Gram Negative Bacteria Isolated from Blood Cultures and Their Antibiotic Susceptibility

Mehtap Hülya Aslan; Metekoray Vural

Makale detayları

Gram Negative Bacteria Isolated from Blood Cultures and Their Antibiotic Susceptibility

Yazarlar:

Mehtap Hülya Aslan | Metekoray Vural

Yayıncı:

Ataturk University

Ana Başlıklar:

Genel Cerrahi

Dergi:

Trends in Surgical Sciences Vol.4 Issue 1, pp.11-17

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344794

pISSN:

3062-3308

Anahtar kelimeler:

Özet:

 Objective: Blood stream infections cause serious mortality and morbidity in patients, especially in intensive care units of hospitals. Detection of the causative microorganism as soon as possible and planning appropriate antibiotic treatment reduce mortality rates. The aim of this study is to determinethe gram negative bacteria grown in blood culture samples brought to the laboratory from various services, primarily surgical intensive care units of our hospital, and the antibiotics effective on them, and to contribute to clinicians initiating empirical treatment. Methods: Gram negative bacteria grown in blood culture samples brought to the laboratory from various services, primarily surgical intensive care units of our hospital, and the antibiotics effective on them were investigated retrospectively. Results: Gram negative bacteria were grown in 332 23 of 1,270 samples with blood culture growth. The growth rate in blood culture samples sent from intensive care units was in the first place with 165 49. Of the isolated gram negative bacteria, 113 34 were Acinetobacter Baumannii, 58 17 were Escherichia coli, 51 15 were Klebsiella pneumoniae, 42 12 were Pseudomonas aeruginosa, 16 4 were Brucella spp., 14 4 were Enterobacterspp., 12 3 were Serratia marcescens, 12 3 were Burkholderia cepacia, 10 3 were Stenotrophomonas maltophilia, and 4 1 were Citrobacter spp. Extended spectrum beta-lactamase ESBL was detected in 37 80 of K. Pneumonai strains and 28 48 of E. Coli strains. Conclusion: In order to reduce the mortality and morbidi ty rates of patients hospitalized in intensive care units, laboratories performing blood culture should conduc tmore comprehensive studies to identify the agents they isolate and the appropriate antibiotics to guide clinicians in initiating treatment.

 Objective: Blood stream infections cause serious mortality and morbidity in patients, especially in intensive care units of hospitals. Detection of the causative microorganism as soon as possible and planning appropriate antibiotic treatment reduce mortality rates. The aim of this study is to determinethe gram negative bacteria grown in blood culture samples brought to the laboratory from various services, primarily surgical intensive care units of our hospital, and the antibiotics effective on them, and to contribute to clinicians initiating empirical treatment. Methods: Gram negative bacteria grown in blood culture samples brought to the laboratory from various services, primarily surgical intensive care units of our hospital, and the antibiotics effective on them were investigated retrospectively. Results: Gram negative bacteria were grown in 332 23 of 1,270 samples with blood culture growth. The growth rate in blood culture samples sent from intensive care units was in the first place with 165 49. Of the isolated gram negative bacteria, 113 34 were Acinetobacter Baumannii, 58 17 were Escherichia coli, 51 15 were Klebsiella pneumoniae, 42 12 were Pseudomonas aeruginosa, 16 4 were Brucella spp., 14 4 were Enterobacterspp., 12 3 were Serratia marcescens, 12 3 were Burkholderia cepacia, 10 3 were Stenotrophomonas maltophilia, and 4 1 were Citrobacter spp. Extended spectrum beta-lactamase ESBL was detected in 37 80 of K. Pneumonai strains and 28 48 of E. Coli strains. Conclusion: In order to reduce the mortality and morbidi ty rates of patients hospitalized in intensive care units, laboratories performing blood culture should conduc tmore comprehensive studies to identify the agents they isolate and the appropriate antibiotics to guide clinicians in initiating treatment.

