COMPARATIVE ASSESSMENT OF AUDITORY AND VESTIBULAR FUNCTIONS IN MULTIPLE SCLEROSIS PATIENTS USING AUDIOLOGICAL DIAGNOSTIC TOOLS

Serap Uçar; Özgür Sürmelioğlu; Halime Dana

Makale detayları

COMPARATIVE ASSESSMENT OF AUDITORY AND VESTIBULAR FUNCTIONS IN MULTIPLE SCLEROSIS PATIENTS USING AUDIOLOGICAL DIAGNOSTIC TOOLS

Yazarlar:

Serap Uçar | Özgür Sürmelioğlu | Halime Dana

Yayıncı:

Aydin Adnan Menderes University

Ana Başlıklar:

Otorhinolaryngology | Cellular Nervous System | Allied Health and Rehabilitation Science (Other)

Dergi:

Meandros Medical And Dental Journal Vol.25 Issue 4, pp.412-423

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001334513

pISSN:

2149-9063

Anahtar kelimeler:

Özet:

 Objective: Multiple sclerosis, a demyelinating disease of the central nervous system, is characterized by weakness of the arms and legs, sensory symptoms, ataxia, fatigue, diplopia, memory, concentration, attention disorder, and motor speech disorder. Common symptoms include epileptic seizures, cognitive impairment, hearing loss, and cortical symptoms. Materials and Methods: This study evaluated patients mental functions with multiple sclerosis MS by considering their auditory and vestibular functions. A total of 30 patients, 15 healthy and 15 diseased, were recruited. In contrast, the experimental group consisted of individuals diagnosed with MS who had not had an attack for the last two months, over the age of 18, under the age of 60, and with similar characteristics in terms of gender. The audiological and vestibular tests on the experimental and patient groups were applied and the data obtained from these two groups were compared. Impedance audiometry test was performed on patients simultaneously. Result: The data obtained from our study, significant results were obtained for the right and left ears of MS patients to whom we applied the pure tone audiometry test. In the ABR test, unilateral hearing loss was observed in seven patients. In the VHIT test, while the VOR gains of 9 MS patients were outside the normal limits, the VOR gains of one patient in the left lateral canal were low. In the VEMP test, the wave latencies of 12 patients in the patient group were delayed, and the two patients left-side P1 and N1 waveforms were not observed.

 Objective: Multiple sclerosis, a demyelinating disease of the central nervous system, is characterized by weakness of the arms and legs, sensory symptoms, ataxia, fatigue, diplopia, memory, concentration, attention disorder, and motor speech disorder. Common symptoms include epileptic seizures, cognitive impairment, hearing loss, and cortical symptoms. Materials and Methods: This study evaluated patients mental functions with multiple sclerosis MS by considering their auditory and vestibular functions. A total of 30 patients, 15 healthy and 15 diseased, were recruited. In contrast, the experimental group consisted of individuals diagnosed with MS who had not had an attack for the last two months, over the age of 18, under the age of 60, and with similar characteristics in terms of gender. The audiological and vestibular tests on the experimental and patient groups were applied and the data obtained from these two groups were compared. Impedance audiometry test was performed on patients simultaneously. Result: The data obtained from our study, significant results were obtained for the right and left ears of MS patients to whom we applied the pure tone audiometry test. In the ABR test, unilateral hearing loss was observed in seven patients. In the VHIT test, while the VOR gains of 9 MS patients were outside the normal limits, the VOR gains of one patient in the left lateral canal were low. In the VEMP test, the wave latencies of 12 patients in the patient group were delayed, and the two patients left-side P1 and N1 waveforms were not observed.

 Objective: Multiple sclerosis, a demyelinating disease of the central nervous system, is characterized by weakness of the arms and legs, sensory symptoms, ataxia, fatigue, diplopia, memory, concentration, attention disorder, and motor speech disorder. Common symptoms include epileptic seizures, cognitive impairment, hearing loss, and cortical symptoms. Materials and Methods: This study evaluated patients mental functions with multiple sclerosis MS by considering their auditory and vestibular functions. A total of 30 patients, 15 healthy and 15 diseased, were recruited. In contrast, the experimental group consisted of individuals diagnosed with MS who had not had an attack for the last two months, over the age of 18, under the age of 60, and with similar characteristics in terms of gender. The audiological and vestibular tests on the experimental and patient groups were applied and the data obtained from these two groups were compared. Impedance audiometry test was performed on patients simultaneously. Result: The data obtained from our study, significant results were obtained for the right and left ears of MS patients to whom we applied the pure tone audiometry test. In the ABR test, unilateral hearing loss was observed in seven patients. In the VHIT test, while the VOR gains of 9 MS patients were outside the normal limits, the VOR gains of one patient in the left lateral canal were low. In the VEMP test, the wave latencies of 12 patients in the patient group were delayed, and the two patients left-side P1 and N1 waveforms were not observed.

