In The Presence of Risk Factors High Rate of Incidental Multifocal Microcarcinoma Detection in Solitary Thyroid Nodule and Multinodular Goitre Justifies Total Thyroidectomy

Nevin Sakoğlu

Makale detayları

In The Presence of Risk Factors High Rate of Incidental Multifocal Microcarcinoma Detection in Solitary Thyroid Nodule and Multinodular Goitre Justifies Total Thyroidectomy

Yazarlar:

Nevin Sakoğlu

Yayıncı:

Dicle University

Ana Başlıklar:

Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 4, pp.510-521

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001334152

pISSN:

1300-2945

Anahtar kelimeler:

Özet:

 Aim: Thyroid nodules are commonly encountered with increasing age. Majority of them are benign. In the present study, our goal was to identify both the false negative rate FNR of preoperative cytology, radiology results, risk factors for malignancy, and the prevalence of thyroid carcinoma in cases to whom operation performed for solitary thyroid nodule STN with multinodular goitre MNG and the final histopathological report. Methods: A retrospective study among 141 patients who were operated for suspicion of thyroid cancer between 2019-2022. 118 were women 83.6 and 23 were men 16.3. The mean age was 50.223.1. Demographic characteristics and factors predicting malignancy were questioned for all patients preoperatively. Preoperative ultrasonography US, fine needle aspiration cytology FNAc results and postoperative histopathology data were collected. Ultrasound features ACR-TIRADS, FNAc results, histopathology records, risk factors and malignancy rates was registered. Statistical analysis was done with Fishers precision and Mann-Whitney U tests. Results: 141 patients underwent total thyroidectomy for STN n28, 19.8 and MNG n113, 80.1. The correlation of FNAc with final histopathology revealed that FNR in MNG was more often than that of STN 33.3 vs 66.6, p0.001. Malignancy was detected in 43 of 141 patients with total thyroidectomy due to STN and MNG 30.4.Family history and previous radiotherapy were risk factors in patients with STN 25. The histopathology results of 129 patients were compatible with ACR-TIRADS in ultrasound 91.4. Conclusion: Although multinodular goiter MNG is generally believed to have a lower risk of malignancy compared to solitary thyroid nodules STN, the prevalence of malignancy is significantly higher in STN and MNG. Optimal patient management depends on a good interaction between radiologist, pathologist and surgeon to decrease false negative and false positive cases.

 Aim: Thyroid nodules are commonly encountered with increasing age. Majority of them are benign. In the present study, our goal was to identify both the false negative rate FNR of preoperative cytology, radiology results, risk factors for malignancy, and the prevalence of thyroid carcinoma in cases to whom operation performed for solitary thyroid nodule STN with multinodular goitre MNG and the final histopathological report. Methods: A retrospective study among 141 patients who were operated for suspicion of thyroid cancer between 2019-2022. 118 were women 83.6 and 23 were men 16.3. The mean age was 50.223.1. Demographic characteristics and factors predicting malignancy were questioned for all patients preoperatively. Preoperative ultrasonography US, fine needle aspiration cytology FNAc results and postoperative histopathology data were collected. Ultrasound features ACR-TIRADS, FNAc results, histopathology records, risk factors and malignancy rates was registered. Statistical analysis was done with Fishers precision and Mann-Whitney U tests. Results: 141 patients underwent total thyroidectomy for STN n28, 19.8 and MNG n113, 80.1. The correlation of FNAc with final histopathology revealed that FNR in MNG was more often than that of STN 33.3 vs 66.6, p0.001. Malignancy was detected in 43 of 141 patients with total thyroidectomy due to STN and MNG 30.4.Family history and previous radiotherapy were risk factors in patients with STN 25. The histopathology results of 129 patients were compatible with ACR-TIRADS in ultrasound 91.4. Conclusion: Although multinodular goiter MNG is generally believed to have a lower risk of malignancy compared to solitary thyroid nodules STN, the prevalence of malignancy is significantly higher in STN and MNG. Optimal patient management depends on a good interaction between radiologist, pathologist and surgeon to decrease false negative and false positive cases.

