The pregnancy results were not affected from the administration day of Depot GnRH agonists in artificial cycle frozen-thawed embryo transfers

Mehmet Ağar; Asena Ayar Madenli; Nur Dokuzeylül Güngör; Şebnem Alanya Tosun

Makale detayları

The pregnancy results were not affected from the administration day of Depot GnRH agonists in artificial cycle frozen-thawed embryo transfers

Yazarlar:

Mehmet Ağar | Asena Ayar Madenli | Nur Dokuzeylül Güngör | Şebnem Alanya Tosun

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 2, pp.89-93

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286119

pISSN:

2717-7505

Anahtar kelimeler:

Özet:

 Aim: In frozen-thawed embryo transfers FET, Gonadotropin-Releasing Hormone GnRH agonists have recently been used to improve implantation results. It is preferred to administer it in the luteal phase of the previous cycle. The objective was to compare the effects of different administration days of depot GnRH agonists on implantation and pregnancy rates in the artificial cycle of FET. Material and Method: A retrospective case-control study was conducted in an in vitro fertilization IVF center in a university hospital, including all women starting an artificial cycle of FET. One thousand two hundred and twenty-seven n:1227 FET cycles were scanned from the files from October 2014 to December 2021. Depot agonists Lucrin depot 3.75 mg sc Abbott USA.-leuprolide acetate were used in 219 patients with endometriosis. In 58 patients, it was administered on day 21 of the previous cycle Group 1, and in 161 patients, it was administered on day 2 of the same cycle Group 2. Results: This study showed no statistically significant difference between the two groups in laboratory parameters and endometrial thickness p0.05. There was no statistically significant association between the abort rate and transfer day p0.05. There was no statistically significant association between the pregnancy results and transfer day p0.05. The ongoing pregnancy rate OPR rate was relatively high in the second group compared to the twenty-first day of the previous cycle 8716154 vs. 3058 51.7. The biochemical pregnancy was relatively high in the second-day group compared to the twenty-first day of the previous cycle 6216138.5 vs. 2158 36.2. The abort rate was relatively high in the twenty-first-day group compared to the second day of the cycle 258728.75 vs. 93030. Conclusion: In conclusion, the impacts of various administration days of depot Gonadotropin-releasing hormone GnRH agonists on implantation and pregnancy rates were not statistically significant.

 Aim: In frozen-thawed embryo transfers FET, Gonadotropin-Releasing Hormone GnRH agonists have recently been used to improve implantation results. It is preferred to administer it in the luteal phase of the previous cycle. The objective was to compare the effects of different administration days of depot GnRH agonists on implantation and pregnancy rates in the artificial cycle of FET. Material and Method: A retrospective case-control study was conducted in an in vitro fertilization IVF center in a university hospital, including all women starting an artificial cycle of FET. One thousand two hundred and twenty-seven n:1227 FET cycles were scanned from the files from October 2014 to December 2021. Depot agonists Lucrin depot 3.75 mg sc Abbott USA.-leuprolide acetate were used in 219 patients with endometriosis. In 58 patients, it was administered on day 21 of the previous cycle Group 1, and in 161 patients, it was administered on day 2 of the same cycle Group 2. Results: This study showed no statistically significant difference between the two groups in laboratory parameters and endometrial thickness p0.05. There was no statistically significant association between the abort rate and transfer day p0.05. There was no statistically significant association between the pregnancy results and transfer day p0.05. The ongoing pregnancy rate OPR rate was relatively high in the second group compared to the twenty-first day of the previous cycle 8716154 vs. 3058 51.7. The biochemical pregnancy was relatively high in the second-day group compared to the twenty-first day of the previous cycle 6216138.5 vs. 2158 36.2. The abort rate was relatively high in the twenty-first-day group compared to the second day of the cycle 258728.75 vs. 93030. Conclusion: In conclusion, the impacts of various administration days of depot Gonadotropin-releasing hormone GnRH agonists on implantation and pregnancy rates were not statistically significant.

