Inflammatory indices as an indicator of acute pancreatitis severity

Muhammed Fuad Uslu; Esra Timurkaan; Mustafa Timurkaan; Mustafa Yılmaz

Makale detayları

Inflammatory indices as an indicator of acute pancreatitis severity

Yazarlar:

Muhammed Fuad Uslu | Esra Timurkaan | Mustafa Timurkaan | Mustafa Yılmaz

Yayıncı:

Hatay Mustafa Kemal University

Ana Başlıklar:

Internal Diseases

Dergi:

Interdisciplinary Medical Journal Vol.16 Issue 54, pp.38-44

Belge Tipi:

Makale

Yayın Tarihi:

12/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344354

pISSN:

2980-1915

Anahtar kelimeler:

Özet:

 Objective: The present study aimed to compare C-reactive protein CRP, neutrophillymphocyte ratio NLR, neutrophilalbumin ratio NAR, plateletleukocyte ratio PLR, systemic immune inflammation SII, systemic inflammation response index SIRI and Ranson criteria associated with inflammation in acute pancreatitis AP. Thus, the study aimed to analyze the significance ranking of these parameters in terms of disease severity. Method: The present retrospective study was conducted after the ethics committee approval was obtained. The study included 221 AP patients visited hospital between 01.01.2018 and 31.12.2023. The patients were categorized into two groups based on Ranson criteria: Group 1 Ranson2, n147 and Group 2 Ranson3, n74. Basic participant demographics, laboratory reports, CRP, NLR, NAR, PLR, SII, SIRI and hospitalization periods were recorded in a data form, and the findings were analyzed. Results: There was no difference between the groups based on gender p0.094. The Group 2 patients were older p0.001 than the ones in Group 1. Furthermore, CRP p0.001, NLR p0.001, NAR p0.001, PLR p0.001, SII p0.001 and SIRI p0.001 were higher in Group 2 patients when compared to Group 1. Also, the hospitalization period was significantly longer in Group 2 p0.001 compared to Group 1. Conclusion: In the study, it was determined that the CRP, NAR, PLR, NLR, SII and SIRI findings were significantly higher in AP patients with a Ranson criteria  3, and a positive correlation was found between Ranson criteria and inflammatory parameters.

 Objective: The present study aimed to compare C-reactive protein CRP, neutrophillymphocyte ratio NLR, neutrophilalbumin ratio NAR, plateletleukocyte ratio PLR, systemic immune inflammation SII, systemic inflammation response index SIRI and Ranson criteria associated with inflammation in acute pancreatitis AP. Thus, the study aimed to analyze the significance ranking of these parameters in terms of disease severity. Method: The present retrospective study was conducted after the ethics committee approval was obtained. The study included 221 AP patients visited hospital between 01.01.2018 and 31.12.2023. The patients were categorized into two groups based on Ranson criteria: Group 1 Ranson2, n147 and Group 2 Ranson3, n74. Basic participant demographics, laboratory reports, CRP, NLR, NAR, PLR, SII, SIRI and hospitalization periods were recorded in a data form, and the findings were analyzed. Results: There was no difference between the groups based on gender p0.094. The Group 2 patients were older p0.001 than the ones in Group 1. Furthermore, CRP p0.001, NLR p0.001, NAR p0.001, PLR p0.001, SII p0.001 and SIRI p0.001 were higher in Group 2 patients when compared to Group 1. Also, the hospitalization period was significantly longer in Group 2 p0.001 compared to Group 1. Conclusion: In the study, it was determined that the CRP, NAR, PLR, NLR, SII and SIRI findings were significantly higher in AP patients with a Ranson criteria  3, and a positive correlation was found between Ranson criteria and inflammatory parameters.

