Novel biologically active glycosides from the aerial parts of Cephalaria gazipashensis

Nazlı Böke Sarikahya And Süheyla KIRMIZIGÜL

Makale detayları

Novel biologically active glycosides from the aerial parts of Cephalaria gazipashensis

Yazarlar:

Nazlı Böke Sarikahya And Süheyla KIRMIZIGÜL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2012 Vol.36 Issue 2, pp.323-334

Belge Tipi:

Makale

Yayın Tarihi:

1/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000727668

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

Two new triterpene glycosides, 3-O-b-D-glucopyranosyl-  (1\to 4)-b-D-xylopyranosyl-(1\to 3)-a-L-rhamnopyranosyl-  (1\to 3)-a-L-arabinopyranosyl olean-12-ene 28-O-b -D-  glucopyranosyl-(1\to 6)-b-D-glucopyranosyl ester (gazipashoside   A, 1) and 3-O-b-D-glucopyranosyl-(1\to 4)-b-D-xylopyranosyl-  (1\to 3)-a-L-rhamnopyranosyl-(1\to 2)-a-L-arabinopyranosyl  hederagenin 28-O-b -D-glucopyranosyl-(1\to 6)-b-D-glucopyranosyl  ester (gazipashoside B, 2), were isolated together with 11 known  compounds including 7 triterpene, 1 flavonoid, and 3 iridoidal  metabolites from the aerial parts of Cephalaria gazipashensis  (Dipsacaceae).  The structures of all compounds were elucidated by  extensive evaluation of the spectroscopic data (1D- and 2D- NMR,  HRESI-MS), as well as chemical examinations.  The antimicrobial  effects of all pure compounds were tested against gram-positive and  gram-negative bacteria.  The results indicated that the 2 new  triterpene glycosides might be acceptable as antimicrobial active  agents.

 

Two new triterpene glycosides, 3-O-b-D-glucopyranosyl-  (1\to 4)-b-D-xylopyranosyl-(1\to 3)-a-L-rhamnopyranosyl-  (1\to 3)-a-L-arabinopyranosyl olean-12-ene 28-O-b -D-  glucopyranosyl-(1\to 6)-b-D-glucopyranosyl ester (gazipashoside   A, 1) and 3-O-b-D-glucopyranosyl-(1\to 4)-b-D-xylopyranosyl-  (1\to 3)-a-L-rhamnopyranosyl-(1\to 2)-a-L-arabinopyranosyl  hederagenin 28-O-b -D-glucopyranosyl-(1\to 6)-b-D-glucopyranosyl  ester (gazipashoside B, 2), were isolated together with 11 known  compounds including 7 triterpene, 1 flavonoid, and 3 iridoidal  metabolites from the aerial parts of Cephalaria gazipashensis  (Dipsacaceae).  The structures of all compounds were elucidated by  extensive evaluation of the spectroscopic data (1D- and 2D- NMR,  HRESI-MS), as well as chemical examinations.  The antimicrobial  effects of all pure compounds were tested against gram-positive and  gram-negative bacteria.  The results indicated that the 2 new  triterpene glycosides might be acceptable as antimicrobial active  agents.

Makale detayları

Novel biologically active glycosides from the aerial parts of Cephalaria gazipashensis

Yazarlar: Nazlı Böke Sarikahya And Süheyla KIRMIZIGÜL

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2012 Vol.36 Issue 2, pp.323-334

Belge Tipi: Makale

Yayın Tarihi: 1/2012

Belge Dili: Türkçe

Document ID (Org No.): 2000727668

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Nazlı Böke Sarikahya And Süheyla KIRMIZIGÜL

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2012 Vol.36 Issue 2, pp.323-334

Belge Tipi:

Makale

Yayın Tarihi:

1/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000727668

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527