Evaluation of Corneal Changes in Uveitic Patients by Non-Contact Specular Microscopy: A Retrospective Study

Abdullah Beyoğlu; Banu Turgut Öztürk; Ali Meşen; Yalçın Karaküçük

Makale detayları

Evaluation of Corneal Changes in Uveitic Patients by Non-Contact Specular Microscopy: A Retrospective Study

Yazarlar:

Abdullah Beyoğlu | Banu Turgut Öztürk | Ali Meşen | Yalçın Karaküçük

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.18 Issue 3, pp.7-12

Belge Tipi:

Makale

Yayın Tarihi:

11/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001303788

pISSN:

1303-6610

Anahtar kelimeler:

Özet:

 Objective: To demonstrate the changes in specular microscopy between uveitic eyes and healthy eyes. Material and Methods: A retrospective study included 66 patients followed in the Uvea clinic of Selcuk University between 2015-2018. The right eyes of all patients were evaluated. The right eye data of 37 healthy individuals were used as the control group. The patients were divided into subgroups anterior, intermediate, and posterior uveitis. Specular microscopy measurements were made with Confo Scan 4. Comparisons were made between the groups in terms of endothelial cell density ECD, pleomorphism , polymegatism , central corneal thickness CCT, and intraocular pressure IOP. A p-value less than 0.05 was considered significant. Results: The mean age was 33.7115.29 in the uveitis and 37.7813.17 in the control group p0.432. There was a significant difference between the groups in terms of ECD, pleomorphism and polymegatism all groups; p0.01. No significant difference was found in terms of CCT and IOP respectively; p0.812, p0.381. In the subgroup analysis, a significant difference was found between anterior, intermediate and posterior uveitis groups in terms of ECD respectively; p0.020, p0.018. However, no significant difference in other groups p0.999. In comparison with healthy eyes of patients with monocular uveitis were significant differences in all parameters all groups; p0.01. Conclusion: It is seen that ECD decreases, pleomorphism and polymegatism increase in patients with uveitis. This result showed the importance of preventing sequelae with early treatment in patients with uveitis. Speccular or confocal microscopy scanning is important in uveitic patients scheduled for intraocular surgery.

 Objective: To demonstrate the changes in specular microscopy between uveitic eyes and healthy eyes. Material and Methods: A retrospective study included 66 patients followed in the Uvea clinic of Selcuk University between 2015-2018. The right eyes of all patients were evaluated. The right eye data of 37 healthy individuals were used as the control group. The patients were divided into subgroups anterior, intermediate, and posterior uveitis. Specular microscopy measurements were made with Confo Scan 4. Comparisons were made between the groups in terms of endothelial cell density ECD, pleomorphism , polymegatism , central corneal thickness CCT, and intraocular pressure IOP. A p-value less than 0.05 was considered significant. Results: The mean age was 33.7115.29 in the uveitis and 37.7813.17 in the control group p0.432. There was a significant difference between the groups in terms of ECD, pleomorphism and polymegatism all groups; p0.01. No significant difference was found in terms of CCT and IOP respectively; p0.812, p0.381. In the subgroup analysis, a significant difference was found between anterior, intermediate and posterior uveitis groups in terms of ECD respectively; p0.020, p0.018. However, no significant difference in other groups p0.999. In comparison with healthy eyes of patients with monocular uveitis were significant differences in all parameters all groups; p0.01. Conclusion: It is seen that ECD decreases, pleomorphism and polymegatism increase in patients with uveitis. This result showed the importance of preventing sequelae with early treatment in patients with uveitis. Speccular or confocal microscopy scanning is important in uveitic patients scheduled for intraocular surgery.

