Graves’ disease and thyroiditis can be differentiated using only free thyroid hormone levels

Hilmi Erdem SÜMBÜL; Fettah ACIBUCU

doi:https://doi.org/10.18621/eurj.499174

Makale detayları

Graves’ disease and thyroiditis can be differentiated using only free thyroid hormone levels

Yazarlar:

Hilmi Erdem SÜMBÜL | Fettah ACIBUCU

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Hastalıklar

Dergi:

The European Research Journal 2020 Vol.6 Issue 4, pp.314-318

Belge Tipi:

Makale

Yayın Tarihi:

7/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000662274

Sıklık:

İki Aylık

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.499174

Özet:

 


Objectives: As the treatment approaches of Graves’ disease and thyroiditis are different, differential diagnosis is important. In this study, we analyzed whether it is possible to perform a differential diagnosis for these two conditions by checking the increase ratio of free thyroid hormones.

Methods: In total 156 patients were taken into this study of which 29 were thyroiditis (17 had subacute thyroiditis, 6 had post-partum and 6 had silent thyroiditis) and 127 were Graves patients. The age, free T3 (FT3), free T4 (FT4), thyroid stimulating hormone (TSH) levels, FT3 index (FT3/FT3 upper limit of normal (ULN)), FT4 index (FT4/FT4 ULN) and free thyroid hormone index (FTHI) (FT3 index/FT4 index) of all patients were determined.

Results: A significant difference was found between the mean TSH, FT3 and FT3 index between Graves’ disease and thyroiditis (p = 0.036, p = 0.001 and  p =0.001, respectively). When the groups were compared in terms of FTHI, the difference was found statistically significant (p = 0.001). FTHI was above 1 in all patients with Graves’ disease whereas it was found below 1 in all patients with thyroiditis. There were no statistically significant difference between the Graves’ disease and the thyroiditis in terms of age, FT4 and FT4 index (p = 0.748, p = 0.389 and p = 0.392, respectively).

Conclusion: Based on these results, considering the increases in free thyroid hormone values we can say that it is possible to perform a differential diagnosis of Graves’ disease and thyroiditis, and that this may be used as a practical method to differentiate these two conditions. 


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Makale detayları

Graves’ disease and thyroiditis can be differentiated using only free thyroid hormone levels

Yazarlar: Hilmi Erdem SÜMBÜL | Fettah ACIBUCU

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Hastalıklar

Dergi: The European Research Journal 2020 Vol.6 Issue 4, pp.314-318

Belge Tipi: Makale

Yayın Tarihi: 7/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000662274

Sıklık: İki Aylık

eISSN: 2149-3189

DOI: https://doi.org/10.18621/eurj.499174

Sayı

Yazarlar:

Hilmi Erdem SÜMBÜL | Fettah ACIBUCU

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Hastalıklar

Dergi:

The European Research Journal 2020 Vol.6 Issue 4, pp.314-318

Belge Tipi:

Makale

Yayın Tarihi:

7/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000662274

Sıklık:

İki Aylık

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.499174