Biochemical Bone Markers in Prostate Cancer Patients with Local and Advanced Bone Metastates

Hülya AKSOY

Makale detayları

Biochemical Bone Markers in Prostate Cancer Patients with Local and Advanced Bone Metastates

Yazarlar:

Hülya AKSOY

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2001 Vol.31 Issue 1, pp.65-68

Belge Tipi:

Makale

Yayın Tarihi:

12/2000

Belge Dili:

Türkçe

Document ID (Org No.):

2000757434

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

In the present study involving patients with bone metastases arising from prostate cancer, we measured urinary deoxypyridinoline (DPD) as a marker of collagen breakdown activity, serum total and bone-specific alkaline phosphatase activities and serum prostate specific antigen (PSA). This study included 20 patients with benign prostate hyperplasia (BPH) and 23 patients with carcinoma, 11 of had with bone metastases. DPD excretion in urine was significantly greater in prostate cancer patients with bone metastasis than in those with localised prostate cancer or BPH (p0.05). The serum markers of bone formation [total alkaline phosphatase (T-ALP) and bone ALP (B-ALP)] displayed higher mean concentrations in the group with positive bone metastases than in the group with local disease (p.

 

In the present study involving patients with bone metastases arising from prostate cancer, we measured urinary deoxypyridinoline (DPD) as a marker of collagen breakdown activity, serum total and bone-specific alkaline phosphatase activities and serum prostate specific antigen (PSA). This study included 20 patients with benign prostate hyperplasia (BPH) and 23 patients with carcinoma, 11 of had with bone metastases. DPD excretion in urine was significantly greater in prostate cancer patients with bone metastasis than in those with localised prostate cancer or BPH (p0.05). The serum markers of bone formation [total alkaline phosphatase (T-ALP) and bone ALP (B-ALP)] displayed higher mean concentrations in the group with positive bone metastases than in the group with local disease (p.

Makale detayları

Biochemical Bone Markers in Prostate Cancer Patients with Local and Advanced Bone Metastates

Yazarlar:

Hülya AKSOY

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2001 Vol.31 Issue 1, pp.65-68

Belge Tipi:

Makale

Yayın Tarihi:

12/2000

Belge Dili:

Türkçe

Document ID (Org No.):

2000757434

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Prostate cancer

Deoxypyridinoline

Bone markers

Sayı

Makale detayları

Biochemical Bone Markers in Prostate Cancer Patients with Local and Advanced Bone Metastates

Yazarlar: Hülya AKSOY

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2001 Vol.31 Issue 1, pp.65-68

Belge Tipi: Makale

Yayın Tarihi: 12/2000

Belge Dili: Türkçe

Document ID (Org No.): 2000757434

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Prostate cancer

Deoxypyridinoline

Bone markers

Sayı

Yazarlar:

Hülya AKSOY

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2001 Vol.31 Issue 1, pp.65-68

Belge Tipi:

Makale

Yayın Tarihi:

12/2000

Belge Dili:

Türkçe

Document ID (Org No.):

2000757434

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144