Mid Term Evaluation of Patients Undergoing Surgery for Tetralogy of Fallot with 24 Hour Rhythm Holter and Cardiopulmonary Exercise Testing

Nazife Reyyan Gök; Figen Akalın; Elif Erolu

Makale detayları

Mid Term Evaluation of Patients Undergoing Surgery for Tetralogy of Fallot with 24 Hour Rhythm Holter and Cardiopulmonary Exercise Testing

Yazarlar:

Nazife Reyyan Gök | Figen Akalın | Elif Erolu

Yayıncı:

Sakarya University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Sakarya Tıp Dergisi Vol.15 Issue 1, pp.78-84

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343134

pISSN:

2146-409X

Anahtar kelimeler:

Özet:

 Objective: This study aimed to obtain mid-term evaluation of exercise capacity and arrhythmias with cardiopulmonary exercise testing CPET and 24-hour rhythm Holter in Tetralogy of Fallot TOF patients who underwent surgery. Materials and Methods: The study group consisted of patients over 6 years of age who had undergone complete correction surgery for TOF, while the control group consisted of healthy children of a similar age group who did not have any heart disease. Echocardiography, 24-hour Holter monitoring and CPET were applied to both groups. Results: Study group included 14 patients who were operated on due to TOF and 9 healthy children as the control group. During echocardiographic examination; aortic diameter, pulmonary annulus, right ventricular RV systolic and diastolic areas were found to be significantly larger in the patient group p0.044, p0.017, p0.05, p0.012 respectively. Myocardial performance index Tei index-MPI calculated from mitral and tricuspid valve annulus was found to be significantly higher in the patient group p0.05 for both. During CPET, stroke volume and VO2max levels were significantly smaller in patients p0.004, p0.044 respectively. Conclusion: Although operated TOF patients are asymptomatic in the mid-term, the exercise capacity in these patients is lower than in healthy individuals and this decrease is related to right ventricular size and dysfunction.

 Objective: This study aimed to obtain mid-term evaluation of exercise capacity and arrhythmias with cardiopulmonary exercise testing CPET and 24-hour rhythm Holter in Tetralogy of Fallot TOF patients who underwent surgery. Materials and Methods: The study group consisted of patients over 6 years of age who had undergone complete correction surgery for TOF, while the control group consisted of healthy children of a similar age group who did not have any heart disease. Echocardiography, 24-hour Holter monitoring and CPET were applied to both groups. Results: Study group included 14 patients who were operated on due to TOF and 9 healthy children as the control group. During echocardiographic examination; aortic diameter, pulmonary annulus, right ventricular RV systolic and diastolic areas were found to be significantly larger in the patient group p0.044, p0.017, p0.05, p0.012 respectively. Myocardial performance index Tei index-MPI calculated from mitral and tricuspid valve annulus was found to be significantly higher in the patient group p0.05 for both. During CPET, stroke volume and VO2max levels were significantly smaller in patients p0.004, p0.044 respectively. Conclusion: Although operated TOF patients are asymptomatic in the mid-term, the exercise capacity in these patients is lower than in healthy individuals and this decrease is related to right ventricular size and dysfunction.

 Objective: This study aimed to obtain mid-term evaluation of exercise capacity and arrhythmias with cardiopulmonary exercise testing CPET and 24-hour rhythm Holter in Tetralogy of Fallot TOF patients who underwent surgery. Materials and Methods: The study group consisted of patients over 6 years of age who had undergone complete correction surgery for TOF, while the control group consisted of healthy children of a similar age group who did not have any heart disease. Echocardiography, 24-hour Holter monitoring and CPET were applied to both groups. Results: Study group included 14 patients who were operated on due to TOF and 9 healthy children as the control group. During echocardiographic examination; aortic diameter, pulmonary annulus, right ventricular RV systolic and diastolic areas were found to be significantly larger in the patient group p0.044, p0.017, p0.05, p0.012 respectively. Myocardial performance index Tei index-MPI calculated from mitral and tricuspid valve annulus was found to be significantly higher in the patient group p0.05 for both. During CPET, stroke volume and VO2max levels were significantly smaller in patients p0.004, p0.044 respectively. Conclusion: Although operated TOF patients are asymptomatic in the mid-term, the exercise capacity in these patients is lower than in healthy individuals and this decrease is related to right ventricular size and dysfunction.

 Amaç: Bu çalışmada ameliyat edilen Fallot tetralojisi FT hastalarında egzersiz kapasitesinin ve aritmilerin kardiyopulmoner egzersiz testi KPET ve 24 saatlik ritim Holter ile orta dönemde değerlendirilmesi amaçlanmıştır. Gereç ve yöntemler: Çalışma grubu FT nedeniyle tam düzeltme ameliyatı geçirmiş 6 yaş üzerindeki hastalardan, kontrol grubu ise benzer yaş grubundaki herhangi bir kalp hastalığına sahip olmayan sağlıklı çocuklardan oluşturuldu. Her iki gruba ekokardiyografi, 24 saatlik Holter monitorizasyonu ve KPET uygulandı. Bulgular: Çalışmaya FT nedeniyle opere edilmiş 14 hasta ve kontrol grubu olarak da 9 sağlıklı çocuk alınmıştır. Hasta grubunda ekokardiyografik olarak aort çapı, pulmoner anulus, sağ ventrikül sistolik ve diyastolik alanları anlamlı olarak geniş bulunmuştur. Sırasıyla p0,044, p0,017, p0,05, p0,012 Mitral ve triküspit kapak anuluslarından hesaplanan miyokardiyal performans indeksi Tei indeksi- MPI hasta grubunda anlamlı olarak yüksek bulundu İkisi için p0,05. KPET sırasında, hasta grubunun atım hacmi ve VO2max düzeyleri kontrol grubundan anlamlı olarak düşük bulunmuştur Sırasıyla p0,004, p0,044. Sonuç: Opere edilmiş FT hastaları orta dönemde asemptomatik olsalar da bu hastalardaki egzersiz kapasitesi sağlıklı bireylere göre düşüktür ve bu düşüklük sağ ventrikül boyutu ve disfonksiyonu ile ilişkilidir.

Makale detayları

Mid Term Evaluation of Patients Undergoing Surgery for Tetralogy of Fallot with 24 Hour Rhythm Holter and Cardiopulmonary Exercise Testing

Yazarlar:

Nazife Reyyan Gök | Figen Akalın | Elif Erolu

Yayıncı:

Sakarya University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Sakarya Tıp Dergisi Vol.15 Issue 1, pp.78-84

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343134

pISSN:

2146-409X

Tetralogy of Fallot

Exercise Capacity

ArrhythmiaFallot tetralojisi

Egzersiz Kapasitesi

Aritmi

Sayı

Makale detayları

Mid Term Evaluation of Patients Undergoing Surgery for Tetralogy of Fallot with 24 Hour Rhythm Holter and Cardiopulmonary Exercise Testing

Yazarlar: Nazife Reyyan Gök | Figen Akalın | Elif Erolu

Yayıncı: Sakarya University

Ana Başlıklar: Klinik Tıp Bilimleri (Diğer)

Dergi: Sakarya Tıp Dergisi Vol.15 Issue 1, pp.78-84

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001343134

pISSN: 2146-409X

Tetralogy of Fallot

Exercise Capacity

ArrhythmiaFallot tetralojisi

Egzersiz Kapasitesi

Aritmi

Sayı

Yazarlar:

Nazife Reyyan Gök | Figen Akalın | Elif Erolu

Yayıncı:

Sakarya University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Sakarya Tıp Dergisi Vol.15 Issue 1, pp.78-84

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343134

pISSN:

2146-409X