THE EFFECT OF PREPARTUM ANTIOXIDANT ADMINISTRATIONS ON BLOOD BHBA CONCENTRATION IN COWS

Serdal KURT; Mert PEKCAN; Rıfat VURAL; Şükrü KÜPLÜLÜ

doi:https://doi.org/10.33483/jfpau.538179

Makale detayları

THE EFFECT OF PREPARTUM ANTIOXIDANT ADMINISTRATIONS ON BLOOD BHBA CONCENTRATION IN COWS

Yazarlar:

Serdal KURT | Mert PEKCAN | Rıfat VURAL | Şükrü KÜPLÜLÜ

Yayıncı:

Ankara University

Ana Başlıklar:

Farmakoloji ve terapötik

Dergi:

Journal of Faculty of Pharmacy of Ankara University 2019 Vol.43 Issue 2, pp.147-153

Belge Tipi:

Makale

Yayın Tarihi:

5/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000868110

Sıklık:

Üç Yıllık

eISSN:

2564-6524

pISSN:

1015-3918

DOI:

https://doi.org/10.33483/jfpau.538179

Anahtar kelimeler:

Özet:

 


Objective: The presented study was aimed that investigation effect of the prepartum antioxidant administration on blood Beta-hydroxybutyric acid (BHBA) concentrations at day 7th postpartum in Holstein dairy cows.


Antioxidants are defined as substances that delay or inhibits oxidative damage. Oxidantssuch as reactive oxygen species (ROS) are created as a consequence of adenosine triphosphate(ATP) production in mitochondria. Oxidants can cause tissue damage by damaging cells' macromolecules, such as DNA, proteins, and lipids. Lipids are the most sensitive macromolecule against oxidative damage. Oxidative stress can both disrupt the mechanism of insulin and induce more lipolysis. And so, ROS overproduction can enhance non‐esterified fatty acids (NEFA) and BHBA production.


Material and Method:Eighty multiparous Holstein breed pregnant dairy cows were used in this study. The cows were divided into two groups astreatment (G1; n=40) and control groups (G2; n=40). In the G1, solutions containing of vitamins (A, D, E) and trace elements (Cu, Zn, Se, Mn) were performed intramuscularly at 21±5 and 10±5 days before expected parturition (280 days). In the G2, it was performed the same amounts of saline injections as a placebo.


Result and Discussion: Blood BHBA levels were found that lower in the G1 group (0.73±0.20 mmol/L) compared to the G2 group (0.84±.29 mmol/L). In conclusion, it was determined that prepartum antioxidant administrations decrease blood BHBA concentration in the postpartum period in dairy cows.


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Makale detayları

THE EFFECT OF PREPARTUM ANTIOXIDANT ADMINISTRATIONS ON BLOOD BHBA CONCENTRATION IN COWS

Yazarlar:

Serdal KURT | Mert PEKCAN | Rıfat VURAL | Şükrü KÜPLÜLÜ

Yayıncı:

Ankara University

Ana Başlıklar:

Farmakoloji ve terapötik

Dergi:

Journal of Faculty of Pharmacy of Ankara University 2019 Vol.43 Issue 2, pp.147-153

Belge Tipi:

Makale

Yayın Tarihi:

5/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000868110

Sıklık:

Üç Yıllık

eISSN:

2564-6524

pISSN:

1015-3918

DOI:

https://doi.org/10.33483/jfpau.538179

antioksidan

BHBA

inek

oksidatif stres

Sayı

Makale detayları

THE EFFECT OF PREPARTUM ANTIOXIDANT ADMINISTRATIONS ON BLOOD BHBA CONCENTRATION IN COWS

Yazarlar: Serdal KURT | Mert PEKCAN | Rıfat VURAL | Şükrü KÜPLÜLÜ

Yayıncı: Ankara University

Ana Başlıklar: Farmakoloji ve terapötik

Dergi: Journal of Faculty of Pharmacy of Ankara University 2019 Vol.43 Issue 2, pp.147-153

Belge Tipi: Makale

Yayın Tarihi: 5/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000868110

Sıklık: Üç Yıllık

eISSN: 2564-6524

pISSN: 1015-3918

DOI: https://doi.org/10.33483/jfpau.538179

antioksidan

BHBA

inek

oksidatif stres

Sayı

Yazarlar:

Serdal KURT | Mert PEKCAN | Rıfat VURAL | Şükrü KÜPLÜLÜ

Yayıncı:

Ankara University

Ana Başlıklar:

Farmakoloji ve terapötik

Dergi:

Journal of Faculty of Pharmacy of Ankara University 2019 Vol.43 Issue 2, pp.147-153

Belge Tipi:

Makale

Yayın Tarihi:

5/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000868110

Sıklık:

Üç Yıllık

eISSN:

2564-6524

pISSN:

1015-3918

DOI:

https://doi.org/10.33483/jfpau.538179