Determination of Serum Biochemical Profile and Oxidant-Antioxidant Activities in Damascus Goats at Different Ages

Hakan Tekeli; Süleyman Şensoy; Gamze Sevri Ekren Aşıcı

Makale detayları

Determination of Serum Biochemical Profile and Oxidant-Antioxidant Activities in Damascus Goats at Different Ages

Yazarlar:

Hakan Tekeli | Süleyman Şensoy | Gamze Sevri Ekren Aşıcı

Yayıncı:

Ataturk University

Ana Başlıklar:

Veteriner Biyokimya | Veteriner Farmakoloji

Dergi:

Veterinary Sciences and Practices Vol.19 Issue 1, pp.1-8

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001316088

pISSN:

2822-3608

Anahtar kelimeler:

Özet:

 This study aimed to research changes in biochemical profile and oxidant-antioxidant activities of Damascus goats of different ages. The 45 non-gravid Damascus goats of different ages were included in the research. They were divided into three groups of 15 goats according to age: goat kids  -  6-months age, young goats 2-3-year age and old goats 5-8-year age. Biochemical parameters and oxidant-antioxidant activities were determined in serum samples using commercial kits and colorimetric methods. The lowest serum urea, blood urea nitrogen, aspartate aminotransferase, total protein, albumin, globulin and magnesium levels were observed in goat kids P  .05. Concentrations of glucose, inorganic phosphorus, non-esterified fatty acids, albuminglobulin and alanine aminotransferase decreased with age in the goats P  .05. Serum total oxidant capacity, total antioxidants capacity and oxidative stress index levels were increased in goat kids compared to old goats P  .05. Furthermore the highest serum glutathione and glutathione preoxidase activities were observed in young goats P  .05. An increase was determined in concentrations of serum β-carotene and bilirubin in old goats compared to goat kids P  .05. In contrast, serum catalase activity, arylesterase, ceruloplasmin and uric acid values did not differ between the groups. The results obtained on the biochemical profiles and oxidant-antioxidant activities of Damascus goats will contribute to monitoring this breeds age-related health and nutritional status and establishing reference values.

 This study aimed to research changes in biochemical profile and oxidant-antioxidant activities of Damascus goats of different ages. The 45 non-gravid Damascus goats of different ages were included in the research. They were divided into three groups of 15 goats according to age: goat kids  -  6-months age, young goats 2-3-year age and old goats 5-8-year age. Biochemical parameters and oxidant-antioxidant activities were determined in serum samples using commercial kits and colorimetric methods. The lowest serum urea, blood urea nitrogen, aspartate aminotransferase, total protein, albumin, globulin and magnesium levels were observed in goat kids P  .05. Concentrations of glucose, inorganic phosphorus, non-esterified fatty acids, albuminglobulin and alanine aminotransferase decreased with age in the goats P  .05. Serum total oxidant capacity, total antioxidants capacity and oxidative stress index levels were increased in goat kids compared to old goats P  .05. Furthermore the highest serum glutathione and glutathione preoxidase activities were observed in young goats P  .05. An increase was determined in concentrations of serum β-carotene and bilirubin in old goats compared to goat kids P  .05. In contrast, serum catalase activity, arylesterase, ceruloplasmin and uric acid values did not differ between the groups. The results obtained on the biochemical profiles and oxidant-antioxidant activities of Damascus goats will contribute to monitoring this breeds age-related health and nutritional status and establishing reference values.

