Chemoenzymatic Synthesis of 2-Bromo-6-Hydroxy-3-Methoxy-2-Cyclohexen-1-one

Emine Özgül KARAASLAN; Yasemin TOKA

Makale detayları

Chemoenzymatic Synthesis of 2-Bromo-6-Hydroxy-3-Methoxy-2-Cyclohexen-1-one

Yazarlar:

Emine Özgül KARAASLAN | Yasemin TOKA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2007 Vol.31 Issue 2, pp.149-153

Belge Tipi:

Makale

Yayın Tarihi:

1/2007

Belge Dili:

Türkçe

Document ID (Org No.):

2000728744

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

A chemoenzymatic synthesis of 2-bromo-6-hydroxy-3-methoxy-2-  cyclohexen-1-one starting from cyclohexane-1,3-dione is reported.   Manganese(III) acetate-mediated acetoxylation followed by the  enzyme-mediated hydrolysis of a'-acetoxy enone affords  hydroxy-enone 5 and acetoxy enone 4 with high enantiomeric excesses in  good yields.

 

A chemoenzymatic synthesis of 2-bromo-6-hydroxy-3-methoxy-2-  cyclohexen-1-one starting from cyclohexane-1,3-dione is reported.   Manganese(III) acetate-mediated acetoxylation followed by the  enzyme-mediated hydrolysis of a'-acetoxy enone affords  hydroxy-enone 5 and acetoxy enone 4 with high enantiomeric excesses in  good yields.

Makale detayları

Chemoenzymatic Synthesis of 2-Bromo-6-Hydroxy-3-Methoxy-2-Cyclohexen-1-one

Yazarlar: Emine Özgül KARAASLAN | Yasemin TOKA

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2007 Vol.31 Issue 2, pp.149-153

Belge Tipi: Makale

Yayın Tarihi: 1/2007

Belge Dili: Türkçe

Document ID (Org No.): 2000728744

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Emine Özgül KARAASLAN | Yasemin TOKA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2007 Vol.31 Issue 2, pp.149-153

Belge Tipi:

Makale

Yayın Tarihi:

1/2007

Belge Dili:

Türkçe

Document ID (Org No.):

2000728744

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527