Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography

Hüseyin AKŞİT; Mehmet KEÇECİ; İbrahim DEMİRTAŞ; Nusret GENÇ

doi:https://doi.org/10.32571/ijct.577183

Makale detayları

Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography

Yazarlar:

Hüseyin AKŞİT | Mehmet KEÇECİ | İbrahim DEMİRTAŞ | Nusret GENÇ

Yayıncı:

İbrahim DEMİRTAŞ

Ana Başlıklar:

Kimya mühendisliği

Dergi:

International Journal of Chemistry and Technology 2019 Vol.3 Issue 1, pp.72-76

Belge Tipi:

Makale

Yayın Tarihi:

6/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000476857

Sıklık:

İki Yıllık

eISSN:

2602-277X

DOI:

https://doi.org/10.32571/ijct.577183

Özet:

 


In this study; it was aimed at
the isolation of rosmarinic acid (RosA) from Ocimum basilicum (OB) with
a selective extraction and rapid isolation technique using flash chromatography
(FC). For this purpose, dried leaves of OB were extracted with n-hexane,
dichloromethane, and methanol, respectively. The methanol extract (ME) was
extracted with dichloromethane and ethyl acetate using separation funnel by
suspending with water. The ethyl acetate layer was dried with anhydrous Na2SO4
and the solvent was evaporated to give a rosmarinic acid-rich extract. Then the
ethyl acetate extract (EAE) was separated over silica gel column using FC, and
thus RosA was isolated with high purity. 


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Makale detayları

Rapid isolation of rosmarinic acid from Ocimum basilicum using flash chromatography

Yazarlar: Hüseyin AKŞİT | Mehmet KEÇECİ | İbrahim DEMİRTAŞ | Nusret GENÇ

Yayıncı: İbrahim DEMİRTAŞ

Ana Başlıklar: Kimya mühendisliği

Dergi: International Journal of Chemistry and Technology 2019 Vol.3 Issue 1, pp.72-76

Belge Tipi: Makale

Yayın Tarihi: 6/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000476857

Sıklık: İki Yıllık

eISSN: 2602-277X

DOI: https://doi.org/10.32571/ijct.577183

Sayı

Yazarlar:

Hüseyin AKŞİT | Mehmet KEÇECİ | İbrahim DEMİRTAŞ | Nusret GENÇ

Yayıncı:

İbrahim DEMİRTAŞ

Ana Başlıklar:

Kimya mühendisliği

Dergi:

International Journal of Chemistry and Technology 2019 Vol.3 Issue 1, pp.72-76

Belge Tipi:

Makale

Yayın Tarihi:

6/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000476857

Sıklık:

İki Yıllık

eISSN:

2602-277X

DOI:

https://doi.org/10.32571/ijct.577183