Frequency, Microbiological and Clinical Analysis of Peritonitis Episodes in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis: A Five-Year Retrospective Single-Center Experience

İdris Oruç; Hıdır Sarı; Hasan İnce; Eren Eynel

Makale detayları

Frequency, Microbiological and Clinical Analysis of Peritonitis Episodes in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis: A Five-Year Retrospective Single-Center Experience

Yazarlar:

İdris Oruç | Hıdır Sarı | Hasan İnce | Eren Eynel

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Dicle Tıp Dergisi Vol.52 Issue 3, pp.407-414

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001358309

pISSN:

1300-2945

Anahtar kelimeler:

Özet:

 Objective: This study aimed to assess the frequency, microbiological profile, and clinical outcomes of peritonitis in patients receiving Continuous Ambulatory Peritoneal Dialysis CAPD. Methods: This retrospective, cross-sectional study included 52 adult PD patients followed at a tertiary hospital between January 2020 and December 2024. The diagnosis of peritonitis was based on cloudy dialysate, abdominal pain, fever, a dialysate leukocyte count 100 cellsmm³, and a polymorphonuclear cell ratio 50. Microbiological culture results, laboratory findings, and clinical outcomes were analyzed. Results: Among the 52 CAPD patients included in the study, the mean age was 39.96  17.91 years, with an equal gender distribution of 50 female and 50 male. The peritonitis rate was 34.6 n18, with 12 patients experiencing their first episode. All peritonitis cases were bacterial in origin, with two cases showing concomitant fungal coinfection. Microbiological cultures were positive in three patients, revealing Staphylococcus hemolyticus, coagulase-negative Staphylococcus, and Pseudomonas aeruginosa. The mean duration of peritoneal dialysis was 42.85  25.97 months. Residual urine output was preserved in 65.4 n34 of patients. Diabetes mellitus was the most common cause of chronic kidney disease 38.5, followed by hypertension 23.1. Patients with peritonitis exhibited lower mean serum albumin 2.99  0.90 gL and hemoglobin levels 9.75  2.00 gdL, while inflammatory markers procalcitonin 2.21  3.41 μgL and ferritin 490.61  473.26 μgL were elevated. The overall mortality rate was low at 3.8 n2, and 96.2 of patients n50 were discharged. Conclusion: Peritonitis occurred in 34.6 of patients undergoing Continuous Ambulatory Peritoneal Dialysis CAPD, predominantly of bacterial origin. Patients with peritonitis exhibited decreased serum albumin and hemoglobin levels, while inflammatory markers such as procalcitonin and ferritin were elevated. Although mortality was low, systemic effects related to infection were observed. These findings emphasize the importance of early diagnosis and infection control in CAPD patients.

 Objective: This study aimed to assess the frequency, microbiological profile, and clinical outcomes of peritonitis in patients receiving Continuous Ambulatory Peritoneal Dialysis CAPD. Methods: This retrospective, cross-sectional study included 52 adult PD patients followed at a tertiary hospital between January 2020 and December 2024. The diagnosis of peritonitis was based on cloudy dialysate, abdominal pain, fever, a dialysate leukocyte count 100 cellsmm³, and a polymorphonuclear cell ratio 50. Microbiological culture results, laboratory findings, and clinical outcomes were analyzed. Results: Among the 52 CAPD patients included in the study, the mean age was 39.96  17.91 years, with an equal gender distribution of 50 female and 50 male. The peritonitis rate was 34.6 n18, with 12 patients experiencing their first episode. All peritonitis cases were bacterial in origin, with two cases showing concomitant fungal coinfection. Microbiological cultures were positive in three patients, revealing Staphylococcus hemolyticus, coagulase-negative Staphylococcus, and Pseudomonas aeruginosa. The mean duration of peritoneal dialysis was 42.85  25.97 months. Residual urine output was preserved in 65.4 n34 of patients. Diabetes mellitus was the most common cause of chronic kidney disease 38.5, followed by hypertension 23.1. Patients with peritonitis exhibited lower mean serum albumin 2.99  0.90 gL and hemoglobin levels 9.75  2.00 gdL, while inflammatory markers procalcitonin 2.21  3.41 μgL and ferritin 490.61  473.26 μgL were elevated. The overall mortality rate was low at 3.8 n2, and 96.2 of patients n50 were discharged. Conclusion: Peritonitis occurred in 34.6 of patients undergoing Continuous Ambulatory Peritoneal Dialysis CAPD, predominantly of bacterial origin. Patients with peritonitis exhibited decreased serum albumin and hemoglobin levels, while inflammatory markers such as procalcitonin and ferritin were elevated. Although mortality was low, systemic effects related to infection were observed. These findings emphasize the importance of early diagnosis and infection control in CAPD patients.

