HEPATOPROTECTIVE EFFECT OF TOFU PROCESSED FROM GERMINATED SOYBEAN ON CARBON TETRACHLORIDE INDUCED CHRONIC LIVER INJURY IN MICE

Duong Thi Phuong LİEN; Cao Thi Kim HOANG; Nguyen Thi HANH; Duong Xuan CHU; Phan Thi Bich TRAM; Ha Thanh TOAN

doi:https://doi.org/10.3153/JFHS17001

Makale detayları

HEPATOPROTECTIVE EFFECT OF TOFU PROCESSED FROM GERMINATED SOYBEAN ON CARBON TETRACHLORIDE INDUCED CHRONIC LIVER INJURY IN MICE

Yazarlar:

Duong Thi Phuong LİEN | Cao Thi Kim HOANG | Nguyen Thi HANH | Duong Xuan CHU | Phan Thi Bich TRAM | Ha Thanh TOAN

Dergi:

Food and Health 2017 Vol.3 Issue 1, pp.1-11

Belge Tipi:

Makale

Yayın Tarihi:

12/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000420088

DOI:

https://doi.org/10.3153/JFHS17001

Özet:

 


The hepatoprotective activities of silk
tofu made from germinated and non germinated soybeans at different doses of
feeding against CCl4 induced hepatic cell toxicity in mice was
investigated in this study. The heptatoprotective activity was analyzed by
assessing the ratio of liver weight to body weight (L/B), the levels of serum
alanine aminotransferase (ALT), total cholesterols (TC), the hepatic
malondehydyde (MDA), protein carbonyl (PC) and vitamin C levels as well as the
histopathological analysis of liver tissue. All types of silk tofu
significantly reduced the L/B value; ALT activity, total cholesterol, hepatic
MDA and PC levels, beside, liver vitamin C content increased compared to CCl4
intoxicated mice. Silk tofu made from germinated soybeans expressed higher
hepatoprotective activity as compared to silk tofu made from non germinated
soybeans. Mice fed with silk tofu made from germinated soybeans at the dose of
0.4 g/g body weight/day displayed all biochemical parameters as well as the
liver tissue histopathological analysis that were similar to that of normal
mice and silymarin treated mice. It was suggested that tofu specially made from
germinated soybeans expressed great hepatoprotective effect.


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Makale detayları

HEPATOPROTECTIVE EFFECT OF TOFU PROCESSED FROM GERMINATED SOYBEAN ON CARBON TETRACHLORIDE INDUCED CHRONIC LIVER INJURY IN MICE

Yazarlar: Duong Thi Phuong LİEN | Cao Thi Kim HOANG | Nguyen Thi HANH | Duong Xuan CHU | Phan Thi Bich TRAM | Ha Thanh TOAN

Dergi: Food and Health 2017 Vol.3 Issue 1, pp.1-11

Belge Tipi: Makale

Yayın Tarihi: 12/2016

Belge Dili: Türkçe

Document ID (Org No.): 2000420088

DOI: https://doi.org/10.3153/JFHS17001

Sayı

Yazarlar:

Duong Thi Phuong LİEN | Cao Thi Kim HOANG | Nguyen Thi HANH | Duong Xuan CHU | Phan Thi Bich TRAM | Ha Thanh TOAN

Dergi:

Food and Health 2017 Vol.3 Issue 1, pp.1-11

Belge Tipi:

Makale

Yayın Tarihi:

12/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000420088

DOI:

https://doi.org/10.3153/JFHS17001