Short Term Effects of Anti-VEGF Agents on Retinal Vascularity

Kemal Bayrakçeken

Makale detayları

Short Term Effects of Anti-VEGF Agents on Retinal Vascularity

Yazarlar:

Kemal Bayrakçeken

Yayıncı:

Gumushane University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi Vol.12 Issue 1, pp.187-191

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001285952

pISSN:

2146-9954

Anahtar kelimeler:

Özet:

 In this study, It is aimed to evaluate the early changes of the macula and retinal vascular tissues in patients who received antivascular endothelial growth factor VEGF injection for the treatment of macular edema secondary to retinal vascular diseases and age-related macular degeneration using optical coherence tomography OCT and optical coherence tomography angiography OCTA imaging. In our retrospective study, 30 eyes of 30 patients who were followed up in Erzincan Binali Yıldırım University Ophthalmology Clinic for retinal vascular disease between November 2021 and November 2022, were treated with anti-VEGF, and had OCT and OCTA imaging before and after the injection were included. Significant changes were detected in the OCT and OCTA findings before and after injection 10th minute, 1st day, and 1st week except for the foveal avascular zone p0.05. After the anti-VEGF treatment we applied in the treatment of macular edema due to retinal vascular diseases, it was observed that there was a decrease in macular thickness and vessel density in the acute period. Further studies with wider participation are needed.

 In this study, It is aimed to evaluate the early changes of the macula and retinal vascular tissues in patients who received antivascular endothelial growth factor VEGF injection for the treatment of macular edema secondary to retinal vascular diseases and age-related macular degeneration using optical coherence tomography OCT and optical coherence tomography angiography OCTA imaging. In our retrospective study, 30 eyes of 30 patients who were followed up in Erzincan Binali Yıldırım University Ophthalmology Clinic for retinal vascular disease between November 2021 and November 2022, were treated with anti-VEGF, and had OCT and OCTA imaging before and after the injection were included. Significant changes were detected in the OCT and OCTA findings before and after injection 10th minute, 1st day, and 1st week except for the foveal avascular zone p0.05. After the anti-VEGF treatment we applied in the treatment of macular edema due to retinal vascular diseases, it was observed that there was a decrease in macular thickness and vessel density in the acute period. Further studies with wider participation are needed.

 In this study, It is aimed to evaluate the early changes of the macula and retinal vascular tissues in patients who received antivascular endothelial growth factor VEGF injection for the treatment of macular edema secondary to retinal vascular diseases and age-related macular degeneration using optical coherence tomography OCT and optical coherence tomography angiography OCTA imaging. In our retrospective study, 30 eyes of 30 patients who were followed up in Erzincan Binali Yıldırım University Ophthalmology Clinic for retinal vascular disease between November 2021 and November 2022, were treated with anti-VEGF, and had OCT and OCTA imaging before and after the injection were included. Significant changes were detected in the OCT and OCTA findings before and after injection 10th minute, 1st day, and 1st week except for the foveal avascular zone p0.05. After the anti-VEGF treatment we applied in the treatment of macular edema due to retinal vascular diseases, it was observed that there was a decrease in macular thickness and vessel density in the acute period. Further studies with wider participation are needed.

 Bu çalışmada, retinal vasküler hastalıklara ve yaşa bağlı makula dejenerasyonuna ikincil gelişen maküla ödeminin tedavisi için anti-vasküler endotelyal büyüme faktörü VEGF enjeksiyonu uygulanan hastalarda akut dönemde optik koherens tomografi OCT ve optik koherens tomografi anjiyografi OCTA görüntülemeleri kullanılarak makülada ve retinal vasküler yapılardaki erken dönem değişikliklerin değerlendirilmesi amaçlanmıştır. Retrospektif çalışmamız için Erzincan Binali Yıldırım Üniversitesi Göz Hastalıkları Kliniğinde Kasım 2021 ile Kasım 2022 tarihleri arasında kliniğimizde retinal vasküler hastalık nedeniyle takip edilen, tedavilerinde anti-VEGF uyguladığımız, enjeksiyon öncesi ve sonrası erken dönemde OCT ve OCTA görüntülemeleri yapılan 30 hastanın 30 gözü dahil edilmiştir. Enjeksiyon öncesi ve sonrası 10.dakika,1.gün ve 1.hafta OCT ve OCTA bulgularında foveal avasküler zon dışında anlamlı değişiklik saptanmıştır p0,05. Retinal vaküler hastalıklara bağlı maküler ödem tedavisinde uyguladığımız anti-VEGF tedavisi sonrası akut dönemde maküla kalınlığında ve damar yoğunluğunda azalma olduğu görülmüştür. Daha geniş katılımlı çalışmalara ihtiyaç vardır.

Makale detayları

Short Term Effects of Anti-VEGF Agents on Retinal Vascularity

Yazarlar:

Kemal Bayrakçeken

Yayıncı:

Gumushane University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi Vol.12 Issue 1, pp.187-191

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001285952

pISSN:

2146-9954

Optical coherence tomography angiography

Retinal vacular diseases

Vascular endothelial growth factor.

Optik koherens tomografi anjiyografi

Retinal vaküler hastalıklar

Vasküler endotelyal büyüme faktörü.

Sayı

Makale detayları

Short Term Effects of Anti-VEGF Agents on Retinal Vascularity

Yazarlar: Kemal Bayrakçeken

Yayıncı: Gumushane University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi Vol.12 Issue 1, pp.187-191

Belge Tipi: Makale

Yayın Tarihi: 3/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001285952

pISSN: 2146-9954

Optical coherence tomography angiography

Retinal vacular diseases

Vascular endothelial growth factor.

Optik koherens tomografi anjiyografi

Retinal vaküler hastalıklar

Vasküler endotelyal büyüme faktörü.

Sayı

Yazarlar:

Kemal Bayrakçeken

Yayıncı:

Gumushane University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi Vol.12 Issue 1, pp.187-191

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001285952

pISSN:

2146-9954