 Amaç: Multipl skleroz MS, Merkezi sinir sisteminin demiyelinizan bir hastalığı olarak, kol ve bacaklarda güçsüzlük, duyusal semptomlar, ataksi, yorgunluk, diplopi, hafıza, konsantrasyon, dikkat bozukluğu ve motor konuşma bozukluğu ile karakterize edilir. Yaygın semptomlar arasında epileptik nöbetler, bilişsel bozukluk, işitme kaybı ve kortikal semptomlar bulunur. Bu çalışmanın amacı MSin işitsel ve vestibüler yollar üzerindeki etkisini belirlemektir. Gereç ve Yöntemler: Bu çalışmada multipl sklerozlu hastaların işitsel ve vestibüler fonksiyonları göz önünde bulundurularak zihinsel fonksiyonları değerlendirildi. 15 sağlıklı kontrol ve 15 MS hastası olmak üzere toplam 30 hasta çalışmaya alındı. Deney grubu ise son iki aylık dönemde atak geçirmemiş, 18 ile 60 yaş aralığında ve benzer cinsiyet özelliklere sahip MS tanısı almış bireylerden oluşturuldu. Deney ve hasta gruplarına odyolojik ve vestibüler testler uygulandı ve bu iki gruptan elde edilen veriler karşılaştırıldı. Hastalara eş zamanlı olarak empedans odyometri testi uygulandı. Bulgular: Çalışmamızdan elde edilen verilerde, saf ses odyometrisi testini uyguladığımız MS hastalarının sağ ve sol kulakları için anlamlı sonuçlar elde edildi. İşitsel beyin sapı cevabı ABR testinde yedi hastada tek taraflı sensörinöral işitme kaybı gözlendi. Video Baş Savurma Testinde VHIT 9 MS hastasının Vestibülo-oküler reflex VOR kazanımları normal sınırların dışında iken, bir hastanın sol lateral kanaldaki VOR kazanımları düşüktü. Vestibüler uyarılmış miyojenik potansiyeller VEMP testinde hasta grubunda 12 hastanın dalga latansları gecikti ve iki hastanın sol taraf P1 ve N1 dalga formları gözlenmedi. Sonuç: Çalışmamızın bulgularına dayanarak, MS hastalarında işitsel ve vestibüler fonksiyonların önemli ölçüde bozulduğunu söyleyebiliriz. Daha geniş hasta popülasyonları ile çalışmaların geliştirilmesini önerebiliriz.

Makale detayları

COMPARATIVE ASSESSMENT OF AUDITORY AND VESTIBULAR FUNCTIONS IN MULTIPLE SCLEROSIS PATIENTS USING AUDIOLOGICAL DIAGNOSTIC TOOLS

Yazarlar:

Serap Uçar | Özgür Sürmelioğlu | Halime Dana

Yayıncı:

Aydin Adnan Menderes University

Ana Başlıklar:

Otorhinolaryngology | Cellular Nervous System | Allied Health and Rehabilitation Science (Other)

Dergi:

Meandros Medical And Dental Journal Vol.25 Issue 4, pp.412-423

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001334513

pISSN:

2149-9063

MS

pure tone audiometry

ABR

vestibular function tests

psychosocial problemsABR

MS

psikososyal sorunlar

vestibüler fonksiyon testleri

saf ses odyometrisi

Sayı

Makale detayları

Yazarlar: Serap Uçar | Özgür Sürmelioğlu | Halime Dana

Yayıncı: Aydin Adnan Menderes University

Ana Başlıklar: Otorhinolaryngology | Cellular Nervous System | Allied Health and Rehabilitation Science (Other)

Dergi: Meandros Medical And Dental Journal Vol.25 Issue 4, pp.412-423

Belge Tipi: Makale

Yayın Tarihi: 12/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001334513

pISSN: 2149-9063

Sayı

Yazarlar:

Serap Uçar | Özgür Sürmelioğlu | Halime Dana

Yayıncı:

Aydin Adnan Menderes University

Ana Başlıklar:

Otorhinolaryngology | Cellular Nervous System | Allied Health and Rehabilitation Science (Other)

Dergi:

Meandros Medical And Dental Journal Vol.25 Issue 4, pp.412-423

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001334513

pISSN:

2149-9063