 Objective: This study aimed to assess the frequency, microbiological profile, and clinical outcomes of peritonitis in patients receiving Continuous Ambulatory Peritoneal Dialysis CAPD. Methods: This retrospective, cross-sectional study included 52 adult PD patients followed at a tertiary hospital between January 2020 and December 2024. The diagnosis of peritonitis was based on cloudy dialysate, abdominal pain, fever, a dialysate leukocyte count 100 cellsmm³, and a polymorphonuclear cell ratio 50. Microbiological culture results, laboratory findings, and clinical outcomes were analyzed. Results: Among the 52 CAPD patients included in the study, the mean age was 39.96  17.91 years, with an equal gender distribution of 50 female and 50 male. The peritonitis rate was 34.6 n18, with 12 patients experiencing their first episode. All peritonitis cases were bacterial in origin, with two cases showing concomitant fungal coinfection. Microbiological cultures were positive in three patients, revealing Staphylococcus hemolyticus, coagulase-negative Staphylococcus, and Pseudomonas aeruginosa. The mean duration of peritoneal dialysis was 42.85  25.97 months. Residual urine output was preserved in 65.4 n34 of patients. Diabetes mellitus was the most common cause of chronic kidney disease 38.5, followed by hypertension 23.1. Patients with peritonitis exhibited lower mean serum albumin 2.99  0.90 gL and hemoglobin levels 9.75  2.00 gdL, while inflammatory markers procalcitonin 2.21  3.41 μgL and ferritin 490.61  473.26 μgL were elevated. The overall mortality rate was low at 3.8 n2, and 96.2 of patients n50 were discharged. Conclusion: Peritonitis occurred in 34.6 of patients undergoing Continuous Ambulatory Peritoneal Dialysis CAPD, predominantly of bacterial origin. Patients with peritonitis exhibited decreased serum albumin and hemoglobin levels, while inflammatory markers such as procalcitonin and ferritin were elevated. Although mortality was low, systemic effects related to infection were observed. These findings emphasize the importance of early diagnosis and infection control in CAPD patients.

 Öz Giriş: Peritonit, periton diyalizinin PD önemli bir komplikasyonu olup hastaneye yatış, tedavi maliyetlerinde artış ve uzun dönemde periton membran hasarına yol açabilmektedir. Bu çalışmada, Sürekli Ayaktan Periton Diyalizi SAPD uygulanan hastalarda peritonit sıklığı ve klinik sonuçlarının değerlendirilmesi amaçlanmıştır. Yöntemler: Bu retrospektif, kesitsel çalışmaya Ocak 2020-Aralık 2024 tarihleri arasında üçüncü basamak bir hastanede takip edilen 52 erişkin PD hastası 50 kadın, ortalama yaş 39,96  17,91 yıl dahil edildi. Peritonit tanısı bulanık diyalizat, karın ağrısı, ateş ve diyalizat sıvısında lökosit sayısının 100 hücremm³ ve polimorfonükleer hücre oranının 50 olması kriterlerine dayandırıldı. Mikrobiyolojik kültür sonuçları, laboratuvar bulguları ve klinik sonuçlar incelendi. Bulgular: Çalışmaya dahil edilen 52 CAPD hastasının yaş ortalaması 39,96  17,91 yıl olup, cinsiyet dağılımı 50 kadın ve 50 erkek olarak eşit dağıldı. Peritonit oranı 34,6 n18 olarak belirlendi ve 12 hasta ilk peritonit atağını yaşadı. Tüm peritonit vakaları bakteriyel kökenli olup, iki hastada eşlik eden mantar enfeksiyonu görüldü. Mikrobiyolojik kültürlerde üç hastada pozitif sonuç elde edildi; bu mikroorganizmalar Staphylococcus hemolyticus, koagülaz negatif Staphylococcus ve Pseudomonas aeruginosa idi. Ortalama periton diyaliz süresi 42,85  25,97 ay olarak bulundu. Hastaların 65,4ünde n34 rezidüel idrar çıkışı mevcuttu. Kronik böbrek hastalığının en sık nedeni diyabet 38,5, bunu hipertansiyon 23,1 takip etti. Peritonitli hastalarda serum albümin 2,99  0,90 gL ve hemoglobin 9,75  2,00 gdL düzeyleri düşüktü; inflamatuar belirteçler prokalsitonin 2,21  3,41 μgL ve ferritin 490,61  473,26 μgL ise yükselmişti. Genel mortalite oranı 3,8 n2 düşük bulundu ve hastaların 96,2si n50 taburcu edildi. Sonuç: Sürekli Ayaktan Periton Diyalizi SAPD uygulanan hastaların 34,6sında peritonit görülmüş olup, vakaların çoğu bakteriyel kökenlidir. Peritonitli hastalarda serum albümin ve hemoglobin seviyeleri azalmış, prokalsitonin ve ferritin gibi inflamatuar belirteçler yükselmiştir. Mortalite düşük olmakla birlikte, enfeksiyona bağlı sistemik etkiler gözlenmiştir. Bu bulgular, SAPD hastalarında peritonitin erken tanısı ve enfeksiyon kontrolünün önemini vurgulamaktadır.

Makale detayları

Frequency, Microbiological and Clinical Analysis of Peritonitis Episodes in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis: A Five-Year Retrospective Single-Center Experience

Yazarlar:

İdris Oruç | Hıdır Sarı | Hasan İnce | Eren Eynel

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Dicle Tıp Dergisi Vol.52 Issue 3, pp.407-414

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001358309

pISSN:

1300-2945

Peritoneal dialysis

peritonitis

CAPD

infection

clinical outcomesPeriton diyalizi

peritonit

SAPD

enfeksiyon

klinik sonuçlar.

Sayı

Makale detayları

Yazarlar: İdris Oruç | Hıdır Sarı | Hasan İnce | Eren Eynel

Yayıncı: Dicle University

Ana Başlıklar: Sağlık Kurumları Yönetimi | Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi: Dicle Tıp Dergisi Vol.52 Issue 3, pp.407-414

Belge Tipi: Makale

Yayın Tarihi: 9/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001358309

pISSN: 1300-2945

Sayı

Yazarlar:

İdris Oruç | Hıdır Sarı | Hasan İnce | Eren Eynel

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Dicle Tıp Dergisi Vol.52 Issue 3, pp.407-414

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001358309

pISSN:

1300-2945