Does High Blood Pressure Have an Effect on Intervertebral Fibrocartilage Histology?

Erhan Şahin; Damla Gül Fındık; Özlem Türelik

Makale detayları

Does High Blood Pressure Have an Effect on Intervertebral Fibrocartilage Histology?

Yazarlar:

Erhan Şahin | Damla Gül Fındık | Özlem Türelik

Yayıncı:

Bingol University

Ana Başlıklar:

Hücre Metabolizması | Yapısal Biyoloji

Dergi:

Türk Doğa ve Fen Dergisi Vol.14 Issue 1, pp.192-196

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344029

pISSN:

2149-6366

Anahtar kelimeler:

Özet:

 Since the cartilage tissue is fed by the vessels in the surrounding connective tissue, it is a very difficult tissue to repair. Therefore, cardiovascular diseases primarily affect the cartilage tissue. In this study, the possible effects of high blood pressure on discus intervertebralis were examined histopathologically and histomorphometrically. Discus intervertebralis of 13 normotensive and 13 hypertensive patients were compared histopathologically and histomorphometrically. Demographic information of the patients was obtained from the patient registration system of the hospital. Hematoxylin-eosin-stained slices were used for histopathological evaluation. In histological sections, chondrocytes and lacunae diameters were measured at 400x magnification in 10 different areas with a computer morphometric measurement program. Discus intervertebralis of normotensive and hypertensive patients did not differ in terms of chondrocyte count and lacunae diameter. The mean age of hypertensive patients 61.6913.55 was higher than the mean age of normotensive patients 428.84 p0.05. The gender ratio of the groups did not show a statistical difference p0.05. In this study, it was shown that the discus intervertebralis of normotensive and hypertensive patients who underwent lumbar discectomy were not different in terms of histopathologically and histomorphometrically in terms of chondrocyte number and lacuna diameter.

 Since the cartilage tissue is fed by the vessels in the surrounding connective tissue, it is a very difficult tissue to repair. Therefore, cardiovascular diseases primarily affect the cartilage tissue. In this study, the possible effects of high blood pressure on discus intervertebralis were examined histopathologically and histomorphometrically. Discus intervertebralis of 13 normotensive and 13 hypertensive patients were compared histopathologically and histomorphometrically. Demographic information of the patients was obtained from the patient registration system of the hospital. Hematoxylin-eosin-stained slices were used for histopathological evaluation. In histological sections, chondrocytes and lacunae diameters were measured at 400x magnification in 10 different areas with a computer morphometric measurement program. Discus intervertebralis of normotensive and hypertensive patients did not differ in terms of chondrocyte count and lacunae diameter. The mean age of hypertensive patients 61.6913.55 was higher than the mean age of normotensive patients 428.84 p0.05. The gender ratio of the groups did not show a statistical difference p0.05. In this study, it was shown that the discus intervertebralis of normotensive and hypertensive patients who underwent lumbar discectomy were not different in terms of histopathologically and histomorphometrically in terms of chondrocyte number and lacuna diameter.

 Since the cartilage tissue is fed by the vessels in the surrounding connective tissue, it is a very difficult tissue to repair. Therefore, cardiovascular diseases primarily affect the cartilage tissue. In this study, the possible effects of high blood pressure on discus intervertebralis were examined histopathologically and histomorphometrically. Discus intervertebralis of 13 normotensive and 13 hypertensive patients were compared histopathologically and histomorphometrically. Demographic information of the patients was obtained from the patient registration system of the hospital. Hematoxylin-eosin-stained slices were used for histopathological evaluation. In histological sections, chondrocytes and lacunae diameters were measured at 400x magnification in 10 different areas with a computer morphometric measurement program. Discus intervertebralis of normotensive and hypertensive patients did not differ in terms of chondrocyte count and lacunae diameter. The mean age of hypertensive patients 61.6913.55 was higher than the mean age of normotensive patients 428.84 p0.05. The gender ratio of the groups did not show a statistical difference p0.05. In this study, it was shown that the discus intervertebralis of normotensive and hypertensive patients who underwent lumbar discectomy were not different in terms of histopathologically and histomorphometrically in terms of chondrocyte number and lacuna diameter.

 Kıkırdak doku, çevresindeki bağ dokusunda bulunan damarlarla beslendiğinden onarımı çok zor bir dokudur. Bu nedenle kardiyovasküler hastalıklar öncelikle kıkırdak dokusunu etkiler. Bu çalışmada, yüksek tansiyonun discus intervertebralis üzerindeki olası etkileri histopatolojik ve histomorfometrik olarak incelenmiştir. 13 normotansif ve 13 hipertansif hastanın discus intervertebralisi histopatolojik ve histomorfometrik olarak karşılaştırılmıştır. Hastaların demografik bilgileri hastanenin hasta kayıt sisteminden elde edilmiştir. Histopatolojik değerlendirme için hematoksilen-eozin boyalı kesitler kullanılmıştır. Histolojik kesitlerde, kondrosit ve lakün çapları, morfometrik ölçüm programı ile 10 farklı alanda 400x büyütmede ölçülmüştür. Normotansif ve hipertansif hastaların discus intervertebralisi kondrosit sayısı ve lakün çapı açısından farklılık göstermemiştir. Hipertansif hastaların yaş ortalaması 61.6913.55, normotansif hastaların yaş ortalamasından 428.84 yüksekti p0.05. Grupların cinsiyet oranı istatistiksel olarak fark göstermedi p0.05. Bu çalışmada lomber disektomi uygulanan normotansif ve hipertansif hastaların discus intervertebralisinin histopatolojik ve histomorfometri kondrosit sayısı ve lakuna çapı açısından açıdan farklı olmadığı gösterildi.

Makale detayları

Does High Blood Pressure Have an Effect on Intervertebral Fibrocartilage Histology?

Yazarlar:

Erhan Şahin | Damla Gül Fındık | Özlem Türelik

Yayıncı:

Bingol University

Ana Başlıklar:

Hücre Metabolizması | Yapısal Biyoloji

Dergi:

Türk Doğa ve Fen Dergisi Vol.14 Issue 1, pp.192-196

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344029

pISSN:

2149-6366

Fibrocartilage

intervertebral disc

High Blood Pressure

Histopathology

HistomorphometryFibröz kıkırdak

omurlar arası disk

Yüksek Tansiyon

Histopatoloji

Histomorfometri.

Sayı

Makale detayları

Yazarlar: Erhan Şahin | Damla Gül Fındık | Özlem Türelik

Yayıncı: Bingol University

Ana Başlıklar: Hücre Metabolizması | Yapısal Biyoloji

Dergi: Türk Doğa ve Fen Dergisi Vol.14 Issue 1, pp.192-196

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001344029

pISSN: 2149-6366

Sayı

Yazarlar:

Erhan Şahin | Damla Gül Fındık | Özlem Türelik

Yayıncı:

Bingol University

Ana Başlıklar:

Hücre Metabolizması | Yapısal Biyoloji

Dergi:

Türk Doğa ve Fen Dergisi Vol.14 Issue 1, pp.192-196

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001344029

pISSN:

2149-6366