 This study aimed to research changes in biochemical profile and oxidant-antioxidant activities of Damascus goats of different ages. The 45 non-gravid Damascus goats of different ages were included in the research. They were divided into three groups of 15 goats according to age: goat kids  -  6-months age, young goats 2-3-year age and old goats 5-8-year age. Biochemical parameters and oxidant-antioxidant activities were determined in serum samples using commercial kits and colorimetric methods. The lowest serum urea, blood urea nitrogen, aspartate aminotransferase, total protein, albumin, globulin and magnesium levels were observed in goat kids P  .05. Concentrations of glucose, inorganic phosphorus, non-esterified fatty acids, albuminglobulin and alanine aminotransferase decreased with age in the goats P  .05. Serum total oxidant capacity, total antioxidants capacity and oxidative stress index levels were increased in goat kids compared to old goats P  .05. Furthermore the highest serum glutathione and glutathione preoxidase activities were observed in young goats P  .05. An increase was determined in concentrations of serum β-carotene and bilirubin in old goats compared to goat kids P  .05. In contrast, serum catalase activity, arylesterase, ceruloplasmin and uric acid values did not differ between the groups. The results obtained on the biochemical profiles and oxidant-antioxidant activities of Damascus goats will contribute to monitoring this breeds age-related health and nutritional status and establishing reference values.

 Bu çalışmada, farklı yaşlardaki Şam keçilerinin biyokimyasal profillerindeki değişikliklerin ve oksidan-antioksidan aktivitelerin araştırılması amaçlandı. Araştırmaya 45 adet gebe olmayan farklı yaşlardaki Şam keçisi dahil edildi. Keçiler yaşlarına göre üç gruba ayrıldı: keçi yavruları  -  6-aylık, genç keçiler 2-3-yaş ve yaşlı keçiler 5-8-yaş. Serum örneklerinde biyokimyasal parametreler ve oksidan-antioksidan aktiviteler ticari kitler ve kolorimetrik yöntemler kullanılarak belirlendi. En düşük serum üre, kan üre azotu, aspartat aminotransferaz, total protein, albumin, globulin ve magnezyum seviyeleri keçi yavrularında gözlemlendi P  .05. Glukoz, inorganik fosfor, non-esterifiye yağ asitleri, albuminglobulin ve alanin aminotransferaz konsantrasyonları keçilerde yaşla birlikte azaldı P  .05. Serum total oksidan kapasitesi, total antioksidan kapasitesi ve oksidatif stres indeksi düzeyleri keçi yavrularında yaşlı keçilere göre yüksekti P  .05. En yüksek serum glutatyon ve glutatyon peroksidaz aktiviteleri genç keçilerde gözlemlendi P  .05. Keçi yavrularına kıyasla yaşlı keçilerde serum β-karoten ve bilirubin konsantrasyonlarında artış tespit edildi P  .05. Buna karşın serum katalaz aktivitesi, arilesteraz, seruloplazmin ve ürik asit değerleri gruplar arasında farklılık göstermedi. Elde edilen sonuçlar, bu ırkın yaşla ilişkili sağlık ve beslenme durumunun izlenmesine ve referans değerlerin belirlenmesine katkı sağlayacaktır.

Makale detayları

Determination of Serum Biochemical Profile and Oxidant-Antioxidant Activities in Damascus Goats at Different Ages

Yazarlar:

Hakan Tekeli | Süleyman Şensoy | Gamze Sevri Ekren Aşıcı

Yayıncı:

Ataturk University

Ana Başlıklar:

Veteriner Biyokimya | Veteriner Farmakoloji

Dergi:

Veterinary Sciences and Practices Vol.19 Issue 1, pp.1-8

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001316088

pISSN:

2822-3608

Antioxidants

age

blood parameters

damascus goatsAntioksidanlar

kan parametreleri

Şam keçisi

yaş

Sayı

Makale detayları

Yazarlar: Hakan Tekeli | Süleyman Şensoy | Gamze Sevri Ekren Aşıcı

Yayıncı: Ataturk University

Ana Başlıklar: Veteriner Biyokimya | Veteriner Farmakoloji

Dergi: Veterinary Sciences and Practices Vol.19 Issue 1, pp.1-8

Belge Tipi: Makale

Yayın Tarihi: 4/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001316088

pISSN: 2822-3608

Sayı

Yazarlar:

Hakan Tekeli | Süleyman Şensoy | Gamze Sevri Ekren Aşıcı

Yayıncı:

Ataturk University

Ana Başlıklar:

Veteriner Biyokimya | Veteriner Farmakoloji

Dergi:

Veterinary Sciences and Practices Vol.19 Issue 1, pp.1-8

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001316088

pISSN:

2822-3608