 Aim: Thyroid nodules are commonly encountered with increasing age. Majority of them are benign. In the present study, our goal was to identify both the false negative rate FNR of preoperative cytology, radiology results, risk factors for malignancy, and the prevalence of thyroid carcinoma in cases to whom operation performed for solitary thyroid nodule STN with multinodular goitre MNG and the final histopathological report. Methods: A retrospective study among 141 patients who were operated for suspicion of thyroid cancer between 2019-2022. 118 were women 83.6 and 23 were men 16.3. The mean age was 50.223.1. Demographic characteristics and factors predicting malignancy were questioned for all patients preoperatively. Preoperative ultrasonography US, fine needle aspiration cytology FNAc results and postoperative histopathology data were collected. Ultrasound features ACR-TIRADS, FNAc results, histopathology records, risk factors and malignancy rates was registered. Statistical analysis was done with Fishers precision and Mann-Whitney U tests. Results: 141 patients underwent total thyroidectomy for STN n28, 19.8 and MNG n113, 80.1. The correlation of FNAc with final histopathology revealed that FNR in MNG was more often than that of STN 33.3 vs 66.6, p0.001. Malignancy was detected in 43 of 141 patients with total thyroidectomy due to STN and MNG 30.4.Family history and previous radiotherapy were risk factors in patients with STN 25. The histopathology results of 129 patients were compatible with ACR-TIRADS in ultrasound 91.4. Conclusion: Although multinodular goiter MNG is generally believed to have a lower risk of malignancy compared to solitary thyroid nodules STN, the prevalence of malignancy is significantly higher in STN and MNG. Optimal patient management depends on a good interaction between radiologist, pathologist and surgeon to decrease false negative and false positive cases.

 Aim: Thyroid nodules are commonly encountered with increasing age. Majority of them are benign. In the present study, our goal was to identify both the false negative rate FNR of preoperative cytology, radiology results, risk factors for malignancy, and the prevalence of thyroid carcinoma in cases to whom operation performed for solitary thyroid nodule STN with multinodular goitre MNG and the final histopathological report. Methods: A retrospective study among 141 patients who were operated for suspicion of thyroid cancer between 2019-2022. 118 were women 83.6 and 23 were men 16.3. The mean age was 50.223.1. Demographic characteristics and factors predicting malignancy were questioned for all patients preoperatively. Preoperative ultrasonography US, fine needle aspiration cytology FNAc results and postoperative histopathology data were collected. Ultrasound features ACR-TIRADS, FNAc results, histopathology records, risk factors and malignancy rates was registered. Statistical analysis was done with Fishers precision and Mann-Whitney U tests. Results: 141 patients underwent total thyroidectomy for STN n28, 19.8 and MNG n113, 80.1. The correlation of FNAc with final histopathology revealed that FNR in MNG was more often than that of STN 33.3 vs 66.6, p0.001. Malignancy was detected in 43 of 141 patients with total thyroidectomy due to STN and MNG 30.4.Family history and previous radiotherapy were risk factors in patients with STN 25. The histopathology results of 129 patients were compatible with ACR-TIRADS in ultrasound 91.4. Conclusion: Although multinodular goiter MNG is generally believed to have a lower risk of malignancy compared to solitary thyroid nodules STN, the prevalence of malignancy is significantly higher in STN and MNG. Optimal patient management depends on a good interaction between radiologist, pathologist and surgeon to decrease false negative and false positive cases.

Makale detayları

In The Presence of Risk Factors High Rate of Incidental Multifocal Microcarcinoma Detection in Solitary Thyroid Nodule and Multinodular Goitre Justifies Total Thyroidectomy

Yazarlar:

Nevin Sakoğlu

Yayıncı:

Dicle University

Ana Başlıklar:

Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 4, pp.510-521

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001334152

pISSN:

1300-2945

Cytology

solitary thyroid nodule

multinodular goitre

malignancy

Sayı

Makale detayları

In The Presence of Risk Factors High Rate of Incidental Multifocal Microcarcinoma Detection in Solitary Thyroid Nodule and Multinodular Goitre Justifies Total Thyroidectomy

Yazarlar: Nevin Sakoğlu

Yayıncı: Dicle University

Ana Başlıklar: Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi: Dicle Tıp Dergisi Vol.51 Issue 4, pp.510-521

Belge Tipi: Makale

Yayın Tarihi: 12/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001334152

pISSN: 1300-2945

Cytology

solitary thyroid nodule

multinodular goitre

malignancy

Sayı

Yazarlar:

Nevin Sakoğlu

Yayıncı:

Dicle University

Ana Başlıklar:

Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 4, pp.510-521

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001334152

pISSN:

1300-2945