Evaluation of Cognitive Functions in Patients with Severely Obstructive Sleep Apnea Syndrome

Firdevs Ezgi Uçan Tokuç; Fatma Genç; Ömer Tarık Selçuk; Ruhsen Ocal; Aylin Yaman

Makale detayları

Evaluation of Cognitive Functions in Patients with Severely Obstructive Sleep Apnea Syndrome

Yazarlar:

Firdevs Ezgi Uçan Tokuç | Fatma Genç | Ömer Tarık Selçuk | Ruhsen Ocal | Aylin Yaman

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Batı Karadeniz Tıp Dergisi Vol.7 Issue 2, pp.219-224

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001297868

pISSN:

2822-4302

Anahtar kelimeler:

Özet:

 Aim: Obstructive sleep apnea syndrome OSAS, which is characterized by apnea due to recurrent upper respiratory tract obstruction and a decrease in oxygen saturation, is known to cause many neurocognitive disorders. In this study, we aimed to show the effect on cognitive functions that may develop in severe OSAS patients compared to the healthy control group. Material and Methods: We compared the cognitive status of 25 patients diagnosed with severe OSAS between 18 - 70 years with an all-night Polysomnographic PSG examination with 25 healthy voluntary control groups of similar age and gender. In both groups, patients who were previously diagnosed with cognitive dysfunction, who used drugs that would impair cognitive functions and who were diagnosed with a psychiatric disease were exclueded from the study. Rey Auditory Verbal Learning Test AVLT and Stroop Test were applied to the patient and control groups. Results: There was slowed responce time in Stroop-1, Stroop-2, Stroop-3, Stroop-4 and Stroop-Total tests mean  standard deviation: 13.35.3 second, 13.24 second, 18.17.1 second, 24.27.4 second, 100.829.7 second and p values: p0.031, p0.044, p0.013, p0.027, p0.032, respectively and also there was worsening in in AVLT B1, AVLT-Recognition tests  mean  standard deviation: 12.72.3 point, 3810.2 point and p values: p0.042, p0.001 respectively. As compared age, gender, comorbid disease with Stroop Test and AVLT there wasnt statistically significant in the OSAS group p0.05. Conclusion: Our findings confirm that attention and episodic memory can be significantly impaired using the Stroop and AVLT in patients with severe OSAS.

 Aim: Obstructive sleep apnea syndrome OSAS, which is characterized by apnea due to recurrent upper respiratory tract obstruction and a decrease in oxygen saturation, is known to cause many neurocognitive disorders. In this study, we aimed to show the effect on cognitive functions that may develop in severe OSAS patients compared to the healthy control group. Material and Methods: We compared the cognitive status of 25 patients diagnosed with severe OSAS between 18 - 70 years with an all-night Polysomnographic PSG examination with 25 healthy voluntary control groups of similar age and gender. In both groups, patients who were previously diagnosed with cognitive dysfunction, who used drugs that would impair cognitive functions and who were diagnosed with a psychiatric disease were exclueded from the study. Rey Auditory Verbal Learning Test AVLT and Stroop Test were applied to the patient and control groups. Results: There was slowed responce time in Stroop-1, Stroop-2, Stroop-3, Stroop-4 and Stroop-Total tests mean  standard deviation: 13.35.3 second, 13.24 second, 18.17.1 second, 24.27.4 second, 100.829.7 second and p values: p0.031, p0.044, p0.013, p0.027, p0.032, respectively and also there was worsening in in AVLT B1, AVLT-Recognition tests  mean  standard deviation: 12.72.3 point, 3810.2 point and p values: p0.042, p0.001 respectively. As compared age, gender, comorbid disease with Stroop Test and AVLT there wasnt statistically significant in the OSAS group p0.05. Conclusion: Our findings confirm that attention and episodic memory can be significantly impaired using the Stroop and AVLT in patients with severe OSAS.

