Sequence characterization of full-length S

Yeganeh YOUSEFI; Mohammad Reza BASSAMI; Gholam Ali KALIDARI; Mohammad Mehdi Ghahramani SENO

Makale detayları

Sequence characterization of full-length S

Yazarlar:

Yeganeh YOUSEFI | Mohammad Reza BASSAMI | Gholam Ali KALIDARI | Mohammad Mehdi Ghahramani SENO

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2019 Vol.43 Issue 2, pp.235-243

Belge Tipi:

Makale

Yayın Tarihi:

3/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000764353

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Özet:

 

Infectious bronchitis virus (IBV) causes heavy economic losses in chicken farms worldwide. Like many other viral diseases, vaccination is the gold standard approach in controlling and preventing the spread of IBV. However, IBV is continuously evolving and new strains of this virus emerge that, due to variable antigenic cross-reactivity, may reduce or nullify the protective effect of vaccination programs. Therefore, advance knowledge of the IBV strain(s) circulating in a region will be very useful in deciding which commercial vaccine(s) would be most effective. In this line, we analyzed the nucleotide sequence of the full-length 111_{1} gene of IBV viruses isolated from broiler and layer flocks in the northeast of Iran. Three to five birds from each of 19 suspected flocks were used to collect tissue samples and six individual virus isolates were obtained from these tissue samples. Homology analyses using S1 gene nucleotide sequence data revealed that three out of our six isolates were closest to QX-like IBV strains and the rest had the best homology with Variant 2-like (IS/1494) strains. Phylogenetic analyses grouped our isolates into two clusters, one that included Chinese QX isolates and another formed of Variant 2-like isolates mainly reported in Middle Eastern countries. Our study shows that QX and Variant 2-like strains are major IBV viruses circulating in broiler and layer flocks of the northeast of Iran, an important fact that needs to be considered for vaccination programs.

Makale detayları

Sequence characterization of full-length S

Yazarlar: Yeganeh YOUSEFI | Mohammad Reza BASSAMI | Gholam Ali KALIDARI | Mohammad Mehdi Ghahramani SENO

Yayıncı: TUBITAK

Dergi: Turkish Journal of Veterinary and Animal Sciences 2019 Vol.43 Issue 2, pp.235-243

Belge Tipi: Makale

Yayın Tarihi: 3/2019

Belge Dili: Türkçe

Document ID (Org No.): 2000764353

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

Sayı

Yazarlar:

Yeganeh YOUSEFI | Mohammad Reza BASSAMI | Gholam Ali KALIDARI | Mohammad Mehdi Ghahramani SENO

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2019 Vol.43 Issue 2, pp.235-243

Belge Tipi:

Makale

Yayın Tarihi:

3/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000764353

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128