Investigation of the efficiency and safety of tilmicosin phosphate in treating experimental  mycoplasmal infections in pigs

Xiao-hui ZHANG; Jin-zhe PAN; Ning WU; Shu TANG; Xiang-dong LEI; Yang-yang SUN; Joerg HARTUNG; En-dong BAO

Makale detayları

Investigation of the efficiency and safety of tilmicosin phosphate in treating experimental mycoplasmal infections in pigs

Yazarlar:

Xiao-hui ZHANG | Jin-zhe PAN | Ning WU | Shu TANG | Xiang-dong LEI | Yang-yang SUN | Joerg HARTUNG | En-dong BAO

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2018 Vol.42 Issue 6, pp.571-580

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000764506

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Özet:

 


 
                         In order to evaluate the in vivo therapeutic effect of oral administration of tilmicosin phosphate on mycoplasmal pneumonia
in swine and its safety for the infected swine, the model of mycoplasmal pneumonia disease in swine was established by artificial
infection, and indices such as efficiency, cure rate, death rate, the score of lung lesion, and the routine blood tests, blood biochemistry,
and routine urine tests of tested swine were determined. The results showed that all of the dosage groups of 100 mg/L, 80 mg/L, 60 mg/L
of 10% tilmicosin phosphate soluble powder demonstrated distinct therapeutic effects on mycoplasmal pneumonia in pigs, significantly
reducing the scores of lung lesions in diseased pigs, and that the treatment effect of 60-80 mg/L tilmicosin phosphate soluble powder
was equivalent to that of 10% tilmicosin soluble powder. Administration of 10% tilmicosin phosphate soluble powder improved the
weight gain of the diseased swine. Treatment of infected pigs with 60?100 mg/L of 10% tilmicosin phosphate soluble powder did
not seem to influence the routine blood tests, biochemical index, and routine urine tests, and is therefore safe for diseased swine. In
conclusion, administration of 10% tilmicosin phosphate soluble powder is effective and safe to treat artificially infected swine with
mycoplasmal pneumonia.
                    

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Makale detayları

Investigation of the efficiency and safety of tilmicosin phosphate in treating experimental mycoplasmal infections in pigs

Yazarlar: Xiao-hui ZHANG | Jin-zhe PAN | Ning WU | Shu TANG | Xiang-dong LEI | Yang-yang SUN | Joerg HARTUNG | En-dong BAO

Yayıncı: TUBITAK

Dergi: Turkish Journal of Veterinary and Animal Sciences 2018 Vol.42 Issue 6, pp.571-580

Belge Tipi: Makale

Yayın Tarihi: 12/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000764506

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

Sayı

Yazarlar:

Xiao-hui ZHANG | Jin-zhe PAN | Ning WU | Shu TANG | Xiang-dong LEI | Yang-yang SUN | Joerg HARTUNG | En-dong BAO

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2018 Vol.42 Issue 6, pp.571-580

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000764506

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128