Utility of preoperative neutrophil–lymphocyte and platelet–lymphocyte ratios in differential diagnosis of benign, borderline, and malignant ovarian tumors

Sahra Sultan Kara; Esra Keles; Derya Sivri Aydın; Emre Mat; Gazi Yıldız; Rezzan Berna Temoçin; Pınar Birol; Pınar Yıldız

Makale detayları

Utility of preoperative neutrophil–lymphocyte and platelet–lymphocyte ratios in differential diagnosis of benign, borderline, and malignant ovarian tumors

Yazarlar:

Sahra Sultan Kara | Esra Keles | Derya Sivri Aydın | Emre Mat | Gazi Yıldız | Rezzan Berna Temoçin | Pınar Birol | Pınar Yıldız

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Health Care Administration

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.40 Issue 2, pp.333-336

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293714

pISSN:

1309-4483

Anahtar kelimeler:

Özet:

 To investigate the utility of preoperative neutrophillymphocyte ratio NLR and plateletlymphocyte ratio PLR in the differential diagnosis of benign, borderline, and malignant ovarian tumors. This retrospective study was conducted on patients with adnexal masses who underwent surgical resection at Haseki Training and Research Hospital between September 2008 and September 2015. Sociodemographic characteristics, histopathological results and laboratory parameters were obtained from medical reports. Hematological parameters and calculated NLR and PLR were analyzed between tumor groups using IBM SPSS statistics version 22. 381 patients with a mean age of 40.81 age range: 13-83 years were included. Of those, 293 patients 76.91 had benign ovarian tumors, 18 4.72 had borderline, and 70 18.37 had malignant ovarian tumors. The mean NLR was 2.318  2.29 and the mean PLR was 134.35  59 in benign ovarian tumors, the mean NLR was 4.275.23 and the mean PLR was 165.0698.72 in borderline ovarian tumors, the mean NLR was 4.084.37 and the mean PLR was 194.72114.85 in malign ovarian tumors. The NLR and PLR were significantly higher in malignant than benign or borderline ovarian tumors all p 0.0001. The diagnostic cut-off value of NLR for differentiating between benign or borderline and malignant tumors was 1.17, whereas that of PLR for distinguishing between benignborderline and malignancy was 87.94.The present study indicated that NLR and PLR were significantly higher in ovarian cancers than in benign or borderline ovarian masses. Preoperative NLR and PLR values may help distinguish malignant from benign or borderline ovarian tumors.

 To investigate the utility of preoperative neutrophillymphocyte ratio NLR and plateletlymphocyte ratio PLR in the differential diagnosis of benign, borderline, and malignant ovarian tumors. This retrospective study was conducted on patients with adnexal masses who underwent surgical resection at Haseki Training and Research Hospital between September 2008 and September 2015. Sociodemographic characteristics, histopathological results and laboratory parameters were obtained from medical reports. Hematological parameters and calculated NLR and PLR were analyzed between tumor groups using IBM SPSS statistics version 22. 381 patients with a mean age of 40.81 age range: 13-83 years were included. Of those, 293 patients 76.91 had benign ovarian tumors, 18 4.72 had borderline, and 70 18.37 had malignant ovarian tumors. The mean NLR was 2.318  2.29 and the mean PLR was 134.35  59 in benign ovarian tumors, the mean NLR was 4.275.23 and the mean PLR was 165.0698.72 in borderline ovarian tumors, the mean NLR was 4.084.37 and the mean PLR was 194.72114.85 in malign ovarian tumors. The NLR and PLR were significantly higher in malignant than benign or borderline ovarian tumors all p 0.0001. The diagnostic cut-off value of NLR for differentiating between benign or borderline and malignant tumors was 1.17, whereas that of PLR for distinguishing between benignborderline and malignancy was 87.94.The present study indicated that NLR and PLR were significantly higher in ovarian cancers than in benign or borderline ovarian masses. Preoperative NLR and PLR values may help distinguish malignant from benign or borderline ovarian tumors.

