The Value of The Halp Score in Predicting The Severity of  Coronary Artery Disease

Ömer Faruk Çiçek

Makale detayları

The Value of The Halp Score in Predicting The Severity of Coronary Artery Disease

Yazarlar:

Ömer Faruk Çiçek

Yayıncı:

Harran University

Ana Başlıklar:

Kardiyoloji

Dergi:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.22 Issue 3, pp.500-505

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

Türkçe

Document ID (Org No.):

2001352408

pISSN:

1304-9623

Anahtar kelimeler:

Özet:

 Background: Coronary artery disease CAD is the leading cause of death in both developed and developing countries. Atherosclerosis is a chronic inflammatory process. The HALP score, which includes measurements of hemoglobin, albumin, lymphocyte and platelet levels, has recently been recognized as a practical and easy-to-use tool to assess both systemic inflammation and nutritional status. In this study, we aimed to investigate the value of the HALP score in predicting the severity of CAD. Materials and Methods: The study included 450 patients who underwent coronary angiography CAG due to suspected CAD between June 2023 and February 2025 in our clinic retrospectively. Patients were catego-rized into normal, mild and severe coronary atherosclerosis using the Gensini scoring for the grading of CAD. The HALP score was calculated from the complete blood count and biochemical data obtained before CAG. Results: Patients were divided into two groups according to the median HALP cut-off value of 52.05. Patients with a cut-off value greater than 52.05 were defined as high HALP score and those with a cut-off value less than 52.05 were defined as low HALP score. The Gensini score was significantly higher in the group with a low HALP score compared to the group with a high HALP score p0.02. Additionally, the HALP score was found to decrease significantly as the severity of CAD increased according to the Gensini score p0.01. Correlation analysis revealed that the HALP score was negatively correlated with the Gensini score r -0.526, p0.001. Regression analysis revealed that the HALP score was an independent predictor of the Gensini score Ꞵ-0.37, t -2.12, p0.001. Conclusions: This study demonstrated that the HALP score may be a useful indicator for predicting the sever-ity of CAD.

 Background: Coronary artery disease CAD is the leading cause of death in both developed and developing countries. Atherosclerosis is a chronic inflammatory process. The HALP score, which includes measurements of hemoglobin, albumin, lymphocyte and platelet levels, has recently been recognized as a practical and easy-to-use tool to assess both systemic inflammation and nutritional status. In this study, we aimed to investigate the value of the HALP score in predicting the severity of CAD. Materials and Methods: The study included 450 patients who underwent coronary angiography CAG due to suspected CAD between June 2023 and February 2025 in our clinic retrospectively. Patients were catego-rized into normal, mild and severe coronary atherosclerosis using the Gensini scoring for the grading of CAD. The HALP score was calculated from the complete blood count and biochemical data obtained before CAG. Results: Patients were divided into two groups according to the median HALP cut-off value of 52.05. Patients with a cut-off value greater than 52.05 were defined as high HALP score and those with a cut-off value less than 52.05 were defined as low HALP score. The Gensini score was significantly higher in the group with a low HALP score compared to the group with a high HALP score p0.02. Additionally, the HALP score was found to decrease significantly as the severity of CAD increased according to the Gensini score p0.01. Correlation analysis revealed that the HALP score was negatively correlated with the Gensini score r -0.526, p0.001. Regression analysis revealed that the HALP score was an independent predictor of the Gensini score Ꞵ-0.37, t -2.12, p0.001. Conclusions: This study demonstrated that the HALP score may be a useful indicator for predicting the sever-ity of CAD.

 Background: Coronary artery disease CAD is the leading cause of death in both developed and developing countries. Atherosclerosis is a chronic inflammatory process. The HALP score, which includes measurements of hemoglobin, albumin, lymphocyte and platelet levels, has recently been recognized as a practical and easy-to-use tool to assess both systemic inflammation and nutritional status. In this study, we aimed to investigate the value of the HALP score in predicting the severity of CAD. Materials and Methods: The study included 450 patients who underwent coronary angiography CAG due to suspected CAD between June 2023 and February 2025 in our clinic retrospectively. Patients were catego-rized into normal, mild and severe coronary atherosclerosis using the Gensini scoring for the grading of CAD. The HALP score was calculated from the complete blood count and biochemical data obtained before CAG. Results: Patients were divided into two groups according to the median HALP cut-off value of 52.05. Patients with a cut-off value greater than 52.05 were defined as high HALP score and those with a cut-off value less than 52.05 were defined as low HALP score. The Gensini score was significantly higher in the group with a low HALP score compared to the group with a high HALP score p0.02. Additionally, the HALP score was found to decrease significantly as the severity of CAD increased according to the Gensini score p0.01. Correlation analysis revealed that the HALP score was negatively correlated with the Gensini score r -0.526, p0.001. Regression analysis revealed that the HALP score was an independent predictor of the Gensini score Ꞵ-0.37, t -2.12, p0.001. Conclusions: This study demonstrated that the HALP score may be a useful indicator for predicting the sever-ity of CAD.

