Evaluation of pulmonary artery stiffness in patients with systemic sclerosis

Dursun Akaslan; Murat Demirci

Makale detayları

Evaluation of pulmonary artery stiffness in patients with systemic sclerosis

Yazarlar:

Dursun Akaslan | Murat Demirci

Yayıncı:

Marmara University

Ana Başlıklar:

Surgery (Other)

Dergi:

Marmara Medical Journal Vol.37 Issue 1, pp.11-17

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001302654

pISSN:

1019-1941

Anahtar kelimeler:

Özet:

 Objective: The study aims to investigate the use of pulmonary artery stiffness PAS parameter in early diagnosis of systemic sclerosis SSc and pulmonary hypertension in SSc patients. Patients and Methods: The study involved 102 SSc patients and 45 control group patients, who underwent transthoracic echocardiographic evaluations. Results: Pulmonary artery stiffness was measured as 25.77.6 Hzmsn in the SSc cases and 13.7 1.6 Hzmsn in the healthy subjects P 0.001. TAPSEsPAP ratio, which we used as an indicator of RV-PA coupling, was calculated as 0.650.28 in SSc cases and 1.120.33 in the control group P0.001. When we evaluated PAS values of subgroups PAS was significantly higher in SScPH- patients without pulmonary hypertension than control subjects respectively; 21.67  3.9; 13.7  1.6, P0.001. The relationship of PAS with the parameters in which pulmonary hypertension and right ventricular functions were evaluated, there was a positive correlation with sPAP r:  0.396, P 0.001, while a negative correlation was observed with TAPSEsPAP r: 0.456, P0.001. Conclusion: We observed higher PAS values in SScPH- patients compared to the control group and found a positive correlation between the increase in PAS and sPAP and a negative correlation between them and TAPSEsPAP.

 Objective: The study aims to investigate the use of pulmonary artery stiffness PAS parameter in early diagnosis of systemic sclerosis SSc and pulmonary hypertension in SSc patients. Patients and Methods: The study involved 102 SSc patients and 45 control group patients, who underwent transthoracic echocardiographic evaluations. Results: Pulmonary artery stiffness was measured as 25.77.6 Hzmsn in the SSc cases and 13.7 1.6 Hzmsn in the healthy subjects P 0.001. TAPSEsPAP ratio, which we used as an indicator of RV-PA coupling, was calculated as 0.650.28 in SSc cases and 1.120.33 in the control group P0.001. When we evaluated PAS values of subgroups PAS was significantly higher in SScPH- patients without pulmonary hypertension than control subjects respectively; 21.67  3.9; 13.7  1.6, P0.001. The relationship of PAS with the parameters in which pulmonary hypertension and right ventricular functions were evaluated, there was a positive correlation with sPAP r:  0.396, P 0.001, while a negative correlation was observed with TAPSEsPAP r: 0.456, P0.001. Conclusion: We observed higher PAS values in SScPH- patients compared to the control group and found a positive correlation between the increase in PAS and sPAP and a negative correlation between them and TAPSEsPAP.

 Objective: The study aims to investigate the use of pulmonary artery stiffness PAS parameter in early diagnosis of systemic sclerosis SSc and pulmonary hypertension in SSc patients. Patients and Methods: The study involved 102 SSc patients and 45 control group patients, who underwent transthoracic echocardiographic evaluations. Results: Pulmonary artery stiffness was measured as 25.77.6 Hzmsn in the SSc cases and 13.7 1.6 Hzmsn in the healthy subjects P 0.001. TAPSEsPAP ratio, which we used as an indicator of RV-PA coupling, was calculated as 0.650.28 in SSc cases and 1.120.33 in the control group P0.001. When we evaluated PAS values of subgroups PAS was significantly higher in SScPH- patients without pulmonary hypertension than control subjects respectively; 21.67  3.9; 13.7  1.6, P0.001. The relationship of PAS with the parameters in which pulmonary hypertension and right ventricular functions were evaluated, there was a positive correlation with sPAP r:  0.396, P 0.001, while a negative correlation was observed with TAPSEsPAP r: 0.456, P0.001. Conclusion: We observed higher PAS values in SScPH- patients compared to the control group and found a positive correlation between the increase in PAS and sPAP and a negative correlation between them and TAPSEsPAP.

 Objective: The study aims to investigate the use of pulmonary artery stiffness PAS parameter in early diagnosis of systemic sclerosis SSc and pulmonary hypertension in SSc patients. Patients and Methods: The study involved 102 SSc patients and 45 control group patients, who underwent transthoracic echocardiographic evaluations. Results: Pulmonary artery stiffness was measured as 25.77.6 Hzmsn in the SSc cases and 13.7 1.6 Hzmsn in the healthy subjects P 0.001. TAPSEsPAP ratio, which we used as an indicator of RV-PA coupling, was calculated as 0.650.28 in SSc cases and 1.120.33 in the control group P0.001. When we evaluated PAS values of subgroups PAS was significantly higher in SScPH- patients without pulmonary hypertension than control subjects respectively; 21.67  3.9; 13.7  1.6, P0.001. The relationship of PAS with the parameters in which pulmonary hypertension and right ventricular functions were evaluated, there was a positive correlation with sPAP r:  0.396, P 0.001, while a negative correlation was observed with TAPSEsPAP r: 0.456, P0.001. Conclusion: We observed higher PAS values in SScPH- patients compared to the control group and found a positive correlation between the increase in PAS and sPAP and a negative correlation between them and TAPSEsPAP.

Makale detayları

Evaluation of pulmonary artery stiffness in patients with systemic sclerosis

Yazarlar:

Dursun Akaslan | Murat Demirci

Yayıncı:

Marmara University

Ana Başlıklar:

Surgery (Other)

Dergi:

Marmara Medical Journal Vol.37 Issue 1, pp.11-17

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001302654

pISSN:

1019-1941

Pulmonary hypertension

Systemic sclerosis

Transthoracic Echocardiography

Pulmonary arterial stiffness

TAPSE/sPAP ratio

Sayı

Makale detayları

Evaluation of pulmonary artery stiffness in patients with systemic sclerosis

Yazarlar: Dursun Akaslan | Murat Demirci

Yayıncı: Marmara University

Ana Başlıklar: Surgery (Other)

Dergi: Marmara Medical Journal Vol.37 Issue 1, pp.11-17

Belge Tipi: Makale

Yayın Tarihi: 1/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001302654

pISSN: 1019-1941

Pulmonary hypertension

Systemic sclerosis

Transthoracic Echocardiography

Pulmonary arterial stiffness

TAPSE/sPAP ratio

Sayı

Yazarlar:

Dursun Akaslan | Murat Demirci

Yayıncı:

Marmara University

Ana Başlıklar:

Surgery (Other)

Dergi:

Marmara Medical Journal Vol.37 Issue 1, pp.11-17

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001302654

pISSN:

1019-1941