Surgery for intractable temporal lobe epilepsy: experience of a single institution

Gökhan KURT; Mehmet TÖNGE; Emrah ÇELTİKÇİ; Irem ÇAPRAZ; Ayşe SERDAROĞLU; Erhan BİLİR

Makale detayları

Surgery for intractable temporal lobe epilepsy: experience of a single institution

Yazarlar:

Gökhan KURT | Mehmet TÖNGE | Emrah ÇELTİKÇİ | Irem ÇAPRAZ | Ayşe SERDAROĞLU | Erhan BİLİR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2014 Vol.44 Issue 5, pp.866-870

Belge Tipi:

Makale

Yayın Tarihi:

4/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000753105

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

In the treatment of epilepsy, encouraging results have been achieved with surgical treatment, especially for temporal lobe epilepsy (TLE). Drug resistance must be diagnosed as early as possible, because the ensuing seizures can be eliminated surgically via temporal lobe surgery in a high percentage (70%-90%) of patients. In this study we share our experience, in a single institution, of surgical treatment of intractable TLE.  Materials and methods: Between March 2006 and November 2010 we performed 127 corticoamygdalohippocampectomy (CAH) procedures. All CAH surgical procedures were done as described by Niemeyer's technique. Resection lengths were 4-4.5 cm from the temporal pole.  Results: At the end of 24 months, 79.7% (n = 94) patients were still on antiepileptic medications, with 55 of them on a decreased number or dose of drugs, and 20.3 (n = 24) patients were antiepileptic drug-free. Postoperative Engel's classes were 1, 2, and 3 in 87.2%, 5.08%, and 7.6%, respectively. There was no mortality in follow-up, and dysphasia in 1 patient (0.84%) was the only morbidity.  Conclusion: In our series we found that the outcome of surgery is associated with careful patient selection, which requires a detailed investigation of the patients. Our final conclusion is that outcome scores are independent of age, pathology, or sex but are dependent on correct patient selection.

 

In the treatment of epilepsy, encouraging results have been achieved with surgical treatment, especially for temporal lobe epilepsy (TLE). Drug resistance must be diagnosed as early as possible, because the ensuing seizures can be eliminated surgically via temporal lobe surgery in a high percentage (70%-90%) of patients. In this study we share our experience, in a single institution, of surgical treatment of intractable TLE.  Materials and methods: Between March 2006 and November 2010 we performed 127 corticoamygdalohippocampectomy (CAH) procedures. All CAH surgical procedures were done as described by Niemeyer's technique. Resection lengths were 4-4.5 cm from the temporal pole.  Results: At the end of 24 months, 79.7% (n = 94) patients were still on antiepileptic medications, with 55 of them on a decreased number or dose of drugs, and 20.3 (n = 24) patients were antiepileptic drug-free. Postoperative Engel's classes were 1, 2, and 3 in 87.2%, 5.08%, and 7.6%, respectively. There was no mortality in follow-up, and dysphasia in 1 patient (0.84%) was the only morbidity.  Conclusion: In our series we found that the outcome of surgery is associated with careful patient selection, which requires a detailed investigation of the patients. Our final conclusion is that outcome scores are independent of age, pathology, or sex but are dependent on correct patient selection.

Makale detayları

Surgery for intractable temporal lobe epilepsy: experience of a single institution

Yazarlar:

Gökhan KURT | Mehmet TÖNGE | Emrah ÇELTİKÇİ | Irem ÇAPRAZ | Ayşe SERDAROĞLU | Erhan BİLİR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2014 Vol.44 Issue 5, pp.866-870

Belge Tipi:

Makale

Yayın Tarihi:

4/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000753105

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Corticoamygdalohippocampectomy

epilepsy surgery

hippocampal sclerosis

mesial temporal lobe

outcome

temporal lobectomy

Sayı

Makale detayları

Surgery for intractable temporal lobe epilepsy: experience of a single institution

Yazarlar: Gökhan KURT | Mehmet TÖNGE | Emrah ÇELTİKÇİ | Irem ÇAPRAZ | Ayşe SERDAROĞLU | Erhan BİLİR

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2014 Vol.44 Issue 5, pp.866-870

Belge Tipi: Makale

Yayın Tarihi: 4/2014

Belge Dili: Türkçe

Document ID (Org No.): 2000753105

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Corticoamygdalohippocampectomy

epilepsy surgery

hippocampal sclerosis

mesial temporal lobe

outcome

temporal lobectomy

Sayı

Yazarlar:

Gökhan KURT | Mehmet TÖNGE | Emrah ÇELTİKÇİ | Irem ÇAPRAZ | Ayşe SERDAROĞLU | Erhan BİLİR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2014 Vol.44 Issue 5, pp.866-870

Belge Tipi:

Makale

Yayın Tarihi:

4/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000753105

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144