Could RDW and MPV Be a Predictor of Disease Severity and Mortality in Acute Pancreatitis?

Vedat Tan; Berat Ebik; Ferhat Bacaksız; Ali Üzel; Mustafa Zanyar Akkuzu; Ahmet Yavuz; Ümit Karabulut

Makale detayları

Could RDW and MPV Be a Predictor of Disease Severity and Mortality in Acute Pancreatitis?

Yazarlar:

Vedat Tan | Berat Ebik | Ferhat Bacaksız | Ali Üzel | Mustafa Zanyar Akkuzu | Ahmet Yavuz | Ümit Karabulut

Yayıncı:

Harran University

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.21 Issue 1, pp.6-10

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001313101

pISSN:

1304-9623

Anahtar kelimeler:

Özet:

 Background: Background: In acute pancreatitis AP, determining the severity of the disease starting from hospitalization is important for planning the treatment. Data obtained in previous studies that examining the clinical importance of RDW Erythrocyte Distribution Volume and MPV Mean Plate-let Volume levels in patients with AP are contradictory. Our aim in this study is to determine whether RDW and MPV levels can predict the severity of pancreatitis and related mortality. Materials and Methods: The data of 262 patients hospitalized due to AP between 2019 and 2022 were retrospectively examined. Patients were divided into groups according to Atlanta crite-ria.Then, the relationship between RDW and MPV values and the severity and prognosis of pancrea-titis was examined statistically. Results: While 83.9 n220 of the patients had mild pancreatitis, 16.1 n42 had severe pan-creatitis. While the mean RDW index was 42.56.9 fL in patients with mild AP, it was 42.06.6 fL in severe AP patients and there was no significant difference between the two groups p0.625. In addition, there was no significant difference between the two groups in terms of mean MPV level 9.71.0 fL vs 9.81.3 Fl, p0.687. ROC analysis showed that there was no significant and critical MPV and RDW threshold value to detect the severity of pancreatitis AUC values: 0.499 and 0.453, respectively. Conclusions: In our study, we found that there was no significant difference in terms of RDW and MPV in patients with mild and severe pancreatitis according to the Atlanta criteria. Therefore, we can say that MPV and RDW levels are not sufficient and strong parameters to predict the severity and prognosis of pancreatitis. Key Words: Acute Pancreatitis, Red Cell Distribution Width RDW, Mean Platelet Volume MPV.

 Background: Background: In acute pancreatitis AP, determining the severity of the disease starting from hospitalization is important for planning the treatment. Data obtained in previous studies that examining the clinical importance of RDW Erythrocyte Distribution Volume and MPV Mean Plate-let Volume levels in patients with AP are contradictory. Our aim in this study is to determine whether RDW and MPV levels can predict the severity of pancreatitis and related mortality. Materials and Methods: The data of 262 patients hospitalized due to AP between 2019 and 2022 were retrospectively examined. Patients were divided into groups according to Atlanta crite-ria.Then, the relationship between RDW and MPV values and the severity and prognosis of pancrea-titis was examined statistically. Results: While 83.9 n220 of the patients had mild pancreatitis, 16.1 n42 had severe pan-creatitis. While the mean RDW index was 42.56.9 fL in patients with mild AP, it was 42.06.6 fL in severe AP patients and there was no significant difference between the two groups p0.625. In addition, there was no significant difference between the two groups in terms of mean MPV level 9.71.0 fL vs 9.81.3 Fl, p0.687. ROC analysis showed that there was no significant and critical MPV and RDW threshold value to detect the severity of pancreatitis AUC values: 0.499 and 0.453, respectively. Conclusions: In our study, we found that there was no significant difference in terms of RDW and MPV in patients with mild and severe pancreatitis according to the Atlanta criteria. Therefore, we can say that MPV and RDW levels are not sufficient and strong parameters to predict the severity and prognosis of pancreatitis. Key Words: Acute Pancreatitis, Red Cell Distribution Width RDW, Mean Platelet Volume MPV.

