Estimation of glucose level and body weight in Alloxan Induced Diabetic Rat treated with Aqueous extract of Garcinia Kola Seed

Chinwe Ewenighi

Makale detayları

Estimation of glucose level and body weight in Alloxan Induced Diabetic Rat treated with Aqueous extract of Garcinia Kola Seed

Yazarlar:

Chinwe Ewenighi

Yayıncı:

Kemal Türker ULUTAŞ

Dergi:

The Ulutas Medical Journal 2015 Vol.1 Issue 2, pp.26-30

Belge Tipi:

Makale

Yayın Tarihi:

1/2016

Belge Dili:

İngilizce

Document ID (Org No.):

2000802960

Sıklık:

Üç Aylık

eISSN:

2149-388X

pISSN:

2149-0430

Özet:

 


Aim: Hypoglyceamic effect of Garcinia kola (GK) was evaluated in alloxan induced diabetic rats.Method: Eighteen male wistar albino rats of weights between 158-172g were divided into three groups A- C. Group A was given distilled water (D/W) throughout the experiment; diabetes was induced in group B and C. Group B was given d/w but not GK while group C was treated with GK extract for 21 days. Fasting blood samples were collected at baseline, 24 hours, 7th, 14th and 21st day for blood glucose evaluation. Results: Mean fasting blood glucose (FBG) level was significantly higher (P<0.001) after 24 hours diabetes induction with alloxan in groups B and C rats compared to the baseline. Group B showed geometric increase in FBG level and decrease in body weight from 24 hours after diabetes induction to the 21st day of study duration. Group C rats had significantly lower (P<0.001) mean FBG level than Group B rats. Significant difference in body weight was observed among the 3 groups throughout the study periods but for baseline. Conclusion: Treatment of alloxan induced diabetic rats with GK extract lowers blood glucose level and restores weight loss.

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Makale detayları

Estimation of glucose level and body weight in Alloxan Induced Diabetic Rat treated with Aqueous extract of Garcinia Kola Seed

Yazarlar: Chinwe Ewenighi

Yayıncı: Kemal Türker ULUTAŞ

Dergi: The Ulutas Medical Journal 2015 Vol.1 Issue 2, pp.26-30

Belge Tipi: Makale

Yayın Tarihi: 1/2016

Belge Dili: İngilizce

Document ID (Org No.): 2000802960

Sıklık: Üç Aylık

eISSN: 2149-388X

pISSN: 2149-0430

Sayı

Yazarlar:

Chinwe Ewenighi

Yayıncı:

Kemal Türker ULUTAŞ

Dergi:

The Ulutas Medical Journal 2015 Vol.1 Issue 2, pp.26-30

Belge Tipi:

Makale

Yayın Tarihi:

1/2016

Belge Dili:

İngilizce

Document ID (Org No.):

2000802960

Sıklık:

Üç Aylık

eISSN:

2149-388X

pISSN:

2149-0430