 Objective: The present study aimed to compare C-reactive protein CRP, neutrophillymphocyte ratio NLR, neutrophilalbumin ratio NAR, plateletleukocyte ratio PLR, systemic immune inflammation SII, systemic inflammation response index SIRI and Ranson criteria associated with inflammation in acute pancreatitis AP. Thus, the study aimed to analyze the significance ranking of these parameters in terms of disease severity. Method: The present retrospective study was conducted after the ethics committee approval was obtained. The study included 221 AP patients visited hospital between 01.01.2018 and 31.12.2023. The patients were categorized into two groups based on Ranson criteria: Group 1 Ranson2, n147 and Group 2 Ranson3, n74. Basic participant demographics, laboratory reports, CRP, NLR, NAR, PLR, SII, SIRI and hospitalization periods were recorded in a data form, and the findings were analyzed. Results: There was no difference between the groups based on gender p0.094. The Group 2 patients were older p0.001 than the ones in Group 1. Furthermore, CRP p0.001, NLR p0.001, NAR p0.001, PLR p0.001, SII p0.001 and SIRI p0.001 were higher in Group 2 patients when compared to Group 1. Also, the hospitalization period was significantly longer in Group 2 p0.001 compared to Group 1. Conclusion: In the study, it was determined that the CRP, NAR, PLR, NLR, SII and SIRI findings were significantly higher in AP patients with a Ranson criteria  3, and a positive correlation was found between Ranson criteria and inflammatory parameters.

 Objective: The present study aimed to compare C-reactive protein CRP, neutrophillymphocyte ratio NLR, neutrophilalbumin ratio NAR, plateletleukocyte ratio PLR, systemic immune inflammation SII, systemic inflammation response index SIRI and Ranson criteria associated with inflammation in acute pancreatitis AP. Thus, the study aimed to analyze the significance ranking of these parameters in terms of disease severity. Method: The present retrospective study was conducted after the ethics committee approval was obtained. The study included 221 AP patients visited hospital between 01.01.2018 and 31.12.2023. The patients were categorized into two groups based on Ranson criteria: Group 1 Ranson2, n147 and Group 2 Ranson3, n74. Basic participant demographics, laboratory reports, CRP, NLR, NAR, PLR, SII, SIRI and hospitalization periods were recorded in a data form, and the findings were analyzed. Results: There was no difference between the groups based on gender p0.094. The Group 2 patients were older p0.001 than the ones in Group 1. Furthermore, CRP p0.001, NLR p0.001, NAR p0.001, PLR p0.001, SII p0.001 and SIRI p0.001 were higher in Group 2 patients when compared to Group 1. Also, the hospitalization period was significantly longer in Group 2 p0.001 compared to Group 1. Conclusion: In the study, it was determined that the CRP, NAR, PLR, NLR, SII and SIRI findings were significantly higher in AP patients with a Ranson criteria  3, and a positive correlation was found between Ranson criteria and inflammatory parameters.

Makale detayları

Inflammatory indices as an indicator of acute pancreatitis severity

Yazarlar:

Muhammed Fuad Uslu | Esra Timurkaan | Mustafa Timurkaan | Mustafa Yılmaz

Yayıncı:

Hatay Mustafa Kemal University

Ana Başlıklar:

Internal Diseases

Dergi:

Interdisciplinary Medical Journal Vol.16 Issue 54, pp.38-44

Belge Tipi:

Makale

Yayın Tarihi:

12/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344354

pISSN:

2980-1915

Acute pancreatitis

Systemic Immune Inflammation and Systemic Inflammation Response Index

Neutrophil / Lymphocyte Ratio

Neutrophil / Albumin Ratio

Platelet to Leukocyte Ratio.

Sayı

Makale detayları

Inflammatory indices as an indicator of acute pancreatitis severity

Yazarlar: Muhammed Fuad Uslu | Esra Timurkaan | Mustafa Timurkaan | Mustafa Yılmaz

Yayıncı: Hatay Mustafa Kemal University

Ana Başlıklar: Internal Diseases

Dergi: Interdisciplinary Medical Journal Vol.16 Issue 54, pp.38-44

Belge Tipi: Makale

Yayın Tarihi: 12/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001344354

pISSN: 2980-1915

Acute pancreatitis

Systemic Immune Inflammation and Systemic Inflammation Response Index

Neutrophil / Lymphocyte Ratio

Neutrophil / Albumin Ratio

Platelet to Leukocyte Ratio.

Sayı

Yazarlar:

Muhammed Fuad Uslu | Esra Timurkaan | Mustafa Timurkaan | Mustafa Yılmaz

Yayıncı:

Hatay Mustafa Kemal University

Ana Başlıklar:

Internal Diseases

Dergi:

Interdisciplinary Medical Journal Vol.16 Issue 54, pp.38-44

Belge Tipi:

Makale

Yayın Tarihi:

12/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344354

pISSN:

2980-1915