Identification and Characterization of the Rat DVL2 Gene Using Bioinformatic Tools

Lokman VARIŞLI; Osman ÇEN

Makale detayları

Identification and Characterization of the Rat DVL2 Gene Using Bioinformatic Tools

Yazarlar:

Lokman VARIŞLI | Osman ÇEN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2007 Vol.31 Issue 2, pp.81-86

Belge Tipi:

Makale

Yayın Tarihi:

1/2007

Belge Dili:

Türkçe

Document ID (Org No.):

2000813285

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Anahtar kelimeler:

Özet:

 

We identified and characterized the rat DVL2 gene using bioinformatics. In addition to the structure and chromosomal localization of the rat DVL2 gene, the transcribed and translated protein product of the gene was analyzed in silico. Results showed that the rat DVL2 gene consists of 15 exons and is located on the rat genomic contig WGA1854.3 on chromosome 10. Database searches using the rat DVL2 amino acid sequence as a query showed a number of homologous protein sequences in different species, including M. musculus, P. troglodytes, C. familiaris, H. sapiens, B. taurus, D. rerio, X. laevis, and T. nigroviridis. DAX, PDZ signaling, and DEP-conserved domain structures were identified within the rat DVL2 protein.

 

We identified and characterized the rat DVL2 gene using bioinformatics. In addition to the structure and chromosomal localization of the rat DVL2 gene, the transcribed and translated protein product of the gene was analyzed in silico. Results showed that the rat DVL2 gene consists of 15 exons and is located on the rat genomic contig WGA1854.3 on chromosome 10. Database searches using the rat DVL2 amino acid sequence as a query showed a number of homologous protein sequences in different species, including M. musculus, P. troglodytes, C. familiaris, H. sapiens, B. taurus, D. rerio, X. laevis, and T. nigroviridis. DAX, PDZ signaling, and DEP-conserved domain structures were identified within the rat DVL2 protein.

Makale detayları

Identification and Characterization of the Rat DVL2 Gene Using Bioinformatic Tools

Yazarlar:

Lokman VARIŞLI | Osman ÇEN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2007 Vol.31 Issue 2, pp.81-86

Belge Tipi:

Makale

Yayın Tarihi:

1/2007

Belge Dili:

Türkçe

Document ID (Org No.):

2000813285

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Bioinformatics

DVL2

rat genome

Wnt signaling

Sayı

Makale detayları

Identification and Characterization of the Rat DVL2 Gene Using Bioinformatic Tools

Yazarlar: Lokman VARIŞLI | Osman ÇEN

Yayıncı: TUBITAK

Dergi: Turkish Journal of Biology 2007 Vol.31 Issue 2, pp.81-86

Belge Tipi: Makale

Yayın Tarihi: 1/2007

Belge Dili: Türkçe

Document ID (Org No.): 2000813285

Sıklık: İki Aylık

eISSN: 1303-6092

pISSN: 1300-0152

Bioinformatics

DVL2

rat genome

Wnt signaling

Sayı

Yazarlar:

Lokman VARIŞLI | Osman ÇEN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2007 Vol.31 Issue 2, pp.81-86

Belge Tipi:

Makale

Yayın Tarihi:

1/2007

Belge Dili:

Türkçe

Document ID (Org No.):

2000813285

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152