Outcomes of Intravenous Thrombolytic Therapy in Acute Ischemic Stroke

Aysu Yetiş; Burc Esra Sahin; Aydan Köysüren; Selcen Duran; Asuman Çelikbilek

Makale detayları

Outcomes of Intravenous Thrombolytic Therapy in Acute Ischemic Stroke

Yazarlar:

Aysu Yetiş | Burc Esra Sahin | Aydan Köysüren | Selcen Duran | Asuman Çelikbilek

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Ahi Evran Tıp Dergisi Vol.8 Issue 2, pp.151-156

Belge Tipi:

Makale

Yayın Tarihi:

8/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001324054

pISSN:

2619-9203

Anahtar kelimeler:

Özet:

 Purpose: In this study, we aimed to share our experiences about the efficacy, complications and prognosis of intravenous recombinant tissue plasminogen activator iv rt-PA in patients with acute ischaemic stroke in our stroke unit. Materials and Methods: Between September 2018 and December 2021, 39 patients who underwent iv rt-PA in our stroke unit were retrospectively analysed. Demographic characteristics, stroke risk factors, symptom-door, symptom-needle time, NIHSS National Institutes of Health Stroke Scale and MRS Modified Rankin Scale values of the patients were recorded from their files. Results: Twenty-two patients were female 56.4 and 17 were male 43.6. The most common risk factors were hypertension 56.4 and hyperlipidemia 46.2. NIHSS scores at admission, 24 h and day 7 were 17.35.9, 13.48.7, 11.110.3, respectively. Cerebral haemorrhage was detected in only 9 23.1 of the patients and death was detected in 12 30.8. Conclusion: Iv rt-PA treatment is an effective and safe method for acute ischemic stroke. Increasing public awareness and the number of stroke units and centers in stroke treatment will significantly improve success rates to much higher levels.

 Purpose: In this study, we aimed to share our experiences about the efficacy, complications and prognosis of intravenous recombinant tissue plasminogen activator iv rt-PA in patients with acute ischaemic stroke in our stroke unit. Materials and Methods: Between September 2018 and December 2021, 39 patients who underwent iv rt-PA in our stroke unit were retrospectively analysed. Demographic characteristics, stroke risk factors, symptom-door, symptom-needle time, NIHSS National Institutes of Health Stroke Scale and MRS Modified Rankin Scale values of the patients were recorded from their files. Results: Twenty-two patients were female 56.4 and 17 were male 43.6. The most common risk factors were hypertension 56.4 and hyperlipidemia 46.2. NIHSS scores at admission, 24 h and day 7 were 17.35.9, 13.48.7, 11.110.3, respectively. Cerebral haemorrhage was detected in only 9 23.1 of the patients and death was detected in 12 30.8. Conclusion: Iv rt-PA treatment is an effective and safe method for acute ischemic stroke. Increasing public awareness and the number of stroke units and centers in stroke treatment will significantly improve success rates to much higher levels.

 Purpose: In this study, we aimed to share our experiences about the efficacy, complications and prognosis of intravenous recombinant tissue plasminogen activator iv rt-PA in patients with acute ischaemic stroke in our stroke unit. Materials and Methods: Between September 2018 and December 2021, 39 patients who underwent iv rt-PA in our stroke unit were retrospectively analysed. Demographic characteristics, stroke risk factors, symptom-door, symptom-needle time, NIHSS National Institutes of Health Stroke Scale and MRS Modified Rankin Scale values of the patients were recorded from their files. Results: Twenty-two patients were female 56.4 and 17 were male 43.6. The most common risk factors were hypertension 56.4 and hyperlipidemia 46.2. NIHSS scores at admission, 24 h and day 7 were 17.35.9, 13.48.7, 11.110.3, respectively. Cerebral haemorrhage was detected in only 9 23.1 of the patients and death was detected in 12 30.8. Conclusion: Iv rt-PA treatment is an effective and safe method for acute ischemic stroke. Increasing public awareness and the number of stroke units and centers in stroke treatment will significantly improve success rates to much higher levels.

 Amaç: Bu çalışmada inme ünitemizde intravenöz rekombinan doku plazminojen aktivatörü iv rt-PA uyguladığımız akut iskemik inme tanılı hastaların verilerini inceleyerek tedavinin etkinliği, komplikasyonları ve prognozları hakkında deneyimlerimizi paylaşmayı amaçladık. Araçlar ve Yöntem: Eylül 2018 ve Aralık 2021 yılları arasında inme ünitemizde iv rt-PA uyguladığımız 39 hasta retrospektif olarak incelendi. Hastaların demografik özellikleri, inme risk faktörleri, semptom-kapı, semptom-iğne zamanı, NIHSS National Institutes of Health Stroke Scale ve MRS Modified Rankin Scale değerleri dosyalarından kaydedildi. Bulgular: Hastaların 22sikadın  56.4,17si erkekti 43.6. En sık görülen risk faktörü hipertansiyon 56.4 ve hiperlipidemiydi 46.2. Hastaların giriş, 24. saat ve 7. gününde bakılan NIHSS skorları sırasıyla 17.35.9, 13.48.7, 11.110.3idi. Hastaların sadece 9unda 23.1 serebral kanama saptanırken, 12sinde 30.8 ölüm olduğu saptandı. Sonuç: Ivrt-PA tedavisi akut iskemik inmede etkili ve güvenli bir yöntemdir. İnme tedavisinde toplumsal farkındalığın artırılması, inme ünitesi ve merkezlerinin sayılarının artırılması ile başarı oranları çok daha iyi seviyelere yükselecektir.

Makale detayları

Outcomes of Intravenous Thrombolytic Therapy in Acute Ischemic Stroke

Yazarlar:

Aysu Yetiş | Burc Esra Sahin | Aydan Köysüren | Selcen Duran | Asuman Çelikbilek

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Ahi Evran Tıp Dergisi Vol.8 Issue 2, pp.151-156

Belge Tipi:

Makale

Yayın Tarihi:

8/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001324054

pISSN:

2619-9203

retrospective

patient

treatment successhasta

retrospektif

tedavi başarısı

Sayı

Makale detayları

Outcomes of Intravenous Thrombolytic Therapy in Acute Ischemic Stroke

Yazarlar: Aysu Yetiş | Burc Esra Sahin | Aydan Köysüren | Selcen Duran | Asuman Çelikbilek

Yayıncı: Kirsehir Ahi Evran University

Ana Başlıklar: Klinik Tıp Bilimleri (Diğer)

Dergi: Ahi Evran Tıp Dergisi Vol.8 Issue 2, pp.151-156

Belge Tipi: Makale

Yayın Tarihi: 8/2024

Belge Dili: Türkçe

Document ID (Org No.): 2001324054

pISSN: 2619-9203

retrospective

patient

treatment successhasta

retrospektif

tedavi başarısı

Sayı

Yazarlar:

Aysu Yetiş | Burc Esra Sahin | Aydan Köysüren | Selcen Duran | Asuman Çelikbilek

Yayıncı:

Kirsehir Ahi Evran University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Ahi Evran Tıp Dergisi Vol.8 Issue 2, pp.151-156

Belge Tipi:

Makale

Yayın Tarihi:

8/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001324054

pISSN:

2619-9203