 To investigate the utility of preoperative neutrophillymphocyte ratio NLR and plateletlymphocyte ratio PLR in the differential diagnosis of benign, borderline, and malignant ovarian tumors. This retrospective study was conducted on patients with adnexal masses who underwent surgical resection at Haseki Training and Research Hospital between September 2008 and September 2015. Sociodemographic characteristics, histopathological results and laboratory parameters were obtained from medical reports. Hematological parameters and calculated NLR and PLR were analyzed between tumor groups using IBM SPSS statistics version 22. 381 patients with a mean age of 40.81 age range: 13-83 years were included. Of those, 293 patients 76.91 had benign ovarian tumors, 18 4.72 had borderline, and 70 18.37 had malignant ovarian tumors. The mean NLR was 2.318  2.29 and the mean PLR was 134.35  59 in benign ovarian tumors, the mean NLR was 4.275.23 and the mean PLR was 165.0698.72 in borderline ovarian tumors, the mean NLR was 4.084.37 and the mean PLR was 194.72114.85 in malign ovarian tumors. The NLR and PLR were significantly higher in malignant than benign or borderline ovarian tumors all p 0.0001. The diagnostic cut-off value of NLR for differentiating between benign or borderline and malignant tumors was 1.17, whereas that of PLR for distinguishing between benignborderline and malignancy was 87.94.The present study indicated that NLR and PLR were significantly higher in ovarian cancers than in benign or borderline ovarian masses. Preoperative NLR and PLR values may help distinguish malignant from benign or borderline ovarian tumors.

 To investigate the utility of preoperative neutrophillymphocyte ratio NLR and plateletlymphocyte ratio PLR in the differential diagnosis of benign, borderline, and malignant ovarian tumors. This retrospective study was conducted on patients with adnexal masses who underwent surgical resection at Haseki Training and Research Hospital between September 2008 and September 2015. Sociodemographic characteristics, histopathological results and laboratory parameters were obtained from medical reports. Hematological parameters and calculated NLR and PLR were analyzed between tumor groups using IBM SPSS statistics version 22. 381 patients with a mean age of 40.81 age range: 13-83 years were included. Of those, 293 patients 76.91 had benign ovarian tumors, 18 4.72 had borderline, and 70 18.37 had malignant ovarian tumors. The mean NLR was 2.318  2.29 and the mean PLR was 134.35  59 in benign ovarian tumors, the mean NLR was 4.275.23 and the mean PLR was 165.0698.72 in borderline ovarian tumors, the mean NLR was 4.084.37 and the mean PLR was 194.72114.85 in malign ovarian tumors. The NLR and PLR were significantly higher in malignant than benign or borderline ovarian tumors all p 0.0001. The diagnostic cut-off value of NLR for differentiating between benign or borderline and malignant tumors was 1.17, whereas that of PLR for distinguishing between benignborderline and malignancy was 87.94.The present study indicated that NLR and PLR were significantly higher in ovarian cancers than in benign or borderline ovarian masses. Preoperative NLR and PLR values may help distinguish malignant from benign or borderline ovarian tumors.

Makale detayları

Utility of preoperative neutrophil–lymphocyte and platelet–lymphocyte ratios in differential diagnosis of benign, borderline, and malignant ovarian tumors

Yazarlar:

Sahra Sultan Kara | Esra Keles | Derya Sivri Aydın | Emre Mat | Gazi Yıldız | Rezzan Berna Temoçin | Pınar Birol | Pınar Yıldız

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Health Care Administration

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.40 Issue 2, pp.333-336

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293714

pISSN:

1309-4483

ovary tumor

neutrophil/lymphocyte ratio (NLR)

platelet/lymphocyte ratio (PLR)ovary tumor

neutrophil/lymphocyte ratio (NLR)

platelet/lymphocyte ratio (PLR)

Sayı

Makale detayları

Utility of preoperative neutrophil–lymphocyte and platelet–lymphocyte ratios in differential diagnosis of benign, borderline, and malignant ovarian tumors

Yazarlar: Sahra Sultan Kara | Esra Keles | Derya Sivri Aydın | Emre Mat | Gazi Yıldız | Rezzan Berna Temoçin | Pınar Birol | Pınar Yıldız

Yayıncı: Ondokuz Mayıs University

Ana Başlıklar: Health Care Administration

Dergi: Deneysel ve Klinik Tıp Dergisi Vol.40 Issue 2, pp.333-336

Belge Tipi: Makale

Yayın Tarihi: 7/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001293714

pISSN: 1309-4483

ovary tumor

neutrophil/lymphocyte ratio (NLR)

platelet/lymphocyte ratio (PLR)ovary tumor

neutrophil/lymphocyte ratio (NLR)

platelet/lymphocyte ratio (PLR)

Sayı

Yazarlar:

Sahra Sultan Kara | Esra Keles | Derya Sivri Aydın | Emre Mat | Gazi Yıldız | Rezzan Berna Temoçin | Pınar Birol | Pınar Yıldız

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Health Care Administration

Dergi:

Deneysel ve Klinik Tıp Dergisi Vol.40 Issue 2, pp.333-336

Belge Tipi:

Makale

Yayın Tarihi:

7/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293714

pISSN:

1309-4483