 Objective: To demonstrate the changes in specular microscopy between uveitic eyes and healthy eyes. Material and Methods: A retrospective study included 66 patients followed in the Uvea clinic of Selcuk University between 2015-2018. The right eyes of all patients were evaluated. The right eye data of 37 healthy individuals were used as the control group. The patients were divided into subgroups anterior, intermediate, and posterior uveitis. Specular microscopy measurements were made with Confo Scan 4. Comparisons were made between the groups in terms of endothelial cell density ECD, pleomorphism , polymegatism , central corneal thickness CCT, and intraocular pressure IOP. A p-value less than 0.05 was considered significant. Results: The mean age was 33.7115.29 in the uveitis and 37.7813.17 in the control group p0.432. There was a significant difference between the groups in terms of ECD, pleomorphism and polymegatism all groups; p0.01. No significant difference was found in terms of CCT and IOP respectively; p0.812, p0.381. In the subgroup analysis, a significant difference was found between anterior, intermediate and posterior uveitis groups in terms of ECD respectively; p0.020, p0.018. However, no significant difference in other groups p0.999. In comparison with healthy eyes of patients with monocular uveitis were significant differences in all parameters all groups; p0.01. Conclusion: It is seen that ECD decreases, pleomorphism and polymegatism increase in patients with uveitis. This result showed the importance of preventing sequelae with early treatment in patients with uveitis. Speccular or confocal microscopy scanning is important in uveitic patients scheduled for intraocular surgery.

 Amaç: Üveitik gözler ile sağlıklı gözler arasında speküler mikrokopideki değişimlerin gösterilmesi. Gereç ve Yöntemler: Retrospektif çalışmaya 2015-2018 yıllarında Selçuk Üniversitesinde takip edilen 66 hasta alındı. Tüm hastaların sağ gözleri değerlendirildi. Kontrol grubu olarak normal göz muayene bulgularına sahip 37 bireyin sağ göz verileri kullanıldı. Hastalar, anterior, intermedyer ve posterior üveit olarak subgruplara ayrıldı. Speküler mikrokopi ölçümleri Confo Scan 4 ile yapıldı. Endotel hücre yoğunluğu EHY, pleomorfizm , polimegatizm , santral kornea kalınlığı SKK ve intraoküler basınç yönünden GİB gruplar karşılaştırıldı. İstatistiksel analizde p değerinin 0.05den küçük olması anlamlı kabul edildi. Bulgular: Yaş ortalaması üveitlerde 33.7115.29, kontrol grubunda ise 37.7813.17 olarak saptandı p0.432. EHY, pleomorfizm ve polimegatizm açısından gruplar arasında anlamlı fark tespit edildi tüm gruplar; p0.01. SKK ve GİB açısından ise anlamlı bir fark bulunamadı sırası ile; p0.812, p0.381. Alt grup analizinde EHY açısından ön üveit ile intermediyer ve posterior üveit grubu arasında anlamlı fark tespit edildi sırası ile; p0.020, p0.018. Ancak intermediyer üveiti olan grup ile posterior üveti olan grup arasında anlamlı bir farklılık tespit edilemedi p0.999. Monoküler üveiti olan hastaların sağlam gözleri ile karşılaştırmalarında ise tüm değişkenlerde fark vardı tüm gruplar; p0.01. Sonuç: Üveit hastalarında EHYnun azalmakta, pleomofizm ve polimegatizmin artmaktadır. Bu sonuç, üveit hastalarında erken tedavi ile sekel oluşumunun önüne geçilmesinin önemini gösterdi. İntraoküler cerrahi planlanan üveitik hastalarda speküler veya konfokal mikroskopi taraması önem arz etmektedir.

Makale detayları

Evaluation of Corneal Changes in Uveitic Patients by Non-Contact Specular Microscopy: A Retrospective Study

Yazarlar:

Abdullah Beyoğlu | Banu Turgut Öztürk | Ali Meşen | Yalçın Karaküçük

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.18 Issue 3, pp.7-12

Belge Tipi:

Makale

Yayın Tarihi:

11/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001303788

pISSN:

1303-6610

Uveit

specular microscopy

endothelial cell density

pleomorphism

polymegatism

central corneal thicknessÜveit

speküler mikroskobi

endotel hücre dansitesi

pleomrfizm

polimegatizm

santral korneal kalınlık

Sayı

Makale detayları

Yazarlar: Abdullah Beyoğlu | Banu Turgut Öztürk | Ali Meşen | Yalçın Karaküçük

Yayıncı: Kahramanmaras Sutcu Imam University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.18 Issue 3, pp.7-12

Belge Tipi: Makale

Yayın Tarihi: 11/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001303788

pISSN: 1303-6610

Sayı

Yazarlar:

Abdullah Beyoğlu | Banu Turgut Öztürk | Ali Meşen | Yalçın Karaküçük

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.18 Issue 3, pp.7-12

Belge Tipi:

Makale

Yayın Tarihi:

11/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001303788

pISSN:

1303-6610