 Aim: In frozen-thawed embryo transfers FET, Gonadotropin-Releasing Hormone GnRH agonists have recently been used to improve implantation results. It is preferred to administer it in the luteal phase of the previous cycle. The objective was to compare the effects of different administration days of depot GnRH agonists on implantation and pregnancy rates in the artificial cycle of FET. Material and Method: A retrospective case-control study was conducted in an in vitro fertilization IVF center in a university hospital, including all women starting an artificial cycle of FET. One thousand two hundred and twenty-seven n:1227 FET cycles were scanned from the files from October 2014 to December 2021. Depot agonists Lucrin depot 3.75 mg sc Abbott USA.-leuprolide acetate were used in 219 patients with endometriosis. In 58 patients, it was administered on day 21 of the previous cycle Group 1, and in 161 patients, it was administered on day 2 of the same cycle Group 2. Results: This study showed no statistically significant difference between the two groups in laboratory parameters and endometrial thickness p0.05. There was no statistically significant association between the abort rate and transfer day p0.05. There was no statistically significant association between the pregnancy results and transfer day p0.05. The ongoing pregnancy rate OPR rate was relatively high in the second group compared to the twenty-first day of the previous cycle 8716154 vs. 3058 51.7. The biochemical pregnancy was relatively high in the second-day group compared to the twenty-first day of the previous cycle 6216138.5 vs. 2158 36.2. The abort rate was relatively high in the twenty-first-day group compared to the second day of the cycle 258728.75 vs. 93030. Conclusion: In conclusion, the impacts of various administration days of depot Gonadotropin-releasing hormone GnRH agonists on implantation and pregnancy rates were not statistically significant.

 Aim: In frozen-thawed embryo transfers FET, Gonadotropin-Releasing Hormone GnRH agonists have recently been used to improve implantation results. It is preferred to administer it in the luteal phase of the previous cycle. The objective was to compare the effects of different administration days of depot GnRH agonists on implantation and pregnancy rates in the artificial cycle of FET. Material and Methods: A retrospective case-control study was conducted in an in vitro fertilization IVF center in a university hospital including all women starting an artificial cycle of FET. One thousand two hundred and twenty-seven n:1227 FET cycles were scanned from the files from October 2014 to December 2021. Depot agonists Lucrin depot 3.75 mg sc Abbott USA.-leuprolide acetate were used in 219 patients with endometriosis. In 58 patients it was administered at day 21 on the previous cycle Group 1 and on 161 patients it was administered at day 2 of the same cycle Group 2. Results: This study showed no statistically significant difference between the two groups in laboratory parameters and endometrial thickness p0.05. There was not a statistically significant association between the abort rate and transfer day p0.05. There was not a statistically significant association between the pregnancy results and transfer day p0.05. The ongoing pregnancy rate OPR rate was relatively high in the second group compared to the twenty-first day of the previous cycle 8716154 vs. 3058 51.7. The biochemical pregnancy was relatively high in the second-day group compared to the twenty-first day of the previous cycle 6216138.5 vs. 2158 36.2. The abort rate was relatively high in the twenty-first-day group compared to the second-day of the cycle 258728.75 vs. 93030. Conclusion: In conclusion, the impacts of various administration days of depot Gonadotropin-releasing hormone GnRH agonists on implantation and pregnancy rates were not statistically significant.

Makale detayları

The pregnancy results were not affected from the administration day of Depot GnRH agonists in artificial cycle frozen-thawed embryo transfers

Yazarlar:

Mehmet Ağar | Asena Ayar Madenli | Nur Dokuzeylül Güngör | Şebnem Alanya Tosun

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 2, pp.89-93

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286119

pISSN:

2717-7505

Assisted reproduction technology

FET cycle

GnRH agonist

implantation

Assisted reproduction technology; Frozen-thawed embryo transfer cycle; GnRH agonists; Implantation

Assisted reproduction technology

FET cycle

GnRH agonist

implantation

Sayı

Makale detayları

Yazarlar: Mehmet Ağar | Asena Ayar Madenli | Nur Dokuzeylül Güngör | Şebnem Alanya Tosun

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Journal of Medicine and Palliative Care Vol.4 Issue 2, pp.89-93

Belge Tipi: Makale

Yayın Tarihi: 3/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001286119

pISSN: 2717-7505

Sayı

Yazarlar:

Mehmet Ağar | Asena Ayar Madenli | Nur Dokuzeylül Güngör | Şebnem Alanya Tosun

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 2, pp.89-93

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286119

pISSN:

2717-7505