Increased Risk of Metabolic Syndrome in Patients with Vitiligo

Hatice ATAŞ; Müzeyyen GÖNÜL

Makale detayları

Increased Risk of Metabolic Syndrome in Patients with Vitiligo

Yazarlar:

Hatice ATAŞ | Müzeyyen GÖNÜL

Yayıncı:

Trakya University

Dergi:

Balkan Medical Journal 2017 Vol.34 Issue 3, pp.219-225

Belge Tipi:

Makale

Yayın Tarihi:

4/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000759164

Sıklık:

İki Aylık

pISSN:

2146-3123

Özet:

 

The risk of developing metabolic syndrome is increased in patients with vitiligo. The poor clinical features of vitiligo, such as active, extended and segmental vitiligo with an increased duration of time, are independent predictors for developing metabolic syndrome            Background: Inflammatory and immune processes can be triggered in vitiligo due to a decreased number of melanocytes and their anti-inflammatory effects. Because of the systemic nature of vitiligo, metabolic abnormalities such as insulin resistance and lipid profile disturbances as well as skin involvement may be observed in vitiligo.   Aims: To investigate the association between metabolic syndrome and vitiligo.   Study Design: Case-control study.   Methods: The demographic, clinical and laboratory features in the subjects were compared according to presence of vitiligo and metabolic syndrome [patients (n=63) vs. gender-age matched controls (n=65) and metabolic syndrome positive (n=38) vs. negative (n=90)]. A logistic regression analysis was also used.   Results: We identified metabolic syndrome in 24 (38.1%) subjects with vitiligo and 14 (21.5%) subjects without vitiligo (p=0.04). Active vitiligo, segmental vitiligo, an increased duration of vitiligo and an increased percentage in the affected body surface area were determined to be independent predictors of metabolic syndrome [activity of vitiligo: p=0.012, OR (95% CI)=64.4 (2.5-1672); type of vitiligo: p=0.007, OR (95% CI)=215.1 (4.3-10725.8); duration of vitiligo: p=0.03, OR (95% CI)=1.4 (1.1-2.0); percentage of affected body surface area: p=0.07, OR (95% CI)=1.2 (0.98-1.5)].   Conclusion: The risk of developing metabolic syndrome is increased in patients with vitiligo. The poor clinical features of vitiligo, such as active, extended and segmental vitiligo with an increased duration of time, are independent predictors for developing metabolic syndrome.

Makale detayları

Increased Risk of Metabolic Syndrome in Patients with Vitiligo

Yazarlar: Hatice ATAŞ | Müzeyyen GÖNÜL

Yayıncı: Trakya University

Dergi: Balkan Medical Journal 2017 Vol.34 Issue 3, pp.219-225

Belge Tipi: Makale

Yayın Tarihi: 4/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000759164

Sıklık: İki Aylık

pISSN: 2146-3123

Sayı

Yazarlar:

Hatice ATAŞ | Müzeyyen GÖNÜL

Yayıncı:

Trakya University

Dergi:

Balkan Medical Journal 2017 Vol.34 Issue 3, pp.219-225

Belge Tipi:

Makale

Yayın Tarihi:

4/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000759164

Sıklık:

İki Aylık

pISSN:

2146-3123