 Objective: Blood stream infections cause serious mortality and morbidity in patients, especially in intensive care units of hospitals. Detection of the causative microorganism as soon as possible and planning appropriate antibiotic treatment reduce mortality rates. The aim of this study is to determinethe gram negative bacteria grown in blood culture samples brought to the laboratory from various services, primarily surgical intensive care units of our hospital, and the antibiotics effective on them, and to contribute to clinicians initiating empirical treatment. Methods: Gram negative bacteria grown in blood culture samples brought to the laboratory from various services, primarily surgical intensive care units of our hospital, and the antibiotics effective on them were investigated retrospectively. Results: Gram negative bacteria were grown in 332 23 of 1,270 samples with blood culture growth. The growth rate in blood culture samples sent from intensive care units was in the first place with 165 49. Of the isolated gram negative bacteria, 113 34 were Acinetobacter Baumannii, 58 17 were Escherichia coli, 51 15 were Klebsiella pneumoniae, 42 12 were Pseudomonas aeruginosa, 16 4 were Brucella spp., 14 4 were Enterobacterspp., 12 3 were Serratia marcescens, 12 3 were Burkholderia cepacia, 10 3 were Stenotrophomonas maltophilia, and 4 1 were Citrobacter spp. Extended spectrum beta-lactamase ESBL was detected in 37 80 of K. Pneumonai strains and 28 48 of E. Coli strains. Conclusion: In order to reduce the mortality and morbidi ty rates of patients hospitalized in intensive care units, laboratories performing blood culture should conduc tmore comprehensive studies to identify the agents they isolate and the appropriate antibiotics to guide clinicians in initiating treatment.

 Amaç: Kan dolaşımı enfeksiyonları, hastanelerin özellikle yoğun bakım servislerinde yatan hastalarda ciddi mortalite ve morbiditeye sebep olur. Etken mikroorganizmanın en kısa sürede tespit edilmesi ve uygun antibiyotik tedavisinin planlanması mortalite oranlarını düşürmektedir. Bu çalışmanın amacı, hastanemiz cerrahi yoğun bakım servisleri başta olmak üzere çeşitli servislerden laboratuvara gelen kan kültür örneklerinde üreyen gram negatif bakterilerle bunlara etkili antibiyotikleri tespit ederek klinisyenlerin ampirik tedavi protokollerine katkı saklamaktır. Yöntemler: Hastanemiz cerrahi yoğun bakım servisleri başta olmak üzere çeşitli servislerden laboratuvara gelen kan kültür örneklerinde üreyen gram negatif bakterilerle bunlara etkili antibiyotikler retrospektif olarak araştırıldı. Bulgular: Kan kültüründe üreme olan 1.270 örneğin 332sinde 23 gram negatif bakteri üremişti. Yoğun bakım servislerinden gönderilen kan kültür örneklerinde üreme oranı 165 49 ile birinci sırada idi. Üreyen gram negatif bakterilerin 113ü 34 Acinetobacter baumannii, 58i 17 Escherichia coli, 51i 15 Klebsiella pneumoniae, 42si 12 Pseudomonas aeruginosa, 16sı 4 Brusella spp, 14ü 4 Enterobacter spp., 12si 3 Serratia marcescens, 12si 3 Burkholderia cepacia, 10u 3 Stenotrophomonas maltophilia, 4ü 1 Citrobacter spp. idi. K.pneumonaie suşunun 37sinde 80, E.coli suşunun 28inde 48 genişlemiş spektrumlu beta-laktamaz GSBL saptandı. Sonuç: Yoğun bakım servislerinde yatan hastaların mortalite ve morbitide oranlarını düşürmek amacıyla kan kültürü çalışan laboratuvarlar izole ettikleri etkenleri ve bunlara uygun antibiyotikleri tespit ederek klinisyenlerin tedaviye başlamalarında yardımcı olacak daha kapsamlı çalışmalar yapmalıdır.

Makale detayları

Gram Negative Bacteria Isolated from Blood Cultures and Their Antibiotic Susceptibility

Yazarlar:

Mehtap Hülya Aslan | Metekoray Vural

Yayıncı:

Ataturk University

Ana Başlıklar:

Genel Cerrahi

Dergi:

Trends in Surgical Sciences Vol.4 Issue 1, pp.11-17

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344794

pISSN:

3062-3308

Gram negative bacteria

blood culture

antibiotic susceptibility

Sayı

Makale detayları

Gram Negative Bacteria Isolated from Blood Cultures and Their Antibiotic Susceptibility

Yazarlar: Mehtap Hülya Aslan | Metekoray Vural

Yayıncı: Ataturk University

Ana Başlıklar: Genel Cerrahi

Dergi: Trends in Surgical Sciences Vol.4 Issue 1, pp.11-17

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001344794

pISSN: 3062-3308

Gram negative bacteria

blood culture

antibiotic susceptibility

Sayı

Yazarlar:

Mehtap Hülya Aslan | Metekoray Vural

Yayıncı:

Ataturk University

Ana Başlıklar:

Genel Cerrahi

Dergi:

Trends in Surgical Sciences Vol.4 Issue 1, pp.11-17

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344794

pISSN:

3062-3308