 Aim: Obstructive sleep apnea syndrome OSAS, which is characterized by apnea due to recurrent upper respiratory tract obstruction and a decrease in oxygen saturation, is known to cause many neurocognitive disorders. In this study, we aimed to show the effect on cognitive functions that may develop in severe OSAS patients compared to the healthy control group. Material and Methods: We compared the cognitive status of 25 patients diagnosed with severe OSAS between 18 - 70 years with an all-night Polysomnographic PSG examination with 25 healthy voluntary control groups of similar age and gender. In both groups, patients who were previously diagnosed with cognitive dysfunction, who used drugs that would impair cognitive functions and who were diagnosed with a psychiatric disease were exclueded from the study. Rey Auditory Verbal Learning Test AVLT and Stroop Test were applied to the patient and control groups. Results: There was slowed responce time in Stroop-1, Stroop-2, Stroop-3, Stroop-4 and Stroop-Total tests mean  standard deviation: 13.35.3 second, 13.24 second, 18.17.1 second, 24.27.4 second, 100.829.7 second and p values: p0.031, p0.044, p0.013, p0.027, p0.032, respectively and also there was worsening in in AVLT B1, AVLT-Recognition tests  mean  standard deviation: 12.72.3 point, 3810.2 point and p values: p0.042, p0.001 respectively. As compared age, gender, comorbid disease with Stroop Test and AVLT there wasnt statistically significant in the OSAS group p0.05. Conclusion: Our findings confirm that attention and episodic memory can be significantly impaired using the Stroop and AVLT in patients with severe OSAS.

 Amaç: Üst solunum yolu obstrüksiyonuna bağlı apne ve oksijen satürasyonunda düşme ile karakterize obstrüktif uyku apne sendromunun OUAS bazı nörokognitif bozukluklara sebep olabileceği daha önceki çalışmalarda ileri sürülmüştür. Bu çalışmada sağlıklı kontrol grubuna kıyasla, ağır OUAS hastalarında gelişebilecek ileri kognitif fonksiyonları değerlendirmeyi amaçladık. Gereç ve Yöntemler: Polisomnografik PSG inceleme yapılmış olan hastalardan ağır OUAS tanısı alan 18-70 yaş arasındaki 25 hastaya ileri kognitif testler uygulandı. Olgular yaş ve cinsiyet uyumlu 25 sağlıklı kontrol grubu ile kıyaslandı. Hasta ve kontrol gruplarına; epizodik bellek ve öğrenmeyi değerlendirilmek için Rey İşitsel Sözel Öğrenme Testi Rey Auditory Verbal Learning Test, AVLT ile yürütücü fonksiyonlar ve dikkati değerlendirmek için Stroop Testi uygulandı. Bulgular: Gruplar arasında Stroop-1, Stroop-2, Stroop-3, Stroop-4 ve Stroop-Toplam sürelerinde sırası ile ortalama  standart sapma: 13,35,3 saniye, 13,24 saniye, 18,17,1 saniye, 24,27,4 saniye, 100,829,7 saniye ve p değerleri: p0.031, p0.044, p0.013, p0.027 ve p0.032 uzama, AVLT testinde ise AVLT B, AVLT Tanıma puanlarında düşüş izlendi sırası ile ortalama  standart sapma: 12,72,3 puan, 3810,2 puan ve p değerleri: p0.042, p0.001. OUAS grubunda yaş, cinsiyet ve komorbit hastalıklar ile Stroop Testi ve AVLT sonuçları karşılaştırıldığında istatistiksel olarak anlamlı bir farklılık saptanmadı p0.05. Sonuç: Çalışmamızda ağır derecede OUAS hastalarında Stroop Testi ve AVLT sonucuna göre dikkat ve epizodik belleğin belirgin şekilde bozulduğunu gösterdik.

Makale detayları

Evaluation of Cognitive Functions in Patients with Severely Obstructive Sleep Apnea Syndrome

Yazarlar:

Firdevs Ezgi Uçan Tokuç | Fatma Genç | Ömer Tarık Selçuk | Ruhsen Ocal | Aylin Yaman

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Batı Karadeniz Tıp Dergisi Vol.7 Issue 2, pp.219-224

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001297868

pISSN:

2822-4302

Cognitive dysfunction

obstructive sleep apnea syndrome

Rey auditory verbal learning test

stroop testKognitif disfonksiyon

obstrüktif uyku apne sendromu

rey işitsel sözel öğrenme testi

stroop testi

Sayı

Makale detayları

Yazarlar: Firdevs Ezgi Uçan Tokuç | Fatma Genç | Ömer Tarık Selçuk | Ruhsen Ocal | Aylin Yaman

Yayıncı: Zonguldak Bulent Ecevit University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Batı Karadeniz Tıp Dergisi Vol.7 Issue 2, pp.219-224

Belge Tipi: Makale

Yayın Tarihi: 8/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001297868

pISSN: 2822-4302

Sayı

Yazarlar:

Firdevs Ezgi Uçan Tokuç | Fatma Genç | Ömer Tarık Selçuk | Ruhsen Ocal | Aylin Yaman

Yayıncı:

Zonguldak Bulent Ecevit University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Batı Karadeniz Tıp Dergisi Vol.7 Issue 2, pp.219-224

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001297868

pISSN:

2822-4302