Use of Baculovirus as Expression Vector in Biotechnology

Zihni DEMİRBAĞ; A. Osman BELDÜZ; İsmail DEMİR

Makale detayları

Use of Baculovirus as Expression Vector in Biotechnology

Yazarlar:

Zihni DEMİRBAĞ | A. Osman BELDÜZ | İsmail DEMİR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 1998 Vol.22 Issue 3, pp.249-262

Belge Tipi:

Makale

Yayın Tarihi:

2/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000814382

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Anahtar kelimeler:

Özet:

 

Variuos viral, bacterial, plant and animal proteins which are important for medicinal,  industrial and agricultural aspects, have been synhesized via expression vector systems have great  importance in biotechnology. Baculoviruses, used as a good model system in molecular biology  studies, a biological control agent in agriculture and an expression vector for synthesis of important  proteins, opened up a significant period for recombinant DNA technology and protein production.  Desired foreign genes, code for various products such as drug, toxin and nutrient substances, can be  replaced with viral genes which are not essasial for replication of baculovirus in cell culture. Priority  and advantages of baculoviruses, compare to other expression vectors, made them an important area  of biotehnology. However, the continuing studies to develop more effective expression vector and to  understand the molecular mechhanism of virus replication will make baculoviruses more signigicant  material of biotechnology in the future.

 

Variuos viral, bacterial, plant and animal proteins which are important for medicinal,  industrial and agricultural aspects, have been synhesized via expression vector systems have great  importance in biotechnology. Baculoviruses, used as a good model system in molecular biology  studies, a biological control agent in agriculture and an expression vector for synthesis of important  proteins, opened up a significant period for recombinant DNA technology and protein production.  Desired foreign genes, code for various products such as drug, toxin and nutrient substances, can be  replaced with viral genes which are not essasial for replication of baculovirus in cell culture. Priority  and advantages of baculoviruses, compare to other expression vectors, made them an important area  of biotehnology. However, the continuing studies to develop more effective expression vector and to  understand the molecular mechhanism of virus replication will make baculoviruses more signigicant  material of biotechnology in the future.

Makale detayları

Use of Baculovirus as Expression Vector in Biotechnology

Yazarlar: Zihni DEMİRBAĞ | A. Osman BELDÜZ | İsmail DEMİR

Yayıncı: TUBITAK

Dergi: Turkish Journal of Biology 1998 Vol.22 Issue 3, pp.249-262

Belge Tipi: Makale

Yayın Tarihi: 2/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000814382

Sıklık: İki Aylık

eISSN: 1303-6092

pISSN: 1300-0152

Baculovirus

expression vector

biotechnology

Sayı

Yazarlar:

Zihni DEMİRBAĞ | A. Osman BELDÜZ | İsmail DEMİR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 1998 Vol.22 Issue 3, pp.249-262

Belge Tipi:

Makale

Yayın Tarihi:

2/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000814382

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152