 Amaç: Koroner arter hastalığı KAH, hem gelişmiş hem de gelişmekte olan ülkelerde önde gelen ölüm nedenidir. Ateroskleroz kronik bir inflamatuvar süreçtir. Hemoglobin, albümin, lenfosit ve trombosit düzeylerinin ölçümlerini içeren HALP skoru, son zamanlarda hem sistemik inflamasyonu hem de beslenme durumunu değerlendirmek için pratik ve kullanımı kolay bir araç olarak kabul edilmiştir. Bu çalışmada, HALP skorunun KAHın şiddetini öngörmedeki değerini araştırmayı amaçladık. Materyal ve metod: Çalışmaya, Haziran 2023 ile Şubat 2025 arasında kliniğimizde şüpheli KAH nedeniyle koroner anjiyografi KAG uygulanan 450 ardışık hasta, retrospektif olarak dahil edildi. Hastalar, KAH ciddiyetinin derecelendirilmesi için Gensini skorlaması kullanılarak normal, hafif ve şiddetli koroner ateroskleroz olarak kategorize edildi. HALP skoru, KAGden önce elde edilen tam kan sayımı ve biyokimyasal verilerden hesaplandı. Bulgular: Hastalar, medyan HALP kesme değeri olan 52.05e göre iki gruba ayrıldı. Kesme değeri 52.05ten büyük olan hastalar yüksek HALP skoru, kesme değeri 52.05ten küçük olan hastalar ise düşük HALP skoru olarak tanımlandı. HALP skoru düşük olan grupta HALP skoru yüksek olan gruba göre Gensini skoru anlamlı olarak daha yüksek idi p0.02. Ek olarak, Gensini skoruna göre KAH ciddiyeti arrtıkça HALP skorunun da anlamlı olarak azaldığı tespit edildi p0.01. Yapılan korelasyon analizinde HALP skorunun Gensini skoru ile negatif bir şekilde korele olduğu tespit edildi r -0.526, p 0.001. Yapılan regresyon analizinde HALP skoru, Gensini skorunun bağımsız bir öngördürücüsü olarak tespit edildi β  0.37, p  0.001. Sonuç: Bu çalışma, HALP skorunun KAHın şiddetini öngörmede yararlı bir gösterge olabileceğini göstermiştir.

Makale detayları

The Value of The Halp Score in Predicting The Severity of Coronary Artery Disease

Yazarlar:

Ömer Faruk Çiçek

Yayıncı:

Harran University

Ana Başlıklar:

Kardiyoloji

Dergi:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.22 Issue 3, pp.500-505

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

Türkçe

Document ID (Org No.):

2001352408

pISSN:

1304-9623

HALP score

coronary angiography

coronary artery diseaseHALP skoru

koroner anjiyografi

koroner arter hastalığı

Sayı

Makale detayları

The Value of The Halp Score in Predicting The Severity of Coronary Artery Disease

Yazarlar: Ömer Faruk Çiçek

Yayıncı: Harran University

Ana Başlıklar: Kardiyoloji

Dergi: Harran Üniversitesi Tıp Fakültesi Dergisi Vol.22 Issue 3, pp.500-505

Belge Tipi: Makale

Yayın Tarihi: 9/2025

Belge Dili: Türkçe

Document ID (Org No.): 2001352408

pISSN: 1304-9623

HALP score

coronary angiography

coronary artery diseaseHALP skoru

koroner anjiyografi

koroner arter hastalığı

Sayı

Yazarlar:

Ömer Faruk Çiçek

Yayıncı:

Harran University

Ana Başlıklar:

Kardiyoloji

Dergi:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.22 Issue 3, pp.500-505

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

Türkçe

Document ID (Org No.):

2001352408

pISSN:

1304-9623