Comparison of volatile profiles of Achillea sintenisii, an endemic species from Türkiye, and the evaluation of its essential oil's antibacterial and antibiofilm activities

Asli Can Agca; Nilüfer Vural; Sunasibel Rızvanoğlu; Müjde Eryılmaz

Makale detayları

Comparison of volatile profiles of Achillea sintenisii, an endemic species from Türkiye, and the evaluation of its essential oil's antibacterial and antibiofilm activities

Yazarlar:

Asli Can Agca | Nilüfer Vural | Sunasibel Rızvanoğlu | Müjde Eryılmaz

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmacognosy | Pharmaceutical Microbiology

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.548-560

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350176

pISSN:

2148-6905

Anahtar kelimeler:

Özet:

 Achillea sintenisii Hub-Mor is an endemic species in Türkiye, characterized by 110 capitula and ray flowers, and it thrives on calcareous rocks or gypsum-rich soils. This study aimed to determine the chemical composition and assess the antibacterial and antibiofilm activity of the essential oil of A. sintenisii AS-EO. The essential oil compounds of the flowering aerial part of A. sintenisii were extracted using both hydrodistillation and solid-phase microextraction SPME techniques and identified by gas chromatography-mass spectrometry GC-MS. Two different adsorbents were employed in the SPME approach. The yield of the essential oil of flowering aerial parts of A. sintenisii was 0,.4 hh. A total of 74, 112, and 78 compounds were identified from the samples obtained by hydrodistillation S1 and SPME extraction using the CAR-PDMS S2 and PDMS-DVB S3 adsorbents, respectively. The AS-EO exhibited the highest antibacterial activity against Staphylococcus aureus ATCC 25923 and S. aureus ATCC 43300 MRSA, with a minimum inhibitory concentration MIC of 1512 for each bacterium. This strong antibacterial effect may be attributed to the high content of 1,8-cineole and l-borneol. However, AS-EO did not exhibit any antibiofilm activity. These findings suggest that the essential oil of A. sintenisii has potential as a natural antibacterial agent, warranting further research to uncover its full potential.

 Achillea sintenisii Hub-Mor is an endemic species in Türkiye, characterized by 110 capitula and ray flowers, and it thrives on calcareous rocks or gypsum-rich soils. This study aimed to determine the chemical composition and assess the antibacterial and antibiofilm activity of the essential oil of A. sintenisii AS-EO. The essential oil compounds of the flowering aerial part of A. sintenisii were extracted using both hydrodistillation and solid-phase microextraction SPME techniques and identified by gas chromatography-mass spectrometry GC-MS. Two different adsorbents were employed in the SPME approach. The yield of the essential oil of flowering aerial parts of A. sintenisii was 0,.4 hh. A total of 74, 112, and 78 compounds were identified from the samples obtained by hydrodistillation S1 and SPME extraction using the CAR-PDMS S2 and PDMS-DVB S3 adsorbents, respectively. The AS-EO exhibited the highest antibacterial activity against Staphylococcus aureus ATCC 25923 and S. aureus ATCC 43300 MRSA, with a minimum inhibitory concentration MIC of 1512 for each bacterium. This strong antibacterial effect may be attributed to the high content of 1,8-cineole and l-borneol. However, AS-EO did not exhibit any antibiofilm activity. These findings suggest that the essential oil of A. sintenisii has potential as a natural antibacterial agent, warranting further research to uncover its full potential.

 Achillea sintenisii Hub-Mor is an endemic species in Türkiye, characterized by 110 capitula and ray flowers, and it thrives on calcareous rocks or gypsum-rich soils. This study aimed to determine the chemical composition and assess the antibacterial and antibiofilm activity of the essential oil of A. sintenisii AS-EO. The essential oil compounds of the flowering aerial part of A. sintenisii were extracted using both hydrodistillation and solid-phase microextraction SPME techniques and identified by gas chromatography-mass spectrometry GC-MS. Two different adsorbents were employed in the SPME approach. The yield of the essential oil of flowering aerial parts of A. sintenisii was 0,.4 hh. A total of 74, 112, and 78 compounds were identified from the samples obtained by hydrodistillation S1 and SPME extraction using the CAR-PDMS S2 and PDMS-DVB S3 adsorbents, respectively. The AS-EO exhibited the highest antibacterial activity against Staphylococcus aureus ATCC 25923 and S. aureus ATCC 43300 MRSA, with a minimum inhibitory concentration MIC of 1512 for each bacterium. This strong antibacterial effect may be attributed to the high content of 1,8-cineole and l-borneol. However, AS-EO did not exhibit any antibiofilm activity. These findings suggest that the essential oil of A. sintenisii has potential as a natural antibacterial agent, warranting further research to uncover its full potential.

 Achillea sintenisii Hub-Mor is an endemic species in Türkiye, characterized by 110 capitula and ray flowers, and it thrives on calcareous rocks or gypsum-rich soils. This study aimed to determine the chemical composition and assess the antibacterial and antibiofilm activity of the essential oil of A. sintenisii AS-EO. The essential oil compounds of the flowering aerial part of A. sintenisii were extracted using both hydrodistillation and solid-phase microextraction SPME techniques and identified by gas chromatography-mass spectrometry GC-MS. Two different adsorbents were employed in the SPME approach. The yield of the essential oil of flowering aerial parts of A. sintenisii was 0,.4 hh. A total of 74, 112, and 78 compounds were identified from the samples obtained by hydrodistillation S1 and SPME extraction using the CAR-PDMS S2 and PDMS-DVB S3 adsorbents, respectively. The AS-EO exhibited the highest antibacterial activity against Staphylococcus aureus ATCC 25923 and S. aureus ATCC 43300 MRSA, with a minimum inhibitory concentration MIC of 1512 for each bacterium. This strong antibacterial effect may be attributed to the high content of 1,8-cineole and l-borneol. However, AS-EO did not exhibit any antibiofilm activity. These findings suggest that the essential oil of A. sintenisii has potential as a natural antibacterial agent, warranting further research to uncover its full potential.

Makale detayları

Comparison of volatile profiles of Achillea sintenisii, an endemic species from Türkiye, and the evaluation of its essential oil's antibacterial and antibiofilm activities

Yazarlar:

Asli Can Agca | Nilüfer Vural | Sunasibel Rızvanoğlu | Müjde Eryılmaz

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmacognosy | Pharmaceutical Microbiology

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.548-560

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350176

pISSN:

2148-6905

Achillea sintenisii

Essential oil

HS-SPME

GC/MS

Antibacterial activity

Antibiofilm activityAchillea sintenisii

Essential oil

HS-SPME

GC/MS

Antibacterial activity

Antibiofilm activity

Sayı

Makale detayları

Yazarlar: Asli Can Agca | Nilüfer Vural | Sunasibel Rızvanoğlu | Müjde Eryılmaz

Yayıncı: İzzet KARA

Ana Başlıklar: Pharmacognosy | Pharmaceutical Microbiology

Dergi: International Journal of Secondary Metabolite Vol.12 Issue 3, pp.548-560

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001350176

pISSN: 2148-6905

Sayı

Yazarlar:

Asli Can Agca | Nilüfer Vural | Sunasibel Rızvanoğlu | Müjde Eryılmaz

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmacognosy | Pharmaceutical Microbiology

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.548-560

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350176

pISSN:

2148-6905