge Tipi: Makale

Yayın Tarihi: 12/2016

Belge Dili: İngilizce

Document ID (Org No.): 2000546228

Sıklık: Aylık

eISSN: 1309-9469

pISSN: 1019-1941

Sayı

Yazarlar:

Arif BAHAR | Ferhan KARADEMİR | Tolga UNSUR | Mustafa ÖZYURT | İsmail GÖÇMEN

Yayıncı:

Marmara University

Ana Başlıklar:

Hastalıklar

Dergi:

Marmara Medical Journal 2003 Vol.16 Issue 2, pp.107-112

Belge Tipi:

Makale

Yayın Tarihi:

12/2016

Belge Dili:

İngilizce

Document ID (Org No.):

2000546228

Sıklık:

Aylık

eISSN:

1309-9469

pISSN:

1019-1941