 Background: Background: In acute pancreatitis AP, determining the severity of the disease starting from hospitalization is important for planning the treatment. Data obtained in previous studies that examining the clinical importance of RDW Erythrocyte Distribution Volume and MPV Mean Plate-let Volume levels in patients with AP are contradictory. Our aim in this study is to determine whether RDW and MPV levels can predict the severity of pancreatitis and related mortality. Materials and Methods: The data of 262 patients hospitalized due to AP between 2019 and 2022 were retrospectively examined. Patients were divided into groups according to Atlanta crite-ria.Then, the relationship between RDW and MPV values and the severity and prognosis of pancrea-titis was examined statistically. Results: While 83.9 n220 of the patients had mild pancreatitis, 16.1 n42 had severe pan-creatitis. While the mean RDW index was 42.56.9 fL in patients with mild AP, it was 42.06.6 fL in severe AP patients and there was no significant difference between the two groups p0.625. In addition, there was no significant difference between the two groups in terms of mean MPV level 9.71.0 fL vs 9.81.3 Fl, p0.687. ROC analysis showed that there was no significant and critical MPV and RDW threshold value to detect the severity of pancreatitis AUC values: 0.499 and 0.453, respectively. Conclusions: In our study, we found that there was no significant difference in terms of RDW and MPV in patients with mild and severe pancreatitis according to the Atlanta criteria. Therefore, we can say that MPV and RDW levels are not sufficient and strong parameters to predict the severity and prognosis of pancreatitis. Key Words: Acute Pancreatitis, Red Cell Distribution Width RDW, Mean Platelet Volume MPV.

 Amaç: Akut pankreatit AP tanısıyla hastaneye yatırılan hastalarda yatıştan itibaren hastalığın şiddetini belirlemek tedavinin planlaması için büyük önem arz etmektedir. RDW Eritrosit Dağılım Hacmi ve MPVnin Ortalama Trombosit Hacmi pankreatitin şiddetini öngörebilme özelliğinin olup olmadığını araştırmak amacıyla bu çalışmayı yaptık. Materyal ve metod: 2019-2022 yılları arasında AP nedeniyle hastaneye yatırılan 262 hastanın verileri retrospektif olarak incelendi. Hastalar Atlanta kriterleri referans alınarak pankreatitin şiddetine göre gruplara ayrıldı. Daha sonra RDW ve MPV değerlerinin pankreatitin şiddeti ve prognozuyla ilişkisi istatistiksel olarak incelendi. Bulgular: APli hastaların 83.9u n220 hafif; 16.1i n42 şiddetli pankreatit idi. Ortalama RDW indeksi hafif APli hastalarda 42.56.9 fL iken, şiddetli AP hastalarında 42.06.6 fL idi p0.625. Ortalama MPV seviyesi açısından da her iki grup arasında anlamlı bir farklılık saptanmadı 9.71.0 fL vs 9.81.3 Fl, p0.687. Yapılan ROC analizi pankreatitin şiddetini saptayacak anlamlı ve kritik bir MPV ve RDW eşik değerinin olmadığını gösterdi AUC MPV: 0.499; AUC RDW:0.453. Sonuç: AP nedeniyle hastaneye yatırılan ve takipleri sırasında Atlanta kriterlerine göre şiddetli pankreatit gelişen hastaların RDW ve MPV seviyesinin hafif pankreatitli hastalardan farklı olmadığını belirledik. APli hastalarda MPV ve RDW seviyesinin pankreatitin şiddetini ve prognozunu öngörmede yeterli ve güçlü bir parametre olmadığını söyleyebiliriz.

Makale detayları

Could RDW and MPV Be a Predictor of Disease Severity and Mortality in Acute Pancreatitis?

Yazarlar:

Vedat Tan | Berat Ebik | Ferhat Bacaksız | Ali Üzel | Mustafa Zanyar Akkuzu | Ahmet Yavuz | Ümit Karabulut

Yayıncı:

Harran University

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.21 Issue 1, pp.6-10

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001313101

pISSN:

1304-9623

Akut Pankreatit

Eritrosit Dağılım Genişliği (RDW)

Ortalama Trombosit Hacmi (MPV)

Sayı

Makale detayları

Could RDW and MPV Be a Predictor of Disease Severity and Mortality in Acute Pancreatitis?

Yazarlar: Vedat Tan | Berat Ebik | Ferhat Bacaksız | Ali Üzel | Mustafa Zanyar Akkuzu | Ahmet Yavuz | Ümit Karabulut

Yayıncı: Harran University

Ana Başlıklar: Gastroenteroloji ve Hepatoloji

Dergi: Harran Üniversitesi Tıp Fakültesi Dergisi Vol.21 Issue 1, pp.6-10

Belge Tipi: Makale

Yayın Tarihi: 4/2024

Belge Dili: Türkçe

Document ID (Org No.): 2001313101

pISSN: 1304-9623

Akut Pankreatit

Eritrosit Dağılım Genişliği (RDW)

Ortalama Trombosit Hacmi (MPV)

Sayı

Yazarlar:

Vedat Tan | Berat Ebik | Ferhat Bacaksız | Ali Üzel | Mustafa Zanyar Akkuzu | Ahmet Yavuz | Ümit Karabulut

Yayıncı:

Harran University

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.21 Issue 1, pp.6-10

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001313101

pISSN:

1304-9623