The association between vitamin D level and ICU mortality in COVID-19 patients: a single center survey

Sevda Onuk; Esma Eren

Makale detayları

The association between vitamin D level and ICU mortality in COVID-19 patients: a single center survey

Yazarlar:

Sevda Onuk | Esma Eren

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 2, pp.336-341

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286220

pISSN:

2636-8579

Anahtar kelimeler:

Özet:

 Aim: Vitamin D, an immune modulator, may contribute COVID-19 infection. This study aims to assess the relationship between vitamin D value and clinical outcomes need for mechanical ventilation MV support and intensive care unit ICU mortality in critically ill patients diagnosed with COVID-19. Material and Method: This study included critically ill adult patients diagnosed with COVID-19 infection. Serum vitamin D level was analyzed using liquid chromatography mass spectrometry. Vitamin D concentration was classified as normal 20 ngmL and deficiency 20 ngmL. The association between serum vitamin D value and the need for MV treatment and ICU mortality was analyzed by logistic regression model. Results: Ninety-six critically adult COVID-19 patients with were recruited. The mean age of patients was 68.812.6 years. The mean APACHE II score of participants was 14.56.7. A total of 69.8 of participants had vitamin D deficiency. Patients with deficiency of vitamin D had significantly higher procalcitonin, BUN and creatinine concentrations than patients with normal vitamin D value p0.031, p0.003, and p0.001, respectively. Serum vitamin D level was negatively weak correlated with SOFA score Rho-0.238, p0.020, serum creatinine Rho-0.299, p0.003 and troponin levels Rho-0.330, p0.004. Serum vitamin D value was not significantly associated with the need for MV support and ICU mortality p0.05. Conclusion: Approximately 70 of our study sample has below the normal range of serum vitamin D value. Low serum vitamin D concentrations were associated with increased SOFA, creatinine, and troponin concentrations in patients with COVID-19 infection. Vitamin D deficiency was not a predictor of need for MV support and ICU mortality in COVID-19 patients.

 Aim: Vitamin D, an immune modulator, may contribute COVID-19 infection. This study aims to assess the relationship between vitamin D value and clinical outcomes need for mechanical ventilation MV support and intensive care unit ICU mortality in critically ill patients diagnosed with COVID-19. Material and Method: This study included critically ill adult patients diagnosed with COVID-19 infection. Serum vitamin D level was analyzed using liquid chromatography mass spectrometry. Vitamin D concentration was classified as normal 20 ngmL and deficiency 20 ngmL. The association between serum vitamin D value and the need for MV treatment and ICU mortality was analyzed by logistic regression model. Results: Ninety-six critically adult COVID-19 patients with were recruited. The mean age of patients was 68.812.6 years. The mean APACHE II score of participants was 14.56.7. A total of 69.8 of participants had vitamin D deficiency. Patients with deficiency of vitamin D had significantly higher procalcitonin, BUN and creatinine concentrations than patients with normal vitamin D value p0.031, p0.003, and p0.001, respectively. Serum vitamin D level was negatively weak correlated with SOFA score Rho-0.238, p0.020, serum creatinine Rho-0.299, p0.003 and troponin levels Rho-0.330, p0.004. Serum vitamin D value was not significantly associated with the need for MV support and ICU mortality p0.05. Conclusion: Approximately 70 of our study sample has below the normal range of serum vitamin D value. Low serum vitamin D concentrations were associated with increased SOFA, creatinine, and troponin concentrations in patients with COVID-19 infection. Vitamin D deficiency was not a predictor of need for MV support and ICU mortality in COVID-19 patients.

 Aim: Vitamin D, an immune modulator, may contribute COVID-19 infection. This study aims to assess the relationship between vitamin D value and clinical outcomes need for mechanical ventilation MV support and intensive care unit ICU mortality in critically ill patients diagnosed with COVID-19. Material and Method: This study included critically ill adult patients diagnosed with COVID-19 infection. Serum vitamin D level was analyzed using liquid chromatography mass spectrometry. Vitamin D concentration was classified as normal 20 ngmL and deficiency 20 ngmL. The association between serum vitamin D value and the need for MV treatment and ICU mortality was analyzed by logistic regression model. Results: Ninety-six critically adult COVID-19 patients with were recruited. The mean age of patients was 68.812.6 years. The mean APACHE II score of participants was 14.56.7. A total of 69.8 of participants had vitamin D deficiency. Patients with deficiency of vitamin D had significantly higher procalcitonin, BUN and creatinine concentrations than patients with normal vitamin D value p0.031, p0.003, and p0.001, respectively. Serum vitamin D level was negatively weak correlated with SOFA score Rho-0.238, p0.020, serum creatinine Rho-0.299, p0.003 and troponin levels Rho-0.330, p0.004. Serum vitamin D value was not significantly associated with the need for MV support and ICU mortality p0.05. Conclusion: Approximately 70 of our study sample has below the normal range of serum vitamin D value. Low serum vitamin D concentrations were associated with increased SOFA, creatinine, and troponin concentrations in patients with COVID-19 infection. Vitamin D deficiency was not a predictor of need for MV support and ICU mortality in COVID-19 patients.

 Aim: Vitamin D, an immune modulator, may contribute COVID-19 infection. This study aims to assess the relationship between vitamin D value and clinical outcomes need for mechanical ventilation MV support and intensive care unit ICU mortality in critically ill patients diagnosed with COVID-19. Material and Method: This study included critically ill adult patients diagnosed with COVID-19 infection. Serum vitamin D level was analyzed using liquid chromatography mass spectrometry. Vitamin D concentration was classified as normal 20 ngmL and deficiency 20 ngmL. The association between serum vitamin D value and the need for MV treatment and ICU mortality was analyzed by logistic regression model. Results: Ninety-six critically adult COVID-19 patients with were recruited. The mean age of patients was 68.812.6 years. The mean APACHE II score of participants was 14.56.7. A total of 69.8 of participants had vitamin D deficiency. Patients with deficiency of vitamin D had significantly higher procalcitonin, BUN and creatinine concentrations than patients with normal vitamin D value p0.031, p0.003, and p0.001, respectively. Serum vitamin D level was negatively weak correlated with SOFA score Rho-0.238, p0.020, serum creatinine Rho-0.299, p0.003 and troponin levels Rho-0.330, p0.004. Serum vitamin D value was not significantly associated with the need for MV support and ICU mortality p0.05. Conclusion: Approximately 70 of our study sample has below the normal range of serum vitamin D value. Low serum vitamin D concentrations were associated with increased SOFA, creatinine, and troponin concentrations in patients with COVID-19 infection. Vitamin D deficiency was not a predictor of need for MV support and ICU mortality in COVID-19 patients.

Makale detayları

The association between vitamin D level and ICU mortality in COVID-19 patients: a single center survey

Yazarlar: Sevda Onuk | Esma Eren

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Journal of Health Sciences and Medicine Vol.6 Issue 2, pp.336-341

Belge Tipi: Makale

Yayın Tarihi: 3/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001286220

pISSN: 2636-8579

COVID-19

vitamin D

intensive care unit

mortality

Sayı

Yazarlar:

Sevda Onuk | Esma Eren

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 2, pp.336-341

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286220

pISSN:

2636-8579