Synthesis and Spectroscopic Properties of Optical Probe Based on Schiff Base with Biological Application

Mevlüt BAYRAKCI; Bahar YILMAZ

doi:https://doi.org/10.21597/jist.679021

Makale detayları

Synthesis and Spectroscopic Properties of Optical Probe Based on Schiff Base with Biological Application

Yazarlar:

Mevlüt BAYRAKCI | Bahar YILMAZ

Yayıncı:

Igdir University

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Journal of the Institute of Science and Technology 2020 Vol.10 Issue 3, pp.1767-1778

Belge Tipi:

Makale

Yayın Tarihi:

8/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000463798

Sıklık:

Üç Aylık

eISSN:

2536-4618

DOI:

https://doi.org/10.21597/jist.679021

Özet:

 

A series of facile optical probe has been easily developed by a one-step Schiff base type reaction of 2,4-dihydroxybenzaldehyde and ortho, meta or para aminophenol. Schiff base compounds as fluorescence sensor were utilized to identify metal ions by spectrophotometric techniques. The data of absorption and emission spectra displayed the extraordinary selective and sensitive sensor properties for Schiff base probe derived from ortho aminophenol (SB-2) toward Al3+ ions. Upon introducing Al3+ ions, an excellent increase in the fluorescence intensity of the probe (SB-2) resulting in color change was observed because of blocking the photoinduced electron transfer (PET) mechanism of azomethine unit. The specific bonding mode of probe (SB-2) with Al3+ was verified by using a series of spectroscopic techniques such as FT-IR, 1H NMR, and UV-vis (Job-plot data). The detection limit of probe (SB-2) toward Al3+was determined around 10−7M. Furthermore, cell imaging studies of probe (SB-2) were also performed and from these experiments, it was seen that the presence of even trace amounts of Al3+ in living cells could be noticeably detected by (SB-2). In this study, antimicrobial properties of Schiff base compounds were also carried out towards some selected bacteria species. This presented work provides a method for design, facile synthesis and application of effective fluorescence probes toward Al3+ ions in biological systems.

 

A series of facile optical probe has been easily developed by a one-step Schiff base type reaction of 2,4-dihydroxybenzaldehyde and ortho, meta or para aminophenol. Schiff base compounds as fluorescence sensor were utilized to identify metal ions by spectrophotometric techniques. The data of absorption and emission spectra displayed the extraordinary selective and sensitive sensor properties for Schiff base probe derived from ortho aminophenol (SB-2) toward Al3+ ions. Upon introducing Al3+ ions, an excellent increase in the fluorescence intensity of the probe (SB-2) resulting in color change was observed because of blocking the photoinduced electron transfer (PET) mechanism of azomethine unit. The specific bonding mode of probe (SB-2) with Al3+ was verified by using a series of spectroscopic techniques such as FT-IR, 1H NMR, and UV-vis (Job-plot data). The detection limit of probe (SB-2) toward Al3+was determined around 10−7M. Furthermore, cell imaging studies of probe (SB-2) were also performed and from these experiments, it was seen that the presence of even trace amounts of Al3+ in living cells could be noticeably detected by (SB-2). In this study, antimicrobial properties of Schiff base compounds were also carried out towards some selected bacteria species. This presented work provides a method for design, facile synthesis and application of effective fluorescence probes toward Al3+ ions in biological systems.

Makale detayları

Synthesis and Spectroscopic Properties of Optical Probe Based on Schiff Base with Biological Application

Yazarlar: Mevlüt BAYRAKCI | Bahar YILMAZ

Yayıncı: Igdir University

Ana Başlıklar: Kimya mühendisliği

Dergi: Journal of the Institute of Science and Technology 2020 Vol.10 Issue 3, pp.1767-1778

Belge Tipi: Makale

Yayın Tarihi: 8/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000463798

Sıklık: Üç Aylık

eISSN: 2536-4618

DOI: https://doi.org/10.21597/jist.679021

Sayı

Yazarlar:

Mevlüt BAYRAKCI | Bahar YILMAZ

Yayıncı:

Igdir University

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Journal of the Institute of Science and Technology 2020 Vol.10 Issue 3, pp.1767-1778

Belge Tipi:

Makale

Yayın Tarihi:

8/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000463798

Sıklık:

Üç Aylık

eISSN:

2536-4618

DOI:

https://doi.